The remarkable influence of steroid A/B-ring junction on the Wittig olefination reaction of the 11-oxo group: Towards the synthesis of 5α- and 5β-oriented Δ3-isomers of desogestrel

Steroids

Volumn 63, Issue 1, 1998, Pages 21-27

  Ring, Sven ^a   Weber, Gisela ^a   Hillisch, Alexander ^b   Schwarz, Sigfrid ^a  

^a BAYER PHARMA AG   (Germany)

^b FRITZ LIPMANN INSTITUTE   (Germany)

Author keywords

Computational studies; Deoxygenation; Desogestrel isomers; Wittig olefination

Indexed keywords

DESOGESTREL; ORAL CONTRACEPTIVE AGENT; STEROID;

ARTICLE; COMPUTER MODEL; CRYSTAL STRUCTURE; DRUG STRUCTURE; DRUG SYNTHESIS; HORMONAL CONTRACEPTION; ISOMERISM; ORAL CONTRACEPTION;

ALKENES; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; DESOGESTREL; MATHEMATICAL COMPUTING; STEREOISOMERISM;

EID: 0031973630     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-128X(97)00105-0     Document Type: Article

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