Role of human leukocyte interferon-α in the treatment of patients with polycythemia vera

American Journal of the Medical Sciences

Volumn 315, Issue 4, 1998, Pages 237-241

  Stasi, Roberto ^a   Venditti, Adriano ^b   Del Poeta, Giovanni ^b   Conforti, Marina ^b   Brunetti, Maurizio ^a   Bussa, Stefano ^a   Amadori, Sergio ^b   Pagano, Adalberto ^a  

^a REGINA APOSTOLORUM HOSPITAL   (Italy)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

Human leukocyte interferon ; Polycythemia vera; Pruritus

Indexed keywords

ALPHA INTERFERON A;

ADULT; ARTICLE; CELL TRANSFORMATION; CLINICAL ARTICLE; DOSE CALCULATION; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; ERYTHROCYTE VOLUME; FEMALE; HUMAN; LEUKOCYTE COUNT; MALE; MYELOPROLIFERATIVE DISORDER; PHLEBOTOMY; POLYCYTHEMIA VERA; SPLENOMEGALY;

EID: 0031978967     PISSN: 00029629     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000441-199804000-00004     Document Type: Article

References (20)

1. Berlin NI. Diagnosis and classification of the polycythemias. Semin Hematol. 1975;12:339-51.
2. Gruppo Italiano Studio Policitemia. Polycythemia vera: The natural history of 1213 patients followed for 20 years. Ann Intern Med. 1995;123:656-64.
3. Berk PD, Goldberg JD, Donovan PB, Fruchtman SM, Berlin NI, Wasserman LR. Therapeutic recommendations in polycythemia vera based on Polycythemia Vera Study Group protocols. Semin Hematol. 1986;23:132-143.
4. Silver RT. Interferon-α2b: A new treatment for polycythemia vera. Ann Intern Med. 1993;119:1091-2.
5. Cacciola E, Giustolisi R, Guglielmo P, Raimondo FD, Cacciola E, Calogero RD. Recombinant interferon-alpha in the treatment of polycythemia vera. Blood. 1991;77:2790.
6. Turri D, Mitra ME, Di Trapani R, Lipari MG, Perricone R, Cajozzo A. Alpha-interferon in polycythemia vera and essential thrombocythemia. Haematologica. 1991;76:75-7.
7. Papineschi F, Bucalossi A, Capochiani E, Benedetti E, Bramanti E, Dastoli G, et al. Recombinant alpha-2a interferon and polycythemia vera: Clinical results and biological evaluation by means of Fourier-transform infrared microspectroscopy. Eur J Haematol. 1994;53:213-7.
8. Foa P, Massaro P, Ribera S, Iurlo A, Mezzanotte C, Giandalia D, et al. Role of interferon alpha-2a in the treatment of polycythemia vera. Am J Hematol. 1995;48:55-7.
9. Taylor PC, Dolan G, Ng JP, Paul B, Collin R, Reilly JT. Efficacy of recombinant interferon alpha (rIFN-α) in polycythaemia vera: A study of 17 patients and an analysis of published data. Br J Haematol. 1996;92:55-9.
10. Cimino R, Rametta V, Matera C, Mele G, Mettivier V, Ferrara F. Recombinant interferon alpha-2b in the treatment of polycythemia vera. Am J Hematol. 1993;44:155-7.
11. Ariad S, Bezwoda WW. a-Interferon for polycythemia vera. Blood. 1991;77:670.
12. de Wolf JT, Hendriks DW, Egger RC, Esselink MT, Halie MR, Vellenga E. Alpha-interferon for intractable pruritus in polycythaemia vera. Lancet. 1991;26;337-341.
13. Finelli C, Gugliotta L, Gamberi B, Vianelli N, Visani G, Tura S. Relief of intractable pruritus in polycythemia vera with recombinant interferon alfa. Am J Hematol. 1993;43:316-8.
14. Muller EW, de Wolf JT, Egger R, Wijermans PW, Huijgens PC, Halie MR, et al. Long-term treatment with interferon alpha-2b for severe pruritus in patients with polycythaemia vera. Br J Haematol. 1995;89:313-8.
15. Cooper MR. A review of the clinical studies of alpha-interferon in the management of multiple myeloma. Semin Oncol. 1991;18(Suppl. 7):18-29.
16. Stasi R, Brunetti M, Bussa S, Venditti A, Del Poeta G, Conforti M, et al. Efficacy and safety of human leucocyte interferon-alpha treatment in patients younger than 60 years of age with polycythaemia vera. J Intern Med. 1997;242:143-7.
17. Silver RT. Interferon alfa: Effects of long-term treatment for polycythemia vera. Semin Hematol. 1997;34:40-50.
18. Salem HH, Van der Weyden MB, Young IF, Wiley DS. Pruritus and severe iron deficiency in polycythaemia. Br Med J. 1982;285:91-2.
19. Hino M, Futami E, Okuno S, Miki T, Nishizawa Y, Morii H. Possible selective effects of interferon alpha-2b on a malignant clone in a case of polycythemia vera. Ann Hematol. 1993;66:61-2.
20. Messora C, Bensi L, Vecchi A, Longo R, Giacobbi F, Temperani P, et al. Cytogenetic conversion in a case of polycythaemia vera treated with interferon-alpha. Br J Haematol. 1994;86:402-4.