Benefit of heparin in central venous and pulmonary artery catheters: A meta-analysis of randomized controlled trials

Chest

Volumn 113, Issue 1, 1998, Pages 165-171

  Randolph, Adrienne G ^a   Cook, Deborah J ^b   Gonzalez, Calle A ^c   Andrew, Maureen ^b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b MCMASTER UNIVERSITY   (Canada)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Central venous catheter; Heparin; Infection; Thrombosis; Thrombus

Indexed keywords

HEPARIN;

ARTICLE; BACTEREMIA; BACTERIAL COLONIZATION; CATHETER INFECTION; CENTRAL VENOUS CATHETER; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; HEPARINIZATION; HUMAN; INFECTION PREVENTION; INFECTIOUS COMPLICATION; MEDICAL INFORMATION; META ANALYSIS; PRIORITY JOURNAL; PULMONARY ARTERY; RANDOMIZED CONTROLLED TRIAL; THROMBOSIS PREVENTION; VEIN THROMBOSIS;

EID: 0031973452     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.113.1.165     Document Type: Article

References (32)

1. Hoar PF, Wilson RM, Mangano DT, et al. Heparin bonding reduces thrombogenicity of pulmonary-artery catheters. N Engl J Med 1981; 305:993-95
2. Chastre J, Cornud F, Bouchama A, et al. Thrombosis as a complication of pulmonary-artery catheterization within the internal jugular vein. N Engl J Med 1982; 306:278-81
3. Valerio D, Hussey JK, Smith FW. Central venous thrombosis associated with intravenous feeding: a prospective study. JPEN J Parenter Enterai Nutr 1981; 5:240-42
4. Andrew M, Marzinotto V, Pencharz P, et al. A cross-sectional study of catheter-related thrombosis in children receiving total parenteral nutrition at home. J Pediatr 1995; 126:358-63
5. Krafte-Jacobs B, Sivit CJ, Mejia R, et al. Catheter-related thrombosis in critically ill children: comparison of catheters with and without heparin bonding. J Pediatr 1995; 126:50-54
6. Talbott GA, Winters WD, Bratton SL, et al. A prospective study of femoral catheter-related thrombosis in children. Arch Pediatr Adolesc Med 1995; 149:288-91
7. Raad ML II, Khalil S-AM, Costerton JW, et al. The relationship between the thrombotic and infectious complications of central venous catheters. JAMA 1994; 271:1014-16
8. Warkentin TE, Levine MN, Hirsh J, et al. Heparin-induced thrombocytopenia in patients treated with low-molecular weight heparin or unfractionated heparin. N Engl J Med 1995; 332:1330-35
9. American Society of Hospital Pharmacists. ASHP therapeutic position statement on the institutional use of 0.9% sodium chloride injection to maintain the patency of peripheral indwelling intermittent infusion devices. Am J Hosp Pharm 1994; 51:1572-74
10. Maki DG, Weise CE, Sarafin HW. A semiquantitative culture method for identifying intravenous-catheter-related infection. N Engl J Med 1977; 296:1305-09
11. 10aDerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986; 7:177-88
12. Fleiss JL. The statistical basis of meta-analysis. Stat Methods Med Res 1993; 2:121-45
13. Brismar B, Hardstedt C, Jacobson S, et al. Reduction of catheter-associated thrombosis in parenteral nutrition by intravenous heparin therapy. Arch Surg 1982; 117:1196-99
14. Monreal M, Alastrue A, Rull M, et al. Upper extremity deep venous thrombosis in cancer patients with venous access devices - prophylaxis with a low molecular weight heparin (Fragmin). Thromb Haemost 1996; 75:251-53
15. Smith S, Dawson S, Henuessey R, et al. Maintenance of patency of central venous catheters: is heparin necessary? Am J Pediatr Hematol Oncol 1991; 13:141-43
16. Macoviak JA, Melnik G, McLean G, et al. The effect of low-dose heparin on the prevention of venous thrombosis in patients receiving short-term parenteral nutrition. Curr Surg 1984; 41:98-100
17. Bailey MJ. Reduction of catheter-associated sepsis in parenteral nutrition using low-dose intravenous heparin. BMJ 1979; 1:1671-73
18. Appelgren P, Ransjo U, Bindslev L, et al. Surface heparinization of central venous catheters reduces microbial colonization in vitro and in vivo: results from a prospective, randomized trial. Crit Care Med 1996; 24:1482-89
19. Fabri PJ, Mirtallo JM, Ebbert ML, et al. Clinical effect of nonthrombotic total parenteral nutrition catheters. JPEN J Parenter Enteral Nutr 1984; 8:705-07
20. Fabri PJ, Mirtallo JM, Ruberg RL, et al. Incidence and prevention of thrombosis of the subelavian vein during total parenteral nutrition. Surg Gynecol Obstet 1982; 155:238-40
21. Fassolt A, Brandli F, Braun U. Antothrombotika zur prophylaxe der begleitthrombosen bei infraklavikularen vena-cavakathetern. Infusionsther Transfusionmed 1979; 6:50-54
22. Efsing HO, Lindblad B, Mark J, et al. Thromboembolic complications from central venous catheters: a comparison of three catheter materials. World J Surg 1983; 7:419-23
23. Ruggiero RP, Aisenstein TJ. Central catheter fibrin sleeve - heparin effect. JPEN J Parenter Enteral Nutr 1983; 7:270-73
24. Huraib S, Askar A, Abu-Aisha H, et al. Prevalence of infection from subclavian dialysis catheters with two different postinsertion catheter cares: a randomized comparative study. Angiology 1994; 45:1047-51
25. Mangano DT. Heparin bonding and long-term protection against thrombogenesis. N Engl J Med 1982; 307:894-95
26. Bennegard K, Curelaru I, Gustavsson B, et al. Material thrombogenicity in central venous catheterization: I. A comparison between uncoated and heparin-coated, long antebrachial, polyethylene catheters. Acta Anaesthesiol Scand 1982; 26:112-20
27. Mollenholt P, Eriksson I, Andersson T. Thrombogenicity of pulmonary-artery catheters. Intensive Care Med 1987; 13: 57-59
28. Kudsk KA, Powell C, Mirtallo JM, et al. Heparin does not reduce catheter sepsis during total parenteral nutrition. JPEN J Parenter Enteral Nutr 1985; 9:348-49
29. Mermel LA, Stolz SM, Maki DG. Surface antimicrobial activity of heparin-bonded and antiseptic-impregnated vascular catheters. J Infect Dis 1993; 167:920-24
30. Arnander C, Bagger-Sjoback D, Frebelius S, et al. Long-term stability in vivo of a heparinized surface. Biomaterials 1987; 8:496-99
31. Bern MM, Lokich JJ, Wallach SR, et al. Very low doses of warfarin can prevent thrombosis in central venous catheters: a randomized prospective trial. Ann Intern Med 1990; 112: 423-28
32. Geerts WH, Jay RM, Code KI, et al. A comparison of low-dose heparin with low-molecular weight heparin as prophylaxis against venous thromboembolism after major trauma. N Engl J Med 1996; 335:701-07