Acute effects of ozone on pulmonary function of cyclists receiving antioxidant supplements

Occupational and Environmental Medicine

Volumn 55, Issue 1, 1998, Pages 13-17

  Grievink, Linda ^a,b   Jansen, Saskia M A ^a   Van't Veer, Pieter ^a   Brunekreef, Bert ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b Netherlands Inst of Health Sciences

Author keywords

Antioxidants; Lung function; Ozone

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BETA CAROTENE; OZONE;

ADOLESCENT; ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYCLING; DIET SUPPLEMENTATION; DRUG EFFECT; EXERCISE; HUMAN; HUMAN EXPERIMENT; LUNG FUNCTION; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

PHOCIDAE;

EID: 0031976361     PISSN: 13510711     EISSN: None     Source Type: Journal    
DOI: 10.1136/oem.55.1.13     Document Type: Article

References (23)

1. World Health Organisation. Acute effects on health of smog episodes. Copenhagen: WHO Regional Office for Europe, 1990.
2. Lippmann M. Health effects of ozone. A critical review. Journal of Air Pollution Control Association 1989;39:672-95.
3. Gong H Jr, Bradley PW, Simmons MS, Tashkin DP. Impaired exercise performance and pulmonary function in elite cyclists during low-level ozone exposure in a hot environment. Am Rev Respir Dis 1986;134:726-33.
4. Avol EL, Linn WS, Venet TG, Shamoo DA, Hackney JD. Comparative respiratory effects of ozone and ambient oxidant pollution exposure during heavy exercise. Journal of Air Pollution Control Association 1984;34:804-9.
5. Horstman DH, Folinsbee LJ, Ives PJ, Abdul-Salaam S, MacDonell WF. Ozone concentration and pulmonary response relationships for 6.6-hour exposures with five hours of moderate exercise to 0.08, 0.10, and 0.12 ppm. Am Rev Respir Dis 1990;142:1158-63.
6. Brunekreef B, Hoek G, Breugelmans O, Leentvaar M. Respiratory effects of low-level photochemical air pollution in amateur cyclists. Am J Respir Crit Care Med 1994;150:962-6.
7. Menzel DB. Antioxidant vitamins and prevention of lung disease. Ann N Y Acad Sci 1992;669:141-55.
8. Chatham MD, Eppler JH Jr, Saunder LR, Green D, Kulle TJ. Evaluation of the effects of vitamin C on ozone induced bronchoconstriction in normal subjects. Ann N Y Acad Sci 1987;498:269-79.
9. Hackney JD, Linn WS, Buckley RD, Jones MP, Wightman LH, Karuza SK. Vitamin E supplementation and respiratory effects of ozone in humans. J Toxicol Environ Health 1981;7:383-90.
10. 2 and other pollutants. In: Schneider T, Grant LD, eds. Air pollution by nitrogen oxides. Amsterdam: Elsevier Science Publishing, 1982;427-40.
11. Quanjer PhH. Standardized lung function testing. Bulletin Européen de Physiopathologie Respiratoire 1983;19:7-86.
12. Johnson LR, Enright PL, Voelker HT, Tashkin DP. Volume spirometers need automated internal temperature sensors. Am J Respir Crit Care Med 1994;150:1575-80.
13. SAS. SAS/STAT user's guide. Cary: SAS Institute, 1996.
14. Folinsbee LJ, Horvath SM, Raven PB, Bedi JF, Morton AR, Drinkwater BL, et al. Influence of exercise and heat stress on pulmonary function during ozone exposure. J Appl Physiol 1977;43:409-13.
15. Gibbons SI, Adams WC. Combined effects of ozone exposure and ambient heat on exercising females. J Appl Physiol 1984;57:450-6.
16. Hoek G, Fisher P, Brunekreef B, Lebret E, Hofschreuder P, Mennen MG. Acute effects of ambient ozone on pulmonary function of children in the Netherlands. Am Rev Respir Dis 1993;147:111-7.
17. Kardinaal AFM, van 't Veer P, Brants HAM, van den Berg H, van Schoonhoven J, Hermus RJJ. Relations between antioxidant vitamins in adipose tissue, plasma, and diet. Am J Epidemiol 1995;141:440 50.
18. Salonen JT, Salonen R, Seppänen K, et al. Effects of antioxidant supplementation on platelet function: a randomized pair-matched, placebo-controlled, double-blind trial in men with low antioxidant status. Am J Clin Nutr 1991;53: 1222-9.
19. London RS, Sundaram GS, Manimekalai S, Murphy L, Reynolds MA, Goldstein P. Serum α-tocopherol levels in relation to serum lipids and lipoproteins after oral administration of vitamin E. In: Prasad, ed. Vitamins nutrition and cancer. Basel: Karger, 1984;159-65.
20. Schelegle ES, Siefkin AD, McDonald RJ. Time course of ozone-induced neutrophilia in normal humans. Am Rev Respir Dis 1991;143:1353-8.
21. Hazucha MJ, Bates DV, Bromberg PA. Mechanism of action of ozone on the human lung. J Appl Physiol 1989;67:1535 41.
22. Ogilvy CS, DuBois AB, Douglas JS. Effects of ascorbic acid and indomethacin on the airways of healthy male subjects with and without induced bronchoconstriction. J Allergy Clin Immunol 1981;67:363-9.
23. Mohsenin V, DuBois AB, Douglas JS. Effect of ascorbic acid on response to methacholine challenge in asthmatic subjects. Am Rev Respir Dis 1983;127:143-7.