In vivo NMR spectroscopy in patients with phenylketonuria: Clinical significance of interindividual differences in brain phenylalanine concentrations

Journal of Inherited Metabolic Disease

Volumn 21, Issue 1, 1998, Pages 81-82

  Weglage, J ^a   Moller, H E ^a   Wiedermann, D ^a   Cipcic Schmidt, S ^b   Zschocke, J ^c   Ullrich, K ^d  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c PHILIPPS UNIVERSITY MARBURG   (Germany)

^d UNIVERSITY OF HAMBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PHENYLALANINE; PHENYLALANINE 4 MONOOXYGENASE;

ADULT; AMINO ACID BRAIN LEVEL; ARTICLE; BLOOD BRAIN BARRIER; CASE REPORT; DIET THERAPY; GENOTYPE; HUMAN; INTELLIGENCE QUOTIENT; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOGENESIS; PHENYLKETONURIA; WHITE MATTER;

BRAIN; HUMANS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PHENYLALANINE; PHENYLKETONURIAS;

EID: 0031975526     PISSN: 01418955     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1005327801588     Document Type: Article

References (3)

1. Moller HE, Vermathen P, Ullrich K et al (1995) In vivo NMR spectroscopy in patients with phenylketonuria : changes of cerebral phenylalanine levels under dietary treatment. Neuropediatrics 26: 199-202.
2. Novotny EJ, Avison MJ, Herschkowitz N et al (1995) In vivo measurement of phenylalanine in human brain by proton nuclear magnetic resonance spectroscopy. Pediatr Res 37: 244-249.
3. Primrose DA (1983) Phenylketonuria with normal intelligence. J Ment Defic Dis 27: 239-246.