CD3-CD4-CD8-CD56-CD19-CD14- cells and CD3+CD8 dull-positive cells produce IL-4 in AIDS patients

British Journal of Haematology

Volumn 101, Issue 1, 1998, Pages 74-77

  Honda, Junichi ^a   Okubo, Yasemitsu ^a   Tanaka, Ken ^a   Kusaba, Mikako ^a   Kumagai, Mutsuko ^a   Saruwatari, Naoko ^a   Oizumi, Kotaro ^a  

^a KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

CD4; HIV; IL 4; Th1; Th2

Indexed keywords

CD14 ANTIGEN; CD19 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD56 ANTIGEN; CD8 ANTIGEN; INTERLEUKIN 4;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; ANTIGEN EXPRESSION; ARTICLE; CASE REPORT; CELL DIFFERENTIATION; CELL FUNCTION; FLOW CYTOMETRY; HELPER CELL; HUMAN; HUMORAL IMMUNITY; IMMUNOGLOBULIN PRODUCTION; MALE; MONONUCLEAR CELL; PRIORITY JOURNAL; TECHNIQUE;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ADULT; ANTIGENS, CD; ANTIGENS, CD14; ANTIGENS, CD19; ANTIGENS, CD3; ANTIGENS, CD4; ANTIGENS, CD56; ANTIGENS, CD8; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOGLOBULIN G; INTERLEUKIN-4; MALE; MIDDLE AGED; PHENOTYPE; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 0031979010     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1998.00647.x     Document Type: Article

References (12)

1. Cheever, A.W., Williams, M.E., Wynn, T.A., Finkelmann, E.D., Seder, R.A., Cox, T.M., Hieny, S., Casper, P. & Sher, A, (1994) Anti-IL-4 treatment of Schistosoma mansoni-infected mice inhibits development of T cells and non-B, non-T cells expressing Th2 cytokines while decreasing egg-induced hepatic fibrosis. Journal of Immunology, 153, 753-759.
2. Cherwinski, H.M., Schumacher, J.H., Brown, K.D. & Monsmann, T.R. (1987) Two types of muse helper T cell clone, III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies, Journal of Experimental Medicine, 166, 1229-1244.
3. Chu, C.C., Max, E.E. & Paul, W.E. (1993) DNA rearrangement can account for in vitro switching to IgG1. Journal of Experimental Medicine, 178, 1381-1390.
4. Del Prete, G.F., De Carli, M., Ricci, M. & Romagnani, S. (1991) Helper activity for immunoglobulin synthesis of T helper type 1 (Th1) and Th2 human T cell clone: the help of Th1 clones is limited by their cylolytic capacity, Journal of Experimental Medicine, 174, 809-813.
5. Fauci, A.S. (1993) Multifactorial nature of human immunodeficiency virus disease: implications for therapy, Science, 262, 1011-1018.
6. Kuwano, K., Arai, S., Munakata, T., Tomita, Y., Yoshitake, Y. & Kunagai, K. (1986) Suppressive effect of human natural killer cells on Epstein-Barr virus-induced immunoglobulin synthesis. Journal of lmmunology, 137, 1462-1467.
7. + T cells showing B cell helper function and reduced cytolytic activity in human immunodeficiency virus type 1 infection. Journal of Experimental Medicine, 180, 489-495.
8. Mauri, C., Williams, R.O., Walmsley, M. & Feldmann, M. (1996) Relationship between Th1/Th2 cytokine patterns and the arthritogenic response in collagen-induced arthritis. European Journal of Immunology, 26, 1511-1518.
9. Mosmann, T.R., Cherwinski, H., Bond, W., Giedlin, M.A. & Coffman, R.L. (1986) Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. Journal of Immunology, 136, 2348-2357.
10. Paul, W.E. & Seder, R.A. (1994) Lymphocyte response and cytokines. Cell, 76, 241-251.
11. H2 subset: doubt no more. Immunology Today, 12, 256-257.
12. - T cells produced IL-4. Journal of Immunology. 149, 1211-1215.