The ortho-quinone metabolite of the anticancer drug etoposide (VP-16) is a potent inhibitor of the topoisomerase II/DNA cleavable complex

Molecular Pharmacology

Volumn 53, Issue 3, 1998, Pages 422-428

  Gantchev, Tsvetan G ^a,b   Hunting, Darel J ^a  

^a UNIVERSITÉ DE SHERBROOKE   (Canada)

^b UNIVERSITY OF SHERBROOKE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE (ATP HYDROLYSING); EPIPODOPHYLLOTOXIN; ETOPOSIDE; GLUTATHIONE; GLUTATHIONE DISULFIDE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CYTOTOXICITY; DNA CLEAVAGE; ENZYME ACTIVITY; ENZYME INACTIVATION; PRIORITY JOURNAL;

EID: 0031978752     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.53.3.422     Document Type: Article

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