Dipeptidase inhibitor and epithelial removal potentiate leukotriene D4- induced human tracheal smooth muscle contraction

Respiration Physiology

Volumn 111, Issue 1, 1998, Pages 101-109

  Yamaya, Mutsuo ^a   Sekizawa, Kiyohisa ^a   Terajima, Masanori ^a   Okinaga, Shoji ^a   Ohrui, Takashi ^a   Sasaki, Hidetada ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Airways, smooth muscle, contraction; Epithelium, bronchial, smooth muscle contraction; Mammals, humans; Mediators, leukotriene D4; Pharmacological agents, dipeptidase inhibitor; Smooth muscle, contraction, epithelium

Indexed keywords

CYSTEINE; ENZYME INHIBITOR; LEUKOTRIENE D4;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; EPITHELIUM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; SMOOTH MUSCLE CONTRACTION; TRACHEA MUCOSA; TRACHEA MUSCLE;

ACETYLCHOLINE; ADULT; AGED; AGED, 80 AND OVER; CELLS, CULTURED; CILASTATIN; CYSTEINE; DIPEPTIDASES; DRUG SYNERGISM; EPITHELIUM; HUMANS; LEUKOTRIENE D4; MIDDLE AGED; MUSCLE CONTRACTION; MUSCLE, SMOOTH; PROTEASE INHIBITORS; TRACHEA;

EID: 0031974182     PISSN: 00345687     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0034-5687(97)00099-6     Document Type: Article

References (35)

1. Adachi H., Kubota I., Okamura N., Iwata H., Tsujimoto M., Nakazato H., Nishihara T., Noguchi T. Purification and characterization of human microsomal dipeptidase. J. Biochem. 105:1989;957-961.
2. Adachi H., Tawaragi Y., Inuzuka C., Kubota I., Tsujimoto M., Nishihara T., Nakazato H. Primary structure of human microsomal dipeptidase deduced from molecular cloning. J. Biol. Chem. 265:1990;3992-3995.
3. Adachi H., Katayama T., Nakazato H., Tsujimoto M. Importance of Glu-125 in the catalytic activity of human renal dipeptidase. Biochim. Biophys. Acta. 1163:1993;42-48.
4. Aizawa T., Sekizawa K., Aikawa T., Maruyama N., Itabashi S., Tamura G., Sasaki H., Takishima T. Eosinophil supernatant causes hyperresponsiveness of airway smooth muscle in guinea pig trachea. Am. Rev. Respir. Dis. 142:1990;133-137.
5. 4, and histamine in normal human subjects. Thorax. 39:1984;500-504.
6. Bernström K., Hammarström S. Metabolism of leukotriene D by porcine kidney. J. Biol. Chem. 256:1981;9579-9582.
7. Buckner C.K., Fedyna J.S., Robertson J.L., Will J.A., England D.M., Krell R.D., Saban R. An examination of the influence of the epithelium on contractile responses to peptidoleukotrienes and blockade by ICI 204 219 in isolated guinea pig trachea and human intralobar airways. J. Pharmacol. Exp. Ther. 252:1990;77-85.
8. Campbell B.J., Forrester L.J., Zahler W.L., Burks M. β-lactamase activity of purified and partially characterized human renal dipeptidase. J. Biol. Chem. 259:1984;14586-14590.
9. Campbell B.J., Shih Y.D., Forrester L.J., Zahler W.L. Specificity and inhibition studies of human renal dipeptidase. Biochim. Biophys. Acta. 956:1988;110-118.
10. 4 by lung dipeptidase. Biochim. Biophys. Acta. 1042:1990;107-112.
11. Creticos P.S., Peters S.P., Adkinson N.F., Naclerio R.M., Hayes E.C., Norman P.S., Lichtenstein L.M. Peptide leukotriene release after antigen challenge in patients sensitive to ragweed. New Engl. J. Med. 310:1984;1626-1630.
12. Dahlén S.-E., Hedqvist P., Hammarström S., Samuelsson B. Leukotrienes are potent constrictors of human bronchi. Nature. 288:1980;484-486.
13. 4. Proc. Natl. Acad. Sci. USA. 80:1983;1712-1716.
14. Drazen J.M., Austen K.F. Leukotrienes and airway responses. Am. Rev. Respir. Dis. 136:1987;985-998.
15. Funayama T., Sekizawa K., Yamaya M., Yamauchi K., Ohno I., Ohrui T., Terajima M., Okinaga S., Sasaki H. Role of leukotriene-degrading enzymes in pulmonary response to antigen infusion in sensitized guinea pigs in vivo. Am. J. Respir. Cell Mol. Biol. 15:1996;260-267.
16. Griffin M., Weiss J.W., Leitch A.G., McFadden E.R., Corey E.J., Austen K.F., Drazen J.M. Effects of leukotriene D on the airways in asthma. New Engl. J. Med. 308:1983;436-439.
17. Hayes E.C., Lombardo D.L., Girard Y., Maycock A.L., Rokach J., Rosenthal A.S., Young R.N., Egan R.W., Zweerink H.J. Measuring leukotrienes of slow reacting substance of anaphylaxis: Development of a specific radioimmunoassay. J. Immunol. 131:1983;429-433.
18. Kozak E.M., Tate S.S. Glutathione-degrading enzymes of microvillus membranes. J. Biol. Chem. 257:1982;6322-6327.
19. Laitinen L.A., Heino M., Laitinen A., Kava T., Haahtela T. Damage of the airway epithelium and bronchial reactivity in patients with asthma. Am. Rev. Respir. Dis. 131:1985;599-606.
20. Lewis R.A., Austen K.F., Drazen J.M., Clark D.A., Marfat A., Corey E.J. Slow reacting substances of anaphylaxis: Identification of leukotrienes C-1 and D from human and rat sources. Proc. Natl. Acad. Sci. USA. 77:1980;3710-3714.
21. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:1951;265-275.
22. Mathews W.R., Rokach J., Murphy R.C. Analysis of leukotrienes by high-pressure liquid chromatography. Anal. Biochem. 118:1981;96-101.
23. McLean I.W., Nakane P.K. Periodate-lysineparaformaldehyde fixative - A new fixative for immunoelectron microscopy. J. Histochem. Cytochem. 22:1974;1077-1083.
24. Metz S.A., Hall M.E., Harper T.W., Murphy R.C. Rapid extraction of leukotrienes from biologic fluids and quantitation by high-performance liquid chromatography. J. Chromatogr. 233:1982;193-201.
25. Ohrui T., Yamauchi K., Sekizawa K., Ohkawara Y., Maeyama K., Sasaki M., Takemura M., Wada H., Watanabe T., Sasaki H., Takishima T. Histamine N-methyltransferase controls the contractile response of guinea pig trachea to histamine. J. Pharmacol. Exp. Ther. 261:1992;1268-1272.
26. Örning L., Hammarström S. Inhibition of leukotriene C and leukotriene D biosynthesis. J. Biol. Chem. 255:1980;8023-8026.
27. Schönfeld W., Köller M., Knöller J., König W., Muller W., Van Der Hardt H. Leukotrienes and their metabolism in plasma and bronchial fluids. J. Allergy Clin. Immunol. 75:1985;126.
28. Sekizawa K., Tamaoki J., Graf P.D., Basbaum C.B., Borson D.B., Nadel J.A. Enkephalinase inhibitor potentiates mammalian tachykinin-induced contraction in ferret trachea. J. Pharmacol. Exp. Ther. 243:1987;1211-1217.
29. Snyder D.W., Aharony D., Dobson P., Tsai B.S., Krell R.D. Pharmacological and biochemical evidence for metabolism of peptide leukotrienes by guinea-pig airway smooth muscle in vitro. J. Pharmacol. Exp. Ther. 231:1984;224-229.
30. Sok D.-E., Pai J.-K., Atrache V., Sih C.J. Characterization of slow reacting substances (SRSs) of rat basophilic leukemia (RBL-1) cells: Effect of cysteine on SRS profile. Proc. Natl. Acad. Sci. USA. 77:1980;6481-6485.
31. Sok D.E., Pai J.-K., Atrache V., Kang Y.C., Sih C.J. Enzymatic inactivation of SRS-cys-gly (leukotriene D). Biochem. Biophys. Res. Commun. 101:1981;222-229.
32. Undem B.J., Raible D.G., Adkinson N.F., Adams G.K. Effect of removal of epithelium on antigen-induced smooth muscle contraction and mediator release from guinea pig isolated trachea. J. Pharmacol. Exp. Ther. 244:1988;659-665.
33. Weiss J.W., Drazen J.M., McFadden E.R., Weller P., Corey E.J., Lewis R.A., Austen K.F. Airway constriction in normal humans produced by inhalation of leukotriene D. Potency, time course and effect of aspirin therapy. J. Am. Med. Assoc. 249:1983;2814-2817.
34. Yamaya M., Finkbeiner W.E., Chun S.Y., Widdicombe J.H. Differentiated structure and function of cultures from human tracheal epithelium. Am. J. Physiol. 262:1992;L713-L724.
35. Yamaya M., Sekizawa K., Masuda T., Morikawa M., Sawai T., Sasaki H. Oxidants affect permeability and repair of the cultured human tracheal epithelium. Am. J. Physiol. 268:1995;L284-L293.