The 102-kilobase unstable region of Yersinia pestis comprises a high- pathogenicity island linked to a pigmentation segment which undergoes internal rearrangement

Journal of Bacteriology

Volumn 180, Issue 9, 1998, Pages 2321-2329

  Buchrieser, Carmen ^a   Prentice, Michael ^a,b   Carniel, Elisabeth ^a  

^a INSTITUT PASTEUR   (France)

^b ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACTERIAL GENE; BACTERIAL VIRULENCE; GENE ISOLATION; GENE LOCUS; GENE REARRANGEMENT; NONHUMAN; PIGMENTATION; PRIORITY JOURNAL; YERSINIA ENTEROCOLITICA;

ANIMALIA; BACTERIA (MICROORGANISMS); NEGIBACTERIA; YERSINIA ENTEROCOLITICA; YERSINIA PESTIS;

EID: 0031977363     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.180.9.2321-2329.1998     Document Type: Article

References (48)

1. Bearden, S. W., J. D. Fetherston, and R. D. Perry. 1997. Genetic organization of the yersiniabactin biosynthetic region and construction of avirulent mutants in Yersinia pestis. Infect. Immun. 65:1659-1668.
2. Birnboim, H. C., and J. Doly. 1979. A rapid alkaline extraction procedure for screening recombinant plasmid DNA. Nucleic Acids Res. 7:1513-1523.
3. Blum, G., M. Ott, A. Lischewski, A. Ritter, H. Imrich, H. Tschäpe, and J. Hacker. 1994. Excision of large DNA regions termed pathogenicity islands from tRNA-specific loci in the chromosome of an Escherichia coli wild-type pathogen. Infect. Immun. 62:606-614.
4. Buchrieser, C., O. Buchrieser, A. Kristl, and C. W. Kaspar. 1994. Clamped homogeneous electric fields (CHEF) gel-electrophoresis of DNA restriction fragments for comparing genomic variations among strains of Yersinia enterocolitica and Yersinia spp. Zentralbl. Bakteriol. 281:457-470.
5. Carniel, E., I. Guilvout, and M. Prentice. 1996. Characterization of a large chromosomal "high-pathogenicity island" in biotype 1B Yersinia enterocolitica. J. Bacteriol. 178:6743-6751.
6. Carniel, E., A. Guiyoule, I. Guilvout, and O. Mercereau-Puijalon. 1992. Molecular cloning, iron-regulation and mutagenesis of the irp2 gene encoding HMWP2, a protein specific for the highly pathogenic Yersinia. Mol. Microbiol. 6:379-388.
7. Carniel, E., A. Guiyoule, O. Mercereau-Puijalon, and H. H. Mollaret. 1991. Chromosomal marker for the high pathogenicity phenotype in Yersinia. Contrib. Microbiol. Immunol. 12:192-197.
8. Carniel, E., O. Mercereau-Puijalon, and S. Bonnefoy. 1989. The gene coding for the 190,000-dalton iron-regulated protein of Yersinia species is present only in the highly pathogenic strains. Infect. Immun. 57:1211-1217.
9. Censini, S., C. Lange, Z. Xiang, J. E. Crabtree, P. Ghiara, M. Borodovsky, R. Rappuoli, and A. Covacci. 1996. cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors. Proc. Natl. Acad. Sci. USA 93:14648-14653.
10. Cheetham, B. F., and M. E. Katz. 1995. A role for bacteriophages in the evolution and transfer of bacterial virulence determinants. Mol. Microbiol. 18:201-208.
11. De Almeida, A. M. P., A. Guiyoule, I. Guilvout, I. Iteman, G. Baranton, and E. Carniel. 1993. Chromosomal irp2 gene in Yersinia: distribution, expression, deletion and impact on virulence. Microb. Pathog. 14:9-21.
12. De Almeida, A. M. P., A. Guiyoule, N. C. Leal, and E. Carniel. 1994. Survey of the irp2 gene among Yersinia pestis strains isolated during several plague outbreaks in Northeast Brazil. Mem. Inst. Oswaldo Cruz 89:87-92.
13. Devignat, R. 1951. Variétés de l'espèce Pasteurella pestis. Nouvelle hypothèse. Bull. Org. Mond. Santé 4:247-263.
14. Fetherston, J. D., S. W. Bearden, and R. D. Perry. 1996. YbtA, an AraC-type regulator of the Yersinia pestis pesticin/yersiniabactin receptor. Mol. Microbiol. 22:315-325.
15. Fetherston, J. D., J. W. Lillard, Jr., and R. D. Perry. 1995. Analysis of the pesticin receptor from Yersinia pestis: role in iron-deficient growth and possible regulation by its siderophore. J. Bacteriol. 177:1824-1833.
16. + is flanked by an insertion sequence and includes the structural genes for pesticin sensitivity and HMWP2. Mol. Microbiol. 13:697-708.
17. Fetherston, J. D., P. Schuetze, and R. D. Perry. 1992. Loss of the pigmentation phenotype in Yersinia pestis is due to the spontaneous deletion of 102 kb of chromosomal DNA which is flanked by a repetitive element. Mol. Microbiol. 6:2693-2704.
18. Filippov, A. A., P. N. Oleinikov, V. L. Motin, O. A. Protsenko, and G. B. Smirnov. 1995. Sequencing of two Yersinia pestis IS elements, IS285, and IS100. Contrib. Microbiol. Immunol. 13:306-309.
19. Forsberg, Ä., and H. Wolf-Watz. 1990. Genetic analysis of the yopE region of Yersinia spp.: identification of a novel conserved locus. yerA, regulating yopE expression. J. Bacteriol. 172:1547-1555.
20. Guilvout, I., O. Mercereau-Puijalon, S. Bonnefoy, A. P. Pugsley, and E. Carniel. 1993. High-molecular-weight protein 2 of Yersinia enterocolitica is homologous to AngR of Vibrio anguillarum and belongs to a family of proteins involved in nonribosomal peptide synthesis. J. Bacteriol. 175:5488-5504.
21. Guiyoule, A., F. Grimont, I. Iteman, P. A. D. Grimont, M. Lefevre, and E. Carniel. 1994. Plague pandemics investigated by ribotyping of Yersinia pestis strains. J. Clin. Microbiol. 32:634-641.
22. Guiyoule, A., B. Rasoamanana, C. Buchrieser, P. Michel, S. Chanteau, and E. Carniel. 1997. Recent emergence of new variants of Yersinia pestis in Madagascar. J. Clin. Microbiol. 35:2826-2833.
23. Hacker, J., L. Bender, J. Wingender, B. Lund, R. Marre, and W. Goebel. 1990. Deletions of chromosomal regions coding for fimbriae and haemolysins occur in vitro and in vivo in various extraintestinal Escherichia coli isolates. Microb. Pathog. 8:213-225.
24. Hacker, J., G. Blum-Oehler, I. Mühldorfer, and H. Tschäpe. 1997. Pathogenicity islands of virulent bacteria: structure, function and impact on microbial evolution. Mol. Microbiol. 23:1089-1097.
25. Heesemann, J. 1987. Chromosomal-encoded siderophores are required for mouse virulence of enteropathogenic Yersinia species. FEMS Microbiol. Lett. 48:229-233.
26. Hinnebusch, B. J., R. D. Perry, and T. G. Schwan. 1996. Role of the Yersinia pestis hemin storage (hms) locus in the transmission of plague by fleas. Science 273:367-370.
27. Iteman, I., A. Guiyoule, A. M. P. de Almeida, I. Guilvout, G. Baranton, and E. Carniel. 1993. Relationship between loss of pigmentation and deletion of the chromosomal iron-regulated irp2 gene in Yersinia pestis: evidence for separate but related events. Infect. Immun. 61:2717-2722.
28. Kao, J.-S., D. Stucker, J. W. Warren, and H. L. Mobley. 1997. Pathogenicity island sequences of pyelonephritic Escherichia coli CFT073 are associated with virulent uropathogenic strains. Infect. Immun. 65:2812-2820.
29. Kovach, M. E., M. D. Shefter, and K. M. Peterson. 1996. A putative integrase gene defines the distal end of a large cluster of ToxR-regulated colonization genes in Vibrio cholerae. Microbiology 142:2165-2174.
30. Kutyrev, V. V., A. A. Filippov, O. S. Oparina, and O. A. Protsenko. 1992. Analysis of Yersinia pestis chromosomal determinants Pgm(+) and Pst(s) associated with virulence. Microb. Pathog. 12:177-186.
31. Lillard, J. W., Jr., J. D. Fetherston, L. Pedersen, M. L. Pendrak, and R. D. Perry. 1997. Sequence and genetic analysis of the hemin storage (Hms) system of Yersinia pestis. Gene 193:13-21.
32. Lucier, T. S., and R. R. Brubaker. 1992. Determination of genome size, macrorestriction pattern polymorphism, and nonpigmentation-specific deletion in Yersinia pestis by pulsed-field gel electrophoresis. J. Bacteriol. 174: 2078-2086.
33. McDaniel, T. K., K. G. Jarvis, M. S. Donnenberg, and J. B. Kaper. 1995. A genetic locus of enterocyte effacement conserved among diverse enterobacterial pathogens. Proc. Natl. Acad. Sci. USA 92:1664-1668.
34. Miller, V. L., J. B. Bliska, and S. Falkow. 1990. Nucleotide sequence of the Yersinia enterocolitica ail gene and characterization of the Ail protein product. J. Bacteriol. 172:1062-1069.
35. Mills, D. M., V. Bajaj, and C. A. Lee. 1995. A 40 kb chromosomal fragment encoding Salmonella typhimurium invasion genes is absent from the corresponding region of the Escherichia coli K-12 chromosome. Mol. Microbiol. 15:749-759.
36. + phenotype of Yersinia pestis. Mol. Microbiol. 8:857-864.
37. Perry, R. D., and J. D. Fetherston. 1997. Yersinia pestis - etiologic agent of plague. Clin. Microbiol. Rev. 10:35-66.
38. Perry, R. D., M. L. Pendrak, and P. Schuetze. 1990. Identification and cloning of a hemin storage locus involved in the pigmentation phenotype of Yersinia pestis. J. Bacteriol. 172:5929-5937.
39. Podladchikova, O. N., G. G. Dikhanov, A. V. Rakin, and J. Heesemann. 1994. Nucleotide sequence and structural organization of Yersinia pestis insertion sequence IS100. FEMS Microbiol. Lett. 121:269-274.
40. Rakin, A., and J. Heesemann. 1995. The established Yersinia pestis biovars are characterized by typical patterns of I-CeuI restriction fragment length polymorphism. Mol. Genet. Mikrobiol. Virusol. 3:26-29.
41. Rakin, A., and J. Heesemann. 1995. Virulence-associated fyuA/irp2 gene cluster of Yersinia enterocolitica biotype 1B carries a novel insertion sequence, IS1328. FEMS Microbiol. Lett. 129:287-292.
42. Rakin, A., E. Saken, D. Harmsen, and J. Heesemann. 1994. The pesticin receptor of Yersinia enterocolitica: a novel virulence factor with dual function. Mol. Microbiol. 13:253-263.
43. Schubert, S., A. Rakin, H. Karch, E. Carniel, and J. Heesemann. 1998. Prevalence of the "high-pathogenicity island" of Yersinia species among Escherichia coli strains that are pathogenic to humans. Infect. Immun. 66:480-485.
44. Shea, J. E., M. Hensel, C. Gleeson, and D. W. Holden. 1996. Identification of a virulence locus encoding a second type III secretion system in Salmonella typhimurium. Proc. Natl. Acad. Sci. USA 93:2593-2597.
45. Simonet, M., B. Riot, N. Fortineau, and P. Berche. 1996. Invasin production by Yersinia pestis is abolished by insertion of an IS200-like element within the inv gene. Infect. Immun. 64:375-379.
46. Skurnik, M., and P. Toivanen. 1991. Intervening sequences (IVSs) in the 23S ribosomal RNA genes of pathogenic Yersinia enterocolitica strains - the IVSs in Y. enterocolitica and Salmonella typhimurium have a common origin. Mol. Microbiol. 5:585-593.
47. Surgalla, M. J., and E. D. Beesley. 1969. Congo red-agar plating medium for detecting pigmentation in Pasteurella pestis. Appl. Microbiol. 18:834-837.
48. Swenson, D. L., N. O. Bukanov, D. E. Berg, and R. A. Welch. 1996. Two pathogenicity islands in uropathogenic Escherichia coli J96: cosmid cloning and sample sequencing. Infect. Immun. 64:3736-3743.