The rubella virus nonstructural protease requires divalent cations for activity and functions in trans

Journal of Virology

Volumn 72, Issue 5, 1998, Pages 4463-4466

  Liu, Xin ^a   Ropp, Susan L ^a   Jackson, Richard J ^b   Frey, Teryl K ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE PROTEINASE; VIRUS ENZYME;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATION EXCHANGE; ENZYME STRUCTURE; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RABBIT; RETICULOCYTE LYSATE; RUBELLA VIRUS; VIRUS MUTATION;

EID: 0031977295     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.5.4463-4466.1998     Document Type: Article

References (23)

1. Agranovsky, A. A., E. V. Koonin, V. P. Boyko, E. Maiss, R. Frotschl, N. A. Lunina, and J. G. Atabekov. 1994. Beet yellows closterovirus: complete genome structure and identification of a leader papain-like thiol protease. Virology 198:311-324.
2. Bonilla, P. J., S. A. Hughes, and S. R. Weiss. 1997. Characterization of a second cleavage site and demonstration of activity in trans by the papain-like proteinase of the murine coronavirus mouse hepatitis virus A59. J. Virol. 71:900-909.
3. Bransom, K. L., and T. W. Dreher. 1994. Identification of the essential cysteine and histidine residues of the turnip yellow mosaic virus protease. Virology 198:148-154.
4. Carrington, J. C., D. D. Freed, and T. C. Sanders. 1989. Autocatalytic processing of the potyvirus helper component proteinase in Escherichia coli and in vitro. J. Virol. 63:4459-4463.
5. Chen, J.-P., J. H. Strauss, E. G. Strauss, and T. K. Frey. 1996. Characterization of the rubella virus nonstructural protease and its cleavage site. J. Virol. 70:4707-4713.
6. Choi, G. H., D. M. Pawlyk, and D. L. Nuss. 1991. The autocatalytic protease p29 encoded by a hypovirulence-associated virus of the chestnut blight fungus resembles the potyvirus-encoded protease HC-Pro. Virology 183:747-752.
7. Den Boon, J. A., K. S. Faaberg, J. J. M. Meulenberg, A. L. M. Wassenaar, P. G. W. Plagemann, A. E. Gorbalenya, and E. J. Snijder. 1995. Processing and evolution of the N-terminal region of the arterivirus replicase ORF1a protein: identification of two papainlike cysteine proteases. J. Virol. 69:4500-4505.
8. Dominguez, G. 1991. Determination and analysis of the sequence of the genome RNA of rubella virus. Ph.D. dissertation. Georgia State University, Atlanta.
9. Forng, R.-Y., and T. K. Frey. 1995. Identification of the rubella virus non-structural proteins. Virology 206:843-853.
10. Frey, T. K. 1994. Molecular biology of rubella virus. Adv. Virus Res. 44:69-160.
11. Gorbalenya, A. E., E. V. Koonin, and M. M.-C. Lai. 1991. Putative papain-related thiol proteases of positive-strand RNA viruses. FEBS Lett. 288:201-205.
12. Hardy, W. R., and J. H. Strauss. 1989. Processing the nonstructural polyproteins of Sindbis virus: nonstructural protease is in the C-terminal half of nsP2 and functions both in cis and in trans. J. Virol. 62:998-1007.
13. Jackson, R. J., and T. Hunt. 1983. Preparation and use of nuclease-treated rabbit reticulocyte lysates for the translation of eukaryotic messenger RNA. Methods Enzymol. 96:50-74.
14. Kirchweger, R., E. Ziegler, B. J. Lamphear, D. Waters, H.-D. Liebig, W. Sommergruber, F. Sobrino, C. Hohenadl, D. Blaas, R. E. Rhoads, and T. Skern. 1994. Foot-and-mouth disease virus leader proteinase: purification of the Lb form and determination of its cleavage site on eIF-4-γ. J. Virol. 68:5677-5684.
15. Lawrence, D. M., M. N. Rozanov, and B. I. Hillman. 1995. Autocatalytic processing of the 223 kDa protein of blueberry scorch carlavirus by a papainlike protease. Virology 207:127-135.
16. Marr, L. D., C.-Y. Wang, and T. K. Frey. 1994. Expression of the rubella virus nonstructural protein ORF and demonstration of proteolytic processing. Virology 198:586-592.
17. Pugachev, K. V., E. S. Abernathy, and T. K. Frey. 1997. Genomic sequence of the RA27/3 vaccine strain of rubella virus. Arch. Virol. 142:1165-1180.
18. Rice, C. M., R. Levis, J. H. Strauss, and H. V. Huang. 1987. Production of infectious RNA transcripts from Sindbis virus cDNA clones: mapping of lethal mutations, rescue of a temperature-sensitive marker, and in vitro mutagenesis to generate denned mutants. J. Virol. 61:3809-3819.
19. Shapira, R., and D. L. Nuss. 1991. Gene expression by a hypovirulence-associated virus of the chestnut blight fungus involves 2 papain-like proteinase activities: essential residues and cleavage site requirements for P48 autoproteolysis. J. Biol. Chem. 266:19419-19425.
20. Snijder, E. J., A. L. M. Wassenaar, and W. J. M. Spaan. 1994. Proteolytic processing of the replicase ORF1a protein of equine arteritis virus. J. Virol. 68:5755-5764.
21. Stempniak, M., Z. Hostomoska, B. R. Nodes, and Z. Hostomsky. 1997. The NS3 protease domain of hepatitis C virus is a zinc-containing enzyme. J. Virol. 71:2881-2886.
22. Tibbies, K. W., I. Brierley, D. Cavanagh, and T. D. K. Brown. 1996. Characterization in vitro of an autocatalytic processing activity associated with the predicted 3C-like protease domain of the coronavirus avian infectious bronchitis virus. J. Virol. 70:1923-1930.
23. Wang, C.-Y., G. Dominguez, and T. K. Frey. 1994. Construction of rubella virus genome-length cDNA clones and synthesis of infectious RNA transcripts. J. Virol. 68:3550-3557.