The effects of age and gender on the optimal premedication dose of intramuscular midazolam

Anesthesia and Analgesia

Volumn 86, Issue 5, 1998, Pages 1103-1108

  Nishiyama, Tomoki ^a,c   Matsukawa, Takashi ^b   Hanaoka, Kazuo ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF YAMANASHI   (Japan)

^c NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATROPINE; MIDAZOLAM;

ADULT; AGED; AGING; AMNESIA; ANESTHESIA INDUCTION; AREFLEXIA; ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DROWSINESS; DRUG MIXTURE; EYELID REFLEX; FEMALE; GENDER; HUMAN; INTRAMUSCULAR DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MALE; PATIENT MONITORING; PREMEDICATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEDATION; TRANQUILIZING ACTIVITY;

ADULT; AGE FACTORS; AGED; ANTI-ANXIETY AGENTS; BLOOD PRESSURE; FEMALE; HEART RATE; HUMANS; MALE; MIDAZOLAM; MIDDLE AGED; PREANESTHETIC MEDICATION; RESPIRATION; SEX FACTORS;

EID: 0031980664     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-199805000-00038     Document Type: Article

References (17)

1. Fragen RJ, Funk DI, Avram MJ, et al. Midazolam versus hydroxyzine as intramuscular premedicant. Can Anaesth Soc J 1983;30:136-41.
2. Richardson MG, Wu CL, Hussein A. Midazolam premedication increases sedation but does not prolong discharge times after brief outpatient general anesthesia for laparoscopic tubal sterilization. Anesth Analg 1997;85:301-5.
3. Malinovsky JM, Populaire C, Cozien A, et al. Premedication with midazolam in children: effect of intranasal, rectal and oral routes on plasma midazolam concentrations. Anaesthesia 1995; 50:351-4.
4. Lim TW, Thomas E, Choo SM. Premedication with midazolam is more effective by the sublingual than oral route. Can J Anaesth 1997;44:723-6.
5. Raybould D, Bradshaw EG. Premedication for day case surgery: a study of oral midazolam. Anaesthesia 1987;42:591-5.
6. Conner JT, Katz RL, Pagano RR, Graham CW. RO 21-3981 for intravenous surgical premedication and induction of anesthesia. Anesth Analg 1978;57:l-5.
7. Yano T, Haratake Y, Urata K, Morioka T. Sedative and respiratory effects of intramuscular midazolam as a premedicant: Influence of gender. J Anesth 1994;8:383-6.
8. Nishiyama T, Nagase M, Tamai H, et al. Optimal administration time of intramuscular midazolam premedication. J Anesth 1995; 9:11-4.
9. Shafer A, White PF, Urquhart ML, Doze VA. Outpatient premedication: use of midazolam and opioid analgesics. Anesthesiology 1989;71:495-501.
10. Holazo AA, Winkler MG, Patel IH. Effects of age, gender and oral contraceptives on intramuscular midazolam pharmacokinetics. J Clin Pharmacol 1988;28:1040-5.
11. Reinhart K, Dallinger-Stiller G, Dennhardt R, et al. Comparison of midazolam, diazepam and placebo i.m. as premedication for regional anaesthesia: a randomized double-blind study. Br J Anaesth 1985;7:294-9.
12. Tabuchi Y. The effect of age and gender on the effect of midazolam as intramuscular premedicant. Jpn J Anesthesiol 1992/41: 938-44.
13. Greenblatt D], Abernethy DR, Locniskar A, et al. Effect of age, gender, and obesity on midazolam kinetics. Anesthesiology 1984;61:27-35.
14. Bell GD, Spickett GP, Reeve PA, et al. Intravenous midazolam for upper gastrointestinal endoscopy: a study of 800 consecutive cases relating dose to age and sex of patient. Br J Clin Pharmacol 1987;23:241-3.
15. Wong HY, Fragen RJ, Dünn K. Dose-finding study of intramuscular midazolam preanesthetic medication in the elderly. Anesthesiology 1991;74:675-9.
16. Smith MT, Heazlewood V, Eadie MJ, et al. Pharmacokinetics of midazolam in the aged. Eur J Clin Pharmacol 19S4;26:381-8.
17. Jacobs JR, Reves JG, Marty J, et al. Aging increases pharmacodynamic sensitivity to the hypnotic effects of midazolam. Anesth Analg 1995;80:143-8.