Virulence and colonization-associated properties of Helicobacter pylori isolated from children and adolescents

Journal of Infectious Diseases

Volumn 177, Issue 1, 1998, Pages 247-252

  Çelik, Janet ^b   Su, Bin ^b   Tirén, Urban ^b   Finkel, Yigael ^b   Thoresson, Ann Cathrin ^b   Engstrand, Lars ^b   Sandstedt, Bengt ^b   Bernander, Sverker ^b   Normark, Staffan ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL VIRULENCE; BACTERIUM ISOLATION; CHILD; CHRONIC GASTRITIS; CLINICAL ARTICLE; FEMALE; HELICOBACTER PYLORI; HUMAN; MALE; PEPTIC ULCER; PRIORITY JOURNAL; STOMACH MUCOSA;

EID: 0031975992     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/517365     Document Type: Article

References (15)

1. Blaser MJ, Chyou PH, Nomura A. Age at establishment of Helicobacter pylori infection and gastric carcinoma, gastric ulcer and duodenal ulcer risk. A birth order and sibship size study. Cancer research 1995;55: 562-5.
2. Borén T, Falk P, Roth KA, Larson G, Normark S. Attachment of Helicobacter pylori to human gastric epithelium mediated by blood group antigens. Science 1993;262:1892-5; comments in Science 1993;262: 1817 and 1994;264:1386-8.
3. b-containing glyconjugates: a potential transgenic mouse model for studying Helicobacter pylori infection. Proc Natl Acad Sci USA 1995;92:1515-9.
4. Telford JL Ghiara P, Dell'Orco M, et al. Gene structure of the Helicobacter pylori cytotoxin and evidence of its key role in gastric disease. J Exp Med 1994;179:1653-8.
5. Atherthon JC, Cao P, Peek RM Jr, Tummuru MK, Blaser MJ, Cover TL. Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. J Biol Chem 1995;270:17771-7.
6. Tummuru MKR, Cover TL, Blaser MJ. Cloning and expression of a high-molecular-mass major antigen of Helicobacter pylori: evidence of linkage to cytotoxin production. Infect Immun 1993;61:1799-809.
7. Marchetti M, Arico B, Burroni D, Figura N, Rappuoli R, Ghiara P. Development of a mouse model of Helicobacter pylori infection that mimics human disease. Science 1995;267:1658-8.
8. Tummuru MKR, Sharma AS, Blaser MJ. Helicobacter pylori picB, a homologue of the Bordetella pertussis toxin secretion, is required for induction of IL-8 in gastric epithelial cells. Mol Microbiol 1995;18: 867-76.
9. Aspinall GO, Monterio MA. Lipopolysaccharides of Helicobacter pylori strains P466 and MO19: structures of the O antigen and core oligosaccharide regions. Biochemistry 1996;35:2498-504.
10. Ashorn M, Ruuska T, Karikoski R, Miettinen A, Maki M. Helicobacter pylori gastritis in dyspeptic children. A long-term follow-up after treatment with colloidal bismuth subcitrate and tinidazole. Scand J Gastroenterol 1994;29:203-8.
11. Apley J, Naish N. Recurrent abdominal pain: a field survey of 1000 school children. Arch Dis Child 1958;33:165-70.
12. Xiang Z, Censini S, Baydi PF, et al. Analysis of expression of CagA and VacA virulence factors in 43 strains of Helicobacler pylori reveals that clinical isolates can be divided into two major types and that CagA is not necessary for expression of the vacuolating cytotoxin. Infect Immun 1995;63:94-8.
13. Cover TL, Dooley CP, Blaser MJ. Characterization of and human serologic response to proteins in Helicobacter pylori broth culture supernatants with vacuolizing cytotoxin activity. Infect Immun 1990;58:603-10.
14. Husson MO, Gottrand F, Vachee A, et al. Importance in diagnosis of gastritis of detection by PCR of the cag gene in Helicobacter pylori strains isolated from children. J Clin Microbiol 1995;33: 3300-3.
15. Blaser MJ, Perez-Perez GI, Kleanthouse C, et al. Infection with Helicobacter pylori strains possessing CagA is associated with an increased risk of developing adenocarcinoma of the stomach. Cancer Res 1995; 55:2111-5.