Synthesis and antihypertensive activity of 4-(diazabicyclo[4.1.0]- heptenyloxy)benzopyran Derivatives and their analogues

Chemical and Pharmaceutical Bulletin

Volumn 46, Issue 4, 1998, Pages 602-609

  Horino, Haruhiko ^a   Mimura, Tetsuya ^a   Kagechika, Katsuji ^a   Ohta, Masahiro ^a   Kubo, Hideo ^a   Kitagawa, Masayuki ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

2H 1 benzopyran; Diazabicyclo 4.1.0 heptene; Hypotensive activity; Potassium channel opener

Indexed keywords

3,4 DIHYDRO 3 HYDROXY 2,2,3 TRIMETHYL 4 [(4 METHYL 5 OXO 3,4 DIAZABICYCLO[4.1.0]HEPT 2 EN 2 YL)OXY] 2H 1 BENZOPYRAN CARBONITRILE; ANTIHYPERTENSIVE AGENT; LEMAKALIM; POTASSIUM CHANNEL; POTASSIUM CHANNEL STIMULATING AGENT; SYMAKALIM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; CHANNEL GATING; DRUG CONFORMATION; DRUG POTENCY; DRUG SYNTHESIS; HYPERTENSION; NONHUMAN; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; STRUCTURE ACTIVITY RELATION;

EID: 0031976706     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.46.602     Document Type: Article

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