Atherosclerosis: Aortic lipid changes induced by diets suggest diffuse disease with focal severity in primates that model human atheromas

Nutrition

Volumn 14, Issue 1, 1998, Pages 17-22

  Fincham, John E ^a   Benade A J S ^a   Kruger, Marita ^a   Smuts, C M ^a   Gobregts, Engela ^a   Chalton, D O ^b   Kritchevsky, David ^c  

^a SOUTH AFRICAN MEDICAL RESEARCH COUNCIL   (South Africa)

^b UNIVERSITY OF THE WESTERN CAPE   (South Africa)

^c WISTAR INSTITUTE   (United States)

Author keywords

African Green Monkey; Cholesterol; Foam cells; LDL; Linoleic acid; Low density lipoprotein; Prudent diet

Indexed keywords

CHOLESTEROL ESTER; LINOLEIC ACID; OLEIC ACID; PHOSPHATIDYLCHOLINE; POLYUNSATURATED FATTY ACID; SATURATED FATTY ACID; VEGETABLE PROTEIN;

ANIMAL MODEL; ANIMAL TISSUE; AORTA ATHEROSCLEROSIS; ARTERY INTIMA PROLIFERATION; ARTERY SURGERY; ARTICLE; ATHEROGENESIS; ATHEROGENIC DIET; ATHEROSCLEROTIC PLAQUE; CONTROLLED STUDY; DIETARY FIBER; FAT INTAKE; LIPID BLOOD LEVEL; MONKEY; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; AORTA; ARTERIOSCLEROSIS; CERCOPITHECUS AETHIOPS; CHOLESTEROL; CHOLESTEROL ESTERS; DIET, ATHEROGENIC; DISEASE MODELS, ANIMAL; FATTY ACIDS; FEMALE; LIPID METABOLISM; LIPIDS;

ANIMALIA; CERCOCEBUS; CERCOPITHECUS AETHIOPS; PRIMATES;

EID: 0031974776     PISSN: 08999007     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0899-9007(97)00388-2     Document Type: Article

References (23)

1. 1. Fincham JE, Quack G, Wülfroth P, Benadé AJS. Confirmation of efficacy of etofibrate against peripheral atherosclerosis in non-human primates which model human lesion types I-VII. Arzneimittelforschung 1996;46:519
2. 2. Stary HC. Composition and classification of human atherosclerotic lesions. Virchows Arch A Pathol Anat 1992;421:277
3. 3. Fincham JE, Faber M, Weight MJ, et al. Diets realistic for Westernized people significantly effect lipoproteins, calcium, zinc, vitamins C, E, B6 and haematology in Vervet monkeys. Atherosclerosis 1987;66: 191
4. 4. Fincham JE, Woodroof CW, van Wyk MJ, et al. Promotion and regression of atherosclerosis in Vervet monkeys by diets realistic for Westernized people, Atherosclerosis 1987;66:205
5. 5. Benadé AJS, Fincham JE, Smuts CM, et al. Plasma low density lipoprotein composition in relation to atherosclerosis in nutritionally defined Vervet monkeys. Atherosclerosis 1988;74:157
6. 6. Fincham JE, Gouws E, Woodroof WC, et al. Atherosclerosis: chronic effects of fish oil and a therapeutic diet in humans. Arterioscler Thromb 1991;11:719
7. 7. Smuts MC, Kruger M, van Jaarsveld PJ, et al. The influence of fish oil supplementation on plasma lipoproteins and arterial lipids in Vervet monkeys with established atherosclerosis. Prostaglandins Leukot Essent Fatty Acids 1992;47:129
8. 8. Kruger M, Benadé AJS, Smuts CM, et al. Comparison of the effect of the amount and degree of unsaturation of dietary fat on plasma low density lipoproteins in Vervet monkeys. Lipids 1992;27:733
9. 9. Weight MJ, Benadé AJS, Lombard CJ, et al. Low density lipoprotein kinetics in African Green Monkeys showing variable cholesterolaemic responses to diets realistic for Westernized people. Atherosclerosis 1988;73:1
10. 131I-radiolabelled plasma low density lipoprotein in hyperlipidaemic Vervet monkeys. Atherosclerosis 1989;80:159
11. 11. Adams MR, Kaplan JR, Korotnik DR, Clarkson TB. Pregnancy associated inhibition of coronary artery atherosclerosis in monkeys: evidence of a relationship with endogenous estrogen. Arterioscler Thromb 1987;7:378
12. 12. Smith EB. The influence of age and atherosclerosis on the chemistry of aortic intima. Part 1. The lipids. J Atheroscler Res 1964;5:261
13. 13. Bowyer DE. Recovery of lipids from aortas stained with Sudan IV [letter]. Atherosclerosis 1977;26:387
14. 14. Kritchevsky D, Davidson LM, Hong KK, Winter PAD. Lipid levels in serum, liver and aorta of the Vervet monkey. J Med Primatol 1973; 2:242
15. 15. Kim HK, Davidson LM, Kritchevsky D. Quantitative recovery of lipids from aortas stained with Sudan IV. Atherosclerosis 1976;23:559
16. 16. Lundberg B. Chemical composition and physical state of lipid deposits in atherosclerosis. Atherosclerosis 1985;56:93
17. 17. Folch J, Lees M, Sloan-Stanley GH. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 1957;226:497
18. 18. Itaya K, Ui M. A new micromethod for the colorimetric determination of inorganic phosphate. Clin Chim Acta 1966;14:361
19. 19. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 1993;362:801
20. 20. Kotze HF, van Wyk V, Fincham JE, et al. Changes in platelet function in atherosclerotic nonhuman primates after long-term dietary supplementation with fish oil and sunflower oil. Cardiovasc J S Afr 1995; 6:211
21. 21. Newman HAI, Silversmit DB. Accumulation of lipid and non-lipid in rabbit atheroma. J Atheroscler Res 1964;4:261
22. 22. Kritchevsky D, Tepper SA. Experimental atherosclerosis in rabbits fed cholesterol-free diets: influence of chow components. J Atheroscler Res 1968;8:357
23. 23. Wolfe MS, Parks JS, Morgan TM, Rudel LL. Age and dietary polyunsaturated fat alter high density lipoprotein subfraction cholesterol concentrations in a paediatric population of African Green Monkeys. Arterioscler Thromb 1991;11:617