Prophylaxis of acute osteomyelitis with absorbable ofloxacin-impregnated beads

Antimicrobial Agents and Chemotherapy

Volumn 42, Issue 4, 1998, Pages 840-842

  Nicolau, David P ^a   Nie, Lin ^a,b   Tessier, Pamela R ^a   Kourea, Helen P ^a   Nightingale, Charles H ^a  

^a HARTFORD HOSPITAL   (United States)

^b SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

OFLOXACIN; POLYMER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC PROPHYLAXIS; ARTICLE; BACTERIUM CULTURE; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; NONHUMAN; ORTHOPEDIC SURGERY; OSTEOMYELITIS; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS;

EID: 0031977159     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.42.4.840     Document Type: Article

References (19)

1. Buchholz, H. W., and E. Engelbrecht. 1970. Uber die depotwirkung einiger antibiotika bei vermischung mit dem Kunstharz Palaco. Chirurg 41:511-515.
2. Dich, V. Q., J. D. Nekson, and K. C. Haltalin. 1975. Osteomyelitis in infants and children. Am. J. Dis. Child. 129:1273-1278.
3. Gerszien, E., M. J. Allison, and H. P. Dalton. 1970. An epidemiologic study of 100 consecutive cases of osteomyelitis. South. Med. J. 63:365.
4. Gilmour, W. N. 1962. Acute hematogenous osteomyelitis. J. Bone Jt. Surg. Br. Vol. 44:842.
5. Hamblen, D. L. 1968. Hyperbaric oxygenation: its effects on experimental staphylococcal osteomyelitis in rats. J. Bone Jt. Surg. Am. Vol. 50:1129-1141.
6. Ikada, Y., S.-H. Huon, and K. Jamshidi. 1985. Release of antibiotics from composites of hydroxyapatite and poly(lactic acid). J. Control. Release 2: 179-186.
7. Klepser, M. E., K. B. Patel, D. P. Nicolau, R. Quintiliani, and C. H. Nightingale. 1995. Comparison of the bactericidal activities of ofloxacin and ciprofloxacin alone or in combination with ceftazidime and piperacillin against clinical strains of Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 39:2503-2510.
8. Morrissy, R. T., and D. W. Haynes. 1989. Acute hematogenous osteomyelitis: a model with trauma as an etiology. J. Pediatr. Orthop. 9:447-456.
9. National Institutes of Health. 1985. Guide for the care and use of laboratory animals. National Institutes of Health publication no. 85-23. U.S. Department of Health and Human Services, Washington, D.C.
10. Nelson, J. P. 1977. Deep infection following total hip arthroplasty. J. Bone Jt. Surg. Am. Vol. 59:1042.
11. Nie, L., D. P. Nicolau, C. H. Nightingale, and B. D. Browner. 1995. The in vitro elution of ofloxacin from a bioabsorbable polymer. Acta Orthop. Scand. 66:365-368.
12. Petty, W., and S. Goldsmith. 1980. Resection arthroplasty following infected total hip arthroplasty. J. Bone Jt. Surg. Am. Vol. 62:889.
13. Reichelt, A., H. Wahlig, and H. Riedlk. 1976. Antibiotic prophylaxis in allo-arthroplastic hip joint surgery. Arch. Orthop. 84:249-255.
14. Riegels-Nielsen, P., F. Espersen, L. R. Holmich, and N. Frimodt-Moller. 1995. Collagen with gentamicin for prophylaxis of postoperative infection. Acta Orthop. Scand. 66:69-72.
15. Rodeheaver, G. T., D. Rukstalis, M. Bono, and W. Bellamy. 1983. A new model of bone infection used to evaluate the efficacy of antibiotic-impregnated polymethylmethacrylate cement. Clin. Orthop. 178:303-311.
16. Sahm, D. F., and J. A. Washington II. 1991. Antibacterial susceptibility tests: dilution methods, p. 1105-1116. In A. Balows, W. J. Hausler, Jr., K. L. Herrmann, H. D. Isenberg, and H. J. Shadomy (ed.), Manual of clinical microbiology. 5th ed. American Society for Microbiology, Washington, D.C.
17. Visscher, G. E., R. L. Robinson, H. V. Maulding, J. W. Fong, J. E. Pearson, and G. J. Argentieri. 1985. Biodegradation of and tissue reaction to 50:50 poly (DL-lactide-co-glycolide) microcapsule. J. Biomed. Mater. Res. 19:349-355.
18. Wei, G., Y. Kotoura, M. Oka, T. Yamamuro, R. Wada, S.-H. Huon, and Y. Ikada. 1991. A bioabsorbable delivery system for antibiotic treatment of osteomyelitis. J. Bone Jt. Surg. Br. Vol. 73B:246-251.
19. Worlock, P., R. Slack, L. Harvey, and R. Mawhinney. 1988. The prevention of infection in open fractures. J. Bone Jt. Surg. Am. Vol. 70:1341-1347.