The role of ligand flexibility in predicting biological activity: Structure-activity relationships for aryl hydrocarbon, estrogen, and androgen receptor binding affinity

Environmental Toxicology and Chemistry

Volumn 17, Issue 1, 1998, Pages 15-25

  Bradbury, Steven P ^a   Mekenyan, Ovanes G ^b   Ankley, Gerald T ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b BURGAS FREE UNIVERSITY   (Bulgaria)

Author keywords

Androgen receptor; Aryl hydrocarbon receptor; Estrogen receptor; Receptor binding affinity; Structure activity relationships

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; AROMATIC HYDROCARBON; AROMATIC HYDROCARBON RECEPTOR; ESTROGEN; ESTROGEN RECEPTOR; STEROID HORMONE; XENOBIOTIC AGENT;

BINDING AFFINITY; DNA RESPONSIVE ELEMENT; DRUG ACTIVITY; ECOTOXICOLOGY; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DNA INTERACTION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RECEPTOR BINDING; REVIEW; RISK ASSESSMENT; STRUCTURE ACTIVITY RELATION; TRANSACTIVATION;

EID: 0031974310     PISSN: 07307268     EISSN: None     Source Type: Journal    
DOI: 10.1897/1551-5028(1998)017<0015:TROLFI>2.3.CO;2     Document Type: Review

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