Influence of myocardial ischemia and reperfusion on β-adrenoceptor subtype expression

Journal of Cardiovascular Pharmacology

Volumn 31, Issue 4, 1998, Pages 484-487

  Bartels, Laura A ^a,d   Clifton, G Dennis ^a,b   Szabo, Tibor S ^a,c  

^a UNIVERSITY OF KENTUCKY   (United States)

^b WASHINGTON STATE UNIVERSITY   (United States)

^c Memphis Lung Physicians   (United States)

^d ALBANY COLLEGE OF PHARMACY AND HEALTH SCIENCES   (United States)

Author keywords

Adrenoceptor; Canine; Ischemia; Myocardium; Reperfusion

Indexed keywords

BETA ADRENERGIC RECEPTOR; CYANOPINDOLOL I 125; RECEPTOR SUBTYPE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY LIGATION; DOG; DRUG RECEPTOR BINDING; FEMALE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; ISOTOPE LABELING; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RECEPTOR DENSITY;

ANIMALS; CORONARY DISEASE; CORONARY VESSELS; DOGS; FEMALE; MALE; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; RECEPTORS, ADRENERGIC, BETA-1; RECEPTORS, ADRENERGIC, BETA-2;

EID: 0031978123     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199804000-00002     Document Type: Article

References (16)

1. Opie LH, Nathan D, Lubbe WF. Biochemical aspects of arrhythmogenesis and ventricular fibrillation. Am J Cardiol 1979; 43:131-48.
2. Yusuf S, Peto R, Lewis J, Collins R, Sleight P. Beta blockade during and after myocardial infarction: an overview of the randomized trials. Prog Cardiovasc Dis 1985;27:335-71.
3. Mukherjee A, Wong TM, Juja M, Lefkowitz RJ, Willerson JT. Beta adrenergic and muscurinic cholinergic receptors in canine myocardium. J Clin Invest 1979;64:1423-8.
4. Ohyanagi M, Matsumori Y, Iwasaki T. Beta-adrenergic receptors in ischemic and nonischemic canine myocardium: relation to ventricular fibrillation and effects of pretreatment with propranolol and hexamethonium. J Cardiovasc Pharmacol 1988;11:107-14.
5. Strasser RH, Marquetant R, Kubler W. Independent sensitization of β-adrenoceptors and adenylate cyclase in acute myocardial ischemia. Br J Clin Pharmacol 1990;30:27S-35S.
6. Maisel AS, Motulsky HJ, Ziegler MG, Insel PA. Ischemia and agonist induced changes in alpha and beta adrenergic receptor traffic in guinea pig hearts. Am J Physiol 1987;253:H1159-66.
7. Maisel AS, Motulsky HJ, Insel PA. Externalization of β-adrenergic receptors promoted by myocardial ischemia. Science 1985;230: 183-6.
8. 1-receptor down-regulation in heart failure. Circ Res 1986;59:297-309.
9. Thandroyen FT, Muntz K, Rosenbaum T, Ziman B, Willerson JT, Buja LM. β-receptor-adenylate cyclase coupling in hypoxic neonatal rat ventricular myocytes. Am J Physiol 1989:H1209-17.
10. Karliner JS, Stevens MB, Honbo N, Hoffman JIE. Effects of acute ischemia in the dog on myocardial blood flow, beta receptors, and adenylate cyclase activity with and without chronic beta blockade. J Clin Invest 1989;83:474-81.
11. Devos C, Robberecht P, Nokin P, et al. Uncoupling between beta-adrenoceptors and adenylate cyclase in dog ischemic myocardium. Naunyn Schmiedebergs Arch Pharmacol 1885;331:71-5.
12. Xiaoyan L, Barnett DB. Differential rates of down regulation and recovery of rat myocardial β-adrenoceptor subtypes in vivo. Eur J Pharmacol 1990;182:481-6.
13. 1-receptor downregulation in heart failure. Circ Res 1986;59:297-309.
14. 1-adrenergic receptors. J Mol Cell Cardiol 1995;27:437-52.
15. 2-adrenergic receptors in rat heart and lung in vitro. Mol Pharmacol 1979;16:21-3.
16. Eichhorn EJ, Hjalmarson A. β-Blocker treatment for chronic heart failure: the frog prince. Circulation 1994;90:2153-6.