Prothrombin fragment 1+2 is a risk factor for myocardial infarction in treated hypertensive men

Journal of Hypertension

Volumn 16, Issue 4, 1998, Pages 537-541

  Agewall, Stefan ^a   Wikstrand, John ^b   Fagerberg, Björn ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

C reactive protein; Coagulation; Coronary; Fibrinolysis; Hypertension; Myocardial infarction

Indexed keywords

ANTITHROMBIN; C REACTIVE PROTEIN; FIBRINOGEN; PLASMINOGEN ACTIVATOR INHIBITOR; PROTHROMBIN; THROMBIN; VON WILLEBRAND FACTOR;

ADULT; AGED; ARTICLE; CARDIOVASCULAR RISK; CONTROLLED STUDY; HEART INFARCTION; HEMOSTASIS; HUMAN; HYPERTENSION; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK FACTOR;

EID: 0031978716     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004872-199816040-00016     Document Type: Article

References (22)

1. Wilhelmsen L, Svärdsudd K, Korsan-Bengtsen K, Larsson B, Welin L, Tibblin G. Fibrinogen as a risk factor for stroke and myocardial infarction: the study of men born in 1913. N Engl J Med 1984; 311:501-505.
2. Kannel WB, Wolf PA, Castelli WP, D'Agostini RB. Fibrinogen and risk of cardiovascular disease. JAMA 1987; 258:1183-1186.
3. Jansson J-H, Nilsson TK, Johnson O. von Willebrand factor in plasma: a novel risk factor for recurrent myocardial infarction and death. Br Heart J 1991; 66:351-355.
4. Hamsten A, Wiman B, DeFaire U, Blombäck M. Increased plasma levels of rapid inhibitor of tissue plasminogen activator in young survivors of myocardial infarction. N Engl J Med 1985; 313:1557-1563.
5. Aznar J, Estelles A, Tormo G, Sapena P, Tormo V, Blanch S, et al. Plasminogen activator inhibitor activity and other fibrinolytic variables in patients with coronary artery disease. Br Heart J 1988; 59:535-541.
6. Paramo JA, Colucci M, Collen D, van de Werf F. Plasminogen activator inhibitor in the blood of patients with coronary artery disease. BMJ 1985; 291:573-576.
7. Kienast J, Thompson SG, Raskino C, Pelzer H, Fechtrup C, Osterman H, et al. Prothrombin fragment 1+2 and thrombin antithrombin III complexes in patients with angina pectoris: relations to the presence and severity of coronary atherosclerosis. Thromb Haemost 1993; 70:550-553.
8. Agewall S, Wikstrand J, Suurküla M, Tengborn L, Fagerberg B. Carotid artery wall morphology, hemostatic factors and cardiovascular disease: an ultrasound study in men at high and low risk for atherosclerotic disease. Blood Coag Fibrinol 1994; 5:895-904.
9. Agewall S, Wikstrand J, Wendelhag I, Tengborn L, Fagerberg B. Femoral artery wall morphology, haemostatic factors and intermittent claudication: an ultrasound study in hypertensive and normotensive men. Haemostasis 1996; 26:45-57.
10. Agewall S, Samuelsson O, Andersson OK, Persson B, Wikstrand J, Fagerberg B. The efficacy of multiple risk factor intervention in treated hypertensive men, during long term follow-up. J Intern Med 1994; 236:651-659.
11. WHO Study Group. Diabetes mellitus. Geneva: WHO; 1980.
12. Wilhelmsen L, Berglund G, Elmfeldt D, Tibblin G, Wedel H, Pennert K, et al. Manifestations in the carotid artery in high risk hypertensives. Arterioscler Thromb 1994; 14:1297-1304.
13. Suurkula M, Agewall S, Fagerberg B, Wendelhag I, Widgren B, Wikstrand J. Ultrasound evaluation of atherosclerotic manifestations in the carotid artery in high-risk hypertensive patients. Arterioscler Thromb 1994; 14:1297-1304.
14. Beckman Suurküla M, Wikstrand J, Berglund G, Sivertsson R. Body weight is more important than family history of hypertension for left ventricular function. Hypertension 1991; 17:661-668.
15. Rose GA, Blackburn H. Cardiovascular survey methods. Geneva: WHO; 1968.
16. Nilsson IM, Olow B. Determination of fibrinogen and fibrinogenolytic activity. Thromb Diath Haemorrh 1962; 8:297-309.
17. De Buyzere M, Philippe J, Duprez PD, Baele G, Clement DL. Coagulation system activation and increase of D-dimer levels in peripheral arterial occlusive disease. Am J Hematol 1993; 43:91-94.
18. Merlini PA, Ardissino D, Oltrona L, Broccolino M, Coppola R, Mannucci PM. Heightened thrombin formation but normal levels of activated factor VII in patients with acute coronary syndromes. Arterioscler Thromb Vasc Biol 1995; 15:1675-1679.
19. Heinrich J, Schulte H, Schönfeld R, Köhler E, Assman G. Association of variables of coagulation, fibrinolysis and acute-phase with atherosclerosis in coronary and peripheral arteries and those arteries supplying the brain. Thromb Haemost 1995; 73:374-379.
20. Liuzzo G, Luigi M, Biasucci L, Pepys M. The prognostic value of C-reactive protein and serum amyloid A protein in severe unstable angina. N Engl J Med 1994; 331:417-424.
21. Thompson SG, Kienast J, Pyke SDM, Haverkate F, van de Loo JCV, for the ECAT group. N Engl J Med 1995; 332:635-641.
22. Hamsten A, Blombäck M, Wiman B, Svensson J, Szamosi A, DeFaire U, et al. Haemostatic function in myocardial infarction. Br Heart J 1986; 55:58-66.