Imbalance between serum matrix metalloproteinase-2 and its inhibitor as a predictor of recurrence of urothelial cancer

British Journal of Cancer

Volumn 77, Issue 4, 1998, Pages 650-655

  Gohji, K ^a,b   Fujimoto, N ^c   Ohkawa, J ^a   Fujii, A ^a   Nakajima, M ^d  

^a HYOGO MEDICAL CENTER FOR ADULTS   (Japan)

^b KOBE UNIVERSITY   (Japan)

^c FUJI CHEMICAL INDUSTRIES LTD   (Japan)

^d CIBA GEIGY LTD   (Switzerland)

Author keywords

Matrix metalloproteinase 2; Recurrence; Serum; Tissue inhibitor of metalloproteinases 2; Urothelial cancer

Indexed keywords

GELATINASE A; GELATINASE INHIBITOR;

ADULT; AGED; ARTICLE; BLADDER CANCER; CANCER SURVIVAL; CONTROLLED STUDY; ENZYME IMMUNOASSAY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PREDICTION; PRIORITY JOURNAL; RECURRENT CANCER; SERUM; SUPERFICIAL CANCER; URINARY TRACT CANCER; UROTHELIUM;

EID: 0031975836     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1998.104     Document Type: Article

References (25)

1. Albini A, Melchiori A, Santi L, Liotta LA, Brown PD and Stetler-Stevenson WG (1991) Tumor cell invasion inhibited by TIMP-2. J Natl Cancer Inst 83: 775-779
2. Alvarez OA, Carmichael DF and DeClerck YA (1990) Inhibition of collagenolytic activity and metastasis of tumor cells by a recombinant human tissue inhibitor of metalloproteinase. J Natl Cancer Inst 82: 589-595
3. Cox DR (1972) Regression models and life table. J Roy Stat Soc (B) 34: 187-220
4. Davies B, Waxman J, Wasan H, Abel P, Williams G, Krausz T, Neal D, Thomas D, Hanby A and Balkwill F (1993) Levels of matrix metalloproteinases in bladder cancer correlate with tumor grade and invasion. Cancer Res 53: 5365-5369
5. DeClerck YA and Imren S (1994) Protease inhibitors: role and potential therapeutic use in human cancer. Eur J Cancer 30A: 2170-2180
6. DeClerck YA, Yean TD, Chan D, Shimada H and Langley KE (1991) Inhibition of tumor invasion of smooth muscle cell layers by recombinant human metalloproteinase inhibitor. Cancer Res 51: 2151-2157
7. DeClerck YA, Perez N, Shimada H, Boone TC, Langley KE and Taylor SM (1992) Inhibition of invasion and metastasis in cells transfected with an inhibitor of metalloproteinases. Cancer Res 52: 701-708
8. Fujimoto N, Mouri N, Iwata K, Ohuchi E, Okada Y and Hayakawa T (1993a) A one-step sandwich enzyme immunoassay for human matrix metalloproteinase 2 (72-kDa gelatinase/type IV collagenase) using monoclonal antibodies. Clin Chim Acta 221: 91-103
9. Fujimoto N, Zhang J, Iwata K, Shinya T, Okada Y and Hayakawa T (1993b) A one-step sandwich enzyme immunoassay for tissue inhibitor of metalloproteinases-2 using monoclonal antibodies. Clin Chim Acta 220: 31-45
10. Grignon DJ, Sakr W, Toth M, Ravery V, Angulo J, Shamsa F, Pontes JE, Crissman JC and Fridman R (1996) High levels of tissue inhibitor of metalloproteinase-2 (TIMP-2) expression are associated with poor outcome in invasive bladder cancer. Cancer Res 56: 1654-1659
11. Khokha R (1994) Suppression of the tumorigenic and metastatic abilities of murine B16-F10 melanoma cells in vivo by the overexpression of the tissue inhibitor of the metalloproteinases-1. J Natl Cancer Inst 86: 244-304
12. Koop S, Khokha R, Schmidt EE, MacDonald IC, Morris VL, Chambers AF and Groom AC (1994) Overexpression of metalloproteinase inhibitor in B16F10 cells does not affect extravasation but reduces tumor growth. Cancer Res 54: 4791-4797
13. Liotta LA, Tryggvason K, Garbisa S, Hart I, Foltz CM and Shafie S (1980) Metastatic potential correlates with enzymatic degradation of basement membrane collagen. Nature 284: 67-68
14. Liotta LA, Steeg PS and Stetler-Stevenson WG (1991) Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation. Cell 64: 327-336
15. Montgomery AMP, Muller BM, Reisfeld RA, Taylor SM and DeClerck YA (1994) Effect of tissue inhibitor of the matrix metalloproteinases-2 expression on the growth and spontaneous metastasis of a human melanoma cell line. Cancer Res 54: 5467-5473
16. Moses MA, Sudhalter J and Langer R (1990) Identification of an inhibitor of neovascularization from cartilage. Science 248: 1408-1410
17. Murphy AN, Unsworth EJ and Stetler-Stevenson WG (1993) Tissue inhibitor of metalloproteinases-2 inhibits bFGF-induced human microvascular endothelial cell proliferation. J Cell Physiol 157: 351-358
18. Naito K, Kanbayashi N, Nakajima S, Murai T, Arakawa K, Nishimura S and Okuyama A (1994) Inhibition of growth of human tumor cells in nude mice by a metalloproteinase inhibitor. Int J Cancer 58: 730-735
19. Nakajima M and Chop AM (1991) Tumor invasion and extracellular matrix degradative enzymes; regulation of activity by organ factors. Semin Cancer Biol 2: 115-127
20. Schnaper HW, Grant DS, Stetler-Stevenson WG, Fridman RD, Orazi G, Murphy AN, Bird RE, Hoythya M, Fuerst TR, French DL, Quigley JP and Kleinman HK (1993) Type IV collagenase(s) and TIMPs modulate endothelial cell morphogenesis in vitro. J Cell Physiol 156: 235-246
21. Schultz RM, Silberman S, Persky B, Bajkowski AS and Carmichael DF (1988) Inhibition by human recombinant tissue inhibitor of metalloproteinases of human amnion invasion and lung colonization by murine B16-F10 melanoma cells. Cancer Res 48: 5539-5545
22. Skinner DG, Daniels JR, Russell CA, Lieskovsky G, Boyd SD, Nichols P, Kern W, Sakamoto J, Krailo M and Groshen S (1991) The role of adjuvant chemotherapy following cystectomy for invasive bladder cancer: a prospective comparative trial. J Urol 145: 459-467
23. Stetler-Stevenson WG, Krutzsch HC and Liotta LA (1989) Tissue inhibitor of metalloproteinase (TIMP-2). A new member of the metalloproteinase family. J Biol Chem 264: 17374-17378
24. Takigawa M, Nishida Y, Suzuki F, Kishi J, Yamashita K and Hayakawa T (1990) Induction of angiogenesis in chick yolk-sac membrane by polyamines and its inhibition by tissue inhibitors of metalloproteinases (TIMP and TIMP-2). Biochem Biophys Res Commun 171: 1264-1271
25. Wang X, Fu X, Brown PD, Crimmin MJ and Hoffman RM (1994) Matrix metalloproteinase inhibitor BB-94 (Batimastat) inhibits human colon tumor growth and spread in a patient-like orthotopic model in nude mice. Cancer Res 54: 4726-4728