Analysis of the mechanisms of action of the Saccharomyces cerevisiae dominant lethal cdc42(G12V) and dominant negative cdc42(D118A) mutations

Journal of Biological Chemistry

Volumn 273, Issue 2, 1998, Pages 849-858

  Davis, Cynthia R ^a,b   Richman, Tamara J ^a   Deliduka, Steven B ^a   Blaisdell, Jeffrey O ^a   Collins, Cheryl C ^a   Johnson, Douglas I ^a  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^b EASTERN NAZARENE COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATASE;

ARTICLE; CELL POLARITY; ENZYME LOCALIZATION; GENE ISOLATION; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; CDC42 GTP-BINDING PROTEIN, SACCHAROMYCES CEREVISIAE; CELL CYCLE PROTEINS; GENES, DOMINANT; GENES, LETHAL; GTP-BINDING PROTEINS; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; PHENOTYPE; SACCHAROMYCES CEREVISIAE; SEQUENCE DELETION; SEQUENCE HOMOLOGY, AMINO ACID; TEMPERATURE;

EID: 0031974630     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.2.849     Document Type: Article

References (72)

1. Drubin, D. G., and Nelson, W. J. (1996) Cell 84, 335-344
2. Chant, J. (1994) Trends Genet. 10, 328-333
3. Madden, K., Costigan, C., and Snyder, M. (1992) Trends Cell Biol. 2, 22-29
4. Herskowitz, I., Park, H.-O., Sanders, S., Valtz, N., and Peter, M. (1995) Cold Spring Harbor. Symp. Quant. Biol. 60, 717-727
5. Pringle, J. R., Bi, E., Harkins, H. A., Zahner, J. E., De Virgilio, C., Chant, J., Corrado, K., and Fares, H. (1995) Cold Spring Harbor Symp. Quant. Biol. 60, 729-744
6. Chant, J., and Pringle, J. R. (1991) Curr. Opin. Genet. Dev. 1, 342-350
7. Drubin, D. G. (1991) Cell 65, 1093-1096
8. Bourne, H. R., Sanders, D. A., and McCormick, F. (1991.) Nature 349, 117-127
9. Boguski, M. S., and McCormick, F. (1993) Nature 366, 643-654
10. Bender, A., and Pringle, J. R. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 9976-9980
11. Chant, J., and Herskowitz, I. (1991) Cell 65, 1203-1212
12. Ruggieri, R., Bender, A., Matsui, Y., Powers, S., Takai, Y., Pringle, J. R., and Matsumoto, K. (1992) Mol. Cell. Biol 12, 758-766
13. Johnson, D. I., and Pringle, J. R. (1990) J. Cell Biol. 111, 143-152
14. Johnson, D. I. (1993) in The ras Superfamily of GTPases (Lacal, J. C., and McCormick, F., eds) pp. 297-312, CRC Press, Inc., Boca Raton, FL
15. Miller, P. J., and Johnson, D. I. (1997) Yeast 13, 561-572
16. Ziman, M., O'Brien, J. M., Ouellette, L. A., Church, W. R., and Johnson, D. I. (1991) Mol. Cell. Biol 11, 3537-3544
17. Yamochi, I., Tanaka, H., Nonaka, H., Maeda, A., Musha, T., and Takai, Y. (1994) J. Cell Biol. 125, 1077-1093
18. Matsui, Y., and Toh-e, A. (1992) Mol. Cell. Biol 12, 5690-5699
19. Imai, J., Toh-e, A., and Matsui, Y. (1996) Genetics 142, 359-369
20. Nonaka, H., Tanaka, K., Hirano, H., Fujiwara, T., Kohno, H., Umikawa, M., Mino, A., and Takai, Y. (1995) EMBO J. 14, 5931-5938
21. Qadota, H., Python, C. P., Inoue, S. B., Arisawa, M., Anraku, Y., Zheng, Y., Watanabe, T., Levin, D. E., and Ohya, Y. (1996) Science 272, 279-281
22. Mazur, P., and Baginsky, W. (1996) J. Biol. Chem. 271, 14604-14609
23. Inoue, S. B., Qadota, H., Arisawa, M., Watanabe, T., and Ohya, Y. (1996) Cell Struct. Funct. 21, 395-402
24. Miller, P., and Johnson, D. I. (1994) Mol. Cell. Biol 14, 1075-1083
25. Ottilie, S., Miller, P. J., Johnson, D. I., Creasy, C. L., Sells, M. A., Bagrodia, S., Forsburg, S. L., and Chernoff, J. (1995) EMBO J. 14, 5908-5919
26. Chen, W., Lim, H. H., and Lim, L. (1993) J. Biol. Chem. 268, 13280-13285
27. Luo, L., Liao, Y. J., Jan, L. Y., and Jan, Y. N. (1994) Genes Dev. 8, 1787-1802
28. Shinjo, K., Koland, J. G., Hart, M. J., Narasimhan, V., Johnson, D. I., Evans, T., and Cerione, R. A. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 9853-9857
29. Munemitsu, S., Innis, M. A., Clark, R., McCormick, F., Ullrich, A., and Polakis, P. (1990) Mol. Cell. Biol 10, 5977-5982
30. Cvrckova, F., De Virgilio, C., Manser, E., Pringle, J. R., and Nasmyth, K. (1995) Genes Dev. 9, 1817-1830
31. Manser, E., Leung, T., Salihuddin, H., Zhao, Z., and Lim, L. (1994) Nature 367, 40-46
32. Martin, H., Mendoza, A., Rodriguez-Pachon, J. M., Molina, M., and Nombela, C. (1997) Mol. Microbiol. 23, 431-444
33. Leberer, E., Wu, C., Leeuw, T., Fourest-Lieuvin, A., Segall, J. E., and Thomas, D. Y. (1997) EMBO J. 16, 83-97
34. Peter, M., Neiman, A. M., Park, H.-O., Lohuizen, M. V., and Herskowitz, I. (1996) EMBO J. 15, 7046-7059
35. Ziman, M., and Johnson, D. I. (1994) Yeast 10, 463-474
36. Cerione, R. A., and Zheng, Y. (1996) Curr. Opin. Cell Biol. 8, 216-222
37. Zheng, Y., Cerione, R., and Bender, A. (1994) J. Biol. Chem. 269, 2369-2372
38. Ziman, M., Preuss, D., Mulholland, J., O'Brien, J. M., Botstein, D., and Johnson, D. I. (1993) Mol. Biol. Cell 4, 1307-1316
39. Finegold, A. A., Johnson, D. I., Farnsworth, C. C., Gelb, M. H., Judd, S. R., Glomset, J. A., and Tamanoi, F. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 4448-4452
40. Hancock, J. F., Cadwallader, K., Paterson, H., and Marshall, C. J. (1991) EMBO J. 10, 4033-4039
41. Hancock, J. F., Paterson, H., and Marshall, C. J. (1990) Cell 63, 133-139
42. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd Ed., Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
43. Sherman, F., Fink, G. R., and Hicks, J. B. (1986) Methods in Yeast Genetics: Laboratory Manual, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
44. Feilotter, H. E., Hannon, G. J., Ruddell, C. J., and Beach, D. (1994) Nucleic Acids Res. 22, 1502-1503
45. Birnboim, H. C., and Doly, J. (1979) Nucleic Acids Res. 7, 1513-1523
46. Sanger, F., Nicklen, S., and Coulson, A. R. (1977)Proc. Natl. Acad. Sci. U. S. A. 74, 5463-5467
47. Johnston, M., and Davis, R. W. (1984) Mol. Cell. Biol. 4, 1440-1448
48. Sikorski, R. S., and Hieter, P. (1989) Genetics 122, 19-27
49. Christianson, T. W., Sikorski, R. S., Dante, M., Shero, J. H., and Hieter, P. (1992) Gene (Amst.) 110, 119-122
50. Jones, J. S., and Prakash, L. (1990) Yeast 6, 363-366
51. Kang, Y. S., Kane, J., Kurjan, J., Stadel, J. M., and Tipper, D. J. (1990) Mol. Cell. Biol 10, 2582-2590
52. Durfee, T., Becherer, K., Chen, P.-L., Yeh, S.-H., Yang, Y., Kilburn, A. E., Lee, W.-H., and Elledge, S. J. (1993) Genes Dev. 7, 555-569
53. Chien, C.-T., Bartel, P. L., Sternglanz, R., and Fields, S. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 9578-9582
54. Rokeach, L. A., Haselby, J. A., and Hoch, S. O. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 4832-4836
55. Zhou, Y., Zhang, X., and Ebright, R. H. (1991) Nucleic Acids Res. 19, 6052
56. Reynolds, A., and Lundblad, V. (1989) in Current Protocols in Molecular Biology (Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A., and Struhl, K., eds) Vol. 2, pp. 13.6.2-13.6.4, John Wiley & Sons, Inc., New York
57. Laemmli, U. K. (1970) Nature 227, 680-685
58. Li, R., and Zheng, Y. (1997) J. Biol. Chem. 272, 4671-4679
59. Eaton, S., Wepf, R., and Simons, K. (1996) J Cell Biol. 135, 1277-1289
60. Marcus, S., Polverino, A., Chang, E., Robbins, D., Cobb, M. H., and Wigler, M. H. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 6180-6184
61. Simon, M. N., De Virgilio, C., Souza, B., Pringle, J. R., Abo, A., and Reed, S. I. (1995) Nature 376, 702-705
62. Han, M., and Sternberg, P. W. (1991) Genes Dev. 5, 2188-2198
63. Marshall, M. S. (1993) Trends Biochem. Sci. 18, 250-254
64. Polakis, P., and McCormick, F. (1993) J. Biol. Chem. 268, 9157-9160
65. Zheng, Y., Glaven, J. A., Wu, W. J., and Cerione, R. A. (1996) J. Biol. Chem. 271, 23815-23819
66. Sloat, B. F., Adams, A., and Pringle, J. R. (1981) J. Cell Biol. 89, 395-405
67. Madaule, P., Axel, R., and Myers, A. M. (1987) Proc. Natl. Acad. Sci. U. S. A. 84, 779-783
68. Qadota, H., Anraku, Y., Botstein, D., and Ohya, Y. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 9317-9321
69. Watanabe, M., Chen, C.-Y., and Levin, D. E. (1994) J. Biol. Chem. 269, 16829-16836
70. Parrini, M. C., Bernardi, A., and Parmeggiani, A. (1996) EMBO J. 15, 1107-1111
71. Wood, D. R., Poullet, P., Wilson, B. A., Khalil, M., Tanaka, K., Cannon, J. F., and Tamanoi, F. (1994) J. Biol. Chem. 269, 5322-5327
72. Milburn, M. V., Tong, L., DeVos, A. M., Brunger, A., Yamaizumi, Z., Nishimura, S., and Kim, S. H. (1990) Science 247, 939-945