Impact of methicillin resistance on the outcome of patients with bacteremia caused by Staphylococcus aureus

Archives of Internal Medicine

Volumn 158, Issue 2, 1998, Pages 182-189

  Harbarth, Stephan ^a   Rutschmann, Olivier ^a   Sudre, Philippe ^a   Pittet, Didier ^a  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANTIBIOTIC AGENT; BETA LACTAM ANTIBIOTIC; METICILLIN; VANCOMYCIN;

ADULT; AGED; ANTIBIOTIC RESISTANCE; ARTICLE; BACTEREMIA; BACTERIUM CULTURE; FEMALE; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MORTALITY; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION;

ADULT; AGED; AGED, 80 AND OVER; BACTEREMIA; CASE-CONTROL STUDIES; COHORT STUDIES; FEMALE; HOSPITAL MORTALITY; HOSPITALS, UNIVERSITY; HUMANS; MALE; METHICILLIN RESISTANCE; MIDDLE AGED; OUTCOME ASSESSMENT (HEALTH CARE); STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; SWITZERLAND;

EID: 0031974955     PISSN: 00039926     EISSN: None     Source Type: Journal    
DOI: 10.1001/archinte.158.2.182     Document Type: Article

References (57)

1. Stamm AM, Long MN, Belcher B. Higher overall nosocomial infection rate because of increased attack rate of methicillin-resistant Staphylococcus aureus. Am J Infect Control. 1993;21:70-74.
2. Boyce JM. Should we try vigorously to contain and control MRSA? Infect Control Hosp Epidemiol. 1991;12:46-54.
3. Myers JP, Linnemann CC Jr. Bacteremia due to methicillin-resistant Staphylococcus aureus. J Infect Dis. 1982;145:532-536.
4. Storch GA, Rajagopalan L. Methicillin-resistant Staphylococcus aureus bacteremia in children. Pediatr Infect Dis. 1986;5:59-67.
5. Cheng AF, French GL. Methicillin-resistant Staphylococcus aureus bacteraemia in Hong Kong. J Hosp Infect 1988;12:91-101.
6. Steinberg JP, Clark CC, Hackman BO. Nosocomial and community-acquired Staphylococcus aureus bacteremias from 1980 to 1993: impact of intravascular devices and methicillin resistance. Clin Infect Dis. 1996;23:255-259.
7. Crossley K, Loesch D, Landesman B, Mead K, Chern M, Strate R. An outbreak of infections caused by strains of Staphylococcus aureus resistant to methicillin and aminoglycosides, I: clinical studies. J Infect Dis. 1979;139:273-279.
8. Law MR, Gill ON. Hospital-acquired infection with methicillin-resistant and methicillin-sensitive staphylococci. Epidemiol Infect. 1988;101:623-629.
9. Pujol M, Pena C, Pallares R, Ayats J, Ariza J, Gudiol F. Risk factors for nosocomial bacteremia due to methicillin-resistant Staphylococcus aureus. Eur J Clin Microbiol Infect Dis. 1994;13:96-102.
10. Romero-Vivas J, Rubio M, Fernandez C, Picazo JJ. Mortality associated with nosocomial bacteremia due to methicillin-resistant Staphylococcus aureus. Clin Infect Dis. 1995;21:1417-1423.
11. Pujol M, Pena C, Pallares R, et al. Nosocomial Staphylococcus aureus bacteremia among nasal carriers of methicillin-resistant and methicillin-susceptibte strains. Am J Med. 1996;100:509-516.
12. Peacock JE Jr, Moorman DR, Wenzel RP, Mandell GL. Methicillin-resistant Staphylococcus aureus: microbiologic characteristics, antimicrobial susceptibilities, and assessment of virulence of an epidemic strain. J Infect Dis. 1981;144:575-582.
13. Mizobuchi S, Minami J, Jin F, Matsushita O, Okabe A. Comparison of the virulence of methicillin-resistant and methicillin-sensitive Staphylococcus aureus. Microbiol Immunol. 1994;38:599-605.
14. Lewis E, Saravolatz LD. Comparison of methicillin-resistant and methicillin-sensitive Staphylococcus aureus bacteremia. Am J Infect Control. 1985;13:109-114.
15. French GL, Cheng AF, Ling JM, Mo P, Donnan S. Hong Kong strains of methicillin-resistant and methicillin-sensitive Staphylococcus aureus have similar virulence. J Hosp Infect. 1990;15:117-125.
16. Marty L, Flahault A, Suarez B, Caillon J, Hill C, Andremont A. Resistance to methicillin and virulence of Staphylococcus aureus strains in bacteremic cancer patients. Intensive Care Med. 1993;19:285-289.
17. Hershow RC, Khayr WF, Smith NL. A comparison of clinical virulence of nosocomially acquired methicillin-resistant and methicillin-sensitive Staphylococcus aureus infections in a university hospital. Infect Control Hosp Epidemiol. 1992;13:587-593.
18. Grieble HG, Krause SL, Pappas SA, Di Costanzo MB. The prevalence of high-level methicillin resistance in multiply resistant hospital staphylococci. Medicine (Baltimore). 1981;60:62-69.
19. Ptttet D, Safran E, Harbarth S, et al. Automatic alerts for methicillin-resistant Staphylococcus aureus surveillance: role of a hospital information system. Infect Control Hosp Epidemiol. 1996;17:496-502.
20. Kloos WE, Lambe DW. Staphylococcus. In: Balows A, Hausler WJ, Herrmann KL, Isenberg HD, Shadomy HJ, eds. Manual of Clinical Microbiology. Washington, DC: American Society for Microbiology; 1991:222-237.
21. National Committee for Clinical Laboratory Standards. Performance Standards for Antimicrobial Disk Susceptibility Tests. Villanova, Pa: National Committee for Clinical Laboratory Standards; 1993:14. NCCLS document M2A5.
22. Pittet D, Wenzel RP. Nosocomial bloodstream infections: secular trends in rates, mortality, and contribution to total hospital deaths. Arch Intern Med. 1995;155:1177-1184.
23. Garner JS, Jarvis WR, Emori TG, Toran TC, Hughes JM. CDC definition for nosocomial infections. Am J Infect Control. 1988;16:128-140.
24. Brun-Buisson C, Abrouk F, Legrand P, Huet Y, Larabi S, Rapin M. Diagnosis of central venous catheter-related sepsis. Arch Intern Med. 1987;147:873-877.
25. Culver DH, Horan TO, Gaynes RP, et al. Surgical wound infection rates by wound class, operative procedure, and patient risk index: National Nosocomial Infections Surveillance System. Am J Med. 1991;91(suppl 3B):152S-157S.
26. Pittet D. Nosocomial bloodstream infections. In: Wenzel RP, ed. Prevention and Control of Nosocomial Infections. Baltimore, Md: Williams & Wilkins; 1993:512-555.
27. McCabe WR, Jackson GG. Gram-negative bacteremia, I: etiology and ecology. Arch Intern Med. 1962;110:847-855.
28. Pittet D, Thiévent B, Wenzel RP, Li N, Gurman G, Suter PM. Importance of preexisting co-morbidities for prognosis of septicemia in critically ill patients. Intensive Care Med. 1993;19:265-272.
29. Perl TM, Dvorak L, Hwang T, Wenzel RP. Long-term survival and function after suspected gram-negative sepsis. JAMA. 1995;274:338-345.
30. Bone RC, Balk RA, Cerra FB, et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis: The ACCP/SCCM Consensus Conference Committee. Chest. 1992;101:1644-1655.
31. Rangel-Frausto SM, Pittet D, Costigan M, Hwang TS, Davis CS, Wenzel RP. The natural history of the systemic inflammatory response syndrome (SIRS): a prospective study. JAMA. 1995;273:117-123.
32. Pittet D, Thiévent B, Wenzel RP, Li N, Auckenthaler R, Suter PM. Bedside prediction of mortality from bacteremic sepsis: a dynamic analysis of ICU patients. Am J Respir Crit Care Med. 1996;153:684-693.
33. Skau T, Nystrom PO, Carlsson C. Severity of illness in intra-abdominal infection: a comparison of two indexes. Arch Surg. 1985;120:152-158.
34. Wey SB, Motomi M, Pfaller MA, Woolson RF, Wenzel RP, Hospital-acquired candidemia: the attributable mortality and excess length of stay. Arch Intern Med. 1988;148:2642-2645.
35. Pittet D, Tarara D, Wenzel RP. Nosocomial bloodstream infection in critically ill patients: excess length of stay, extra costs, and attributable mortality. JAMA. 1994;271:1598-1601.
36. Kaplan EL, Meier P. Nonparametric estimation from incomplete information. J Am Stat Assoc. 1958;53:457-481.
37. Cox DR. Regression models and life-tables. J R Stat Soc. 1972;34:248-275.
38. Banerjee SN, Emori TG, Culver DH, et al. Secular trends in nosocomial primary bloodstream infections in the United States, 1980-1989: National Nosocomial Infections Surveillance System. Am J Med. 1991;91(suppl 3B):86S-89S.
39. Mylotte JM, McDermott C, Spooner JA. Prospective study of 114 consecutive episodes of Staphylococcus aureus bacteremia. Rev Infect Dis. 1987;9:891-907.
40. Kuikka A, Valtonen V. Improved outcome of Staphylococcus aureus bacteremia. Infect Dis Clin Pract. 1994;3:282-287.
41. Ronveaux O, Jans B, Mertens R. Epidemiology of methicillin-resistant Staphy- lococcus aureus (MRSA) in nosocomial infections in Belgium. Presented at the 36th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 17, 1996; New Orleans, La. Abstract.
42. Rahal JJ. Preventing second-generation complications due to Staphylococcus aureus. Arch Intern Med. 1989;149:503-504.
43. Jernigan JA, Farr BM. Short-course therapy of catheter-related Staphylococcus aureus bacteremia: a meta-analysis. Ann Intern Med. 1993;119:304-311.
44. Musher DM, Lamm N, Darouiche RO, Young EJ, Hamill RJ, Landon GC, The current spectrum of Staphylococcus aureus infection in a tertiary care hospital. Medicine (Baltimore). 1994;73:186-208.
45. Yzerman EP, Boelens HA, Tjhie JH, Kluytmans JA, Mouton JW, Verbrugh HA. Delta APACHE II for predicting course and outcome of nosocomial Staphylococcus aureus bacteremia and its relation to host defense. J Infect Dis. 1996;173:914-919.
46. Mylotte JM, Aeschlimann JR, Rotella D. Staphylococcus aureus bacteremia: factors predicting hospital mortality. Infect Control Hosp Epidemiol. 1996;17:165-168.
47. Munoz E, Goldstein UJ, Baenacquista T, Mulloy K, Wise L. Diagnosis related group 'all payor' hospital payment and medical diseases: financial risk and hospital cost in medical noncomplicating condition: stratified diagnosis related groups. Arch Intern Med. 1989;149:417-420.
48. Gross PA, DeMauro PJ, Van Antwerpen C, Wallenstein S, Chiang S. Number of comorbidities as a predictor of nosocomial infection acquisition. Infect Control Hosp Epidemiol. 1988;9:497-500.
49. Leibovici L, Pitlik SD, Konisberger H, Drucker M. Bloodstream infections in patients older than eighty years. Age Ageing. 1993;22:431-442.
50. Leibovici L, Samra Z, Konigsberger H, Drucker M, Ashkenazi S, Pitlik SD. Long-term survival following bacteremia or fungemla. JAMA. 1995;274:807-812.
51. Bates DW, Pruess KE, Lee TH. How bad are bacteremia and sepsis? outcomes in a cohort with suspected bacteremia. Arch Intern Med. 1995;155:593-598.
52. Roberts FJ, Geere IW, Goldman A. A three-year study of positive blood cultures, with emphasis on prognosis. Rev Infect Dis. 1991;13:34-46.
53. Pittet D, Li N, Woolson RF, Wenzel RP. Microbiological factors influencing the outcome of nosocomial bloodstream infections: a six-year validated, population-based model. Clin Infect Dis. 1997;24:1068-1078.
54. Chambers HP. Methicillin-resistant staphylococci. Clin Microbiol Rev. 1988;1:173-186.
55. Levine DP, Fromm BS, Reddy BR. Slow response to vancomycin or vancomycin plus rifampin in methicillin-resistant Staphylococcus aureus endocarditis. Ann Intern Med. 1991;115:674-680.
56. Moreno F, Crisp C, Jorgensen JH, Patterson JE. Methicillin-resistant Staphylococcus aureus as a community organism. Clin Infect Dis. 1995;21:1308-1312.
57. Brun-Buisson C, Doyon P, Cariet J, et al. Incidence, risk factors, and outcome of severe sepsis and septic shock in adults: a multicenter prospective study in intensive care units. JAMA. 1995;274:968-974.