5 The Use of Embryonic Stem Cells for the Genetic Manipulation of the Mouse

Current Topics in Developmental Biology

Volumn 36, Issue C, 1997, Pages 99-108

  Torres, Miguel ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; CYTOLOGY; EMBRYO; GENE TARGETING; GENE VECTOR; MOUSE; REVIEW; STEM CELL;

ANIMALS; EMBRYO; GENE TARGETING; GENETIC VECTORS; MICE; STEM CELLS;

EID: 0031973366     PISSN: 00702153     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0070-2153(08)60497-4     Document Type: Article

References (17)

1. Bradley, A., Production and analysis of chimeric mice. Robertson, E.J., (eds.) “Teratocarcinomas and Embryonic Stem Cells: A Practical Approach”, 1987, IRL Press, Oxford, Washington, DC, 113-151.
2. Capecchi, M.R., The new mouse genetics: Altering the genome by gene targeting. Trends Genet. 5 (1989), 70-76.
3. Deng, C., Capecchi, M.R., Reexamination of gene targeting frequency as a function of the extent of homology between the targeting vector and the target locus. Mol. Cell Biol. 12 (1992), 3365-3371.
4. Friedrich, G., Soriano, P., Promoter traps in embryonic stem cells: A genetic screen to identify and mutate developmental genes in mice. Genes Dev. 5 (1991), 1513-1523.
5. Gossler, A., Doetschman, T., Korn, R., Serfling, E., Kemler, R., Transgenesis by means of blastocyst-derived embryonic stem cell lines. Proc. Natl. Acad. Sci. U.S.A. 83 (1986), 9065-9069.
6. Gossler, A., Joyner, A.L., Rossant, J., Skarnes, W.C., Mouse embryonic stem cells and reporter constructs to detect developmentally regulated genes. Science 244 (1989), 463-465.
7. Hogan, B., Beddington, R., Constantini, F., Lacy, E., “Manipulating the Mouse Embryo”, 2nd ed., 1994, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
8. Mansour, S.L., Thomas, K.R., Capecchi, M.R., Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: A general strategy for targeting mutations to non-selectable genes. Nature 336 (1988), 348-352.
9. Mansouri, A., Stoykova, A., Torres, M., Gruss, P., Dysgenesis of Cephalic neural crest derivatives in Pax-7-l-mutant mice. Development 122 (1996), 831-838.
10. Nagy, A., Rossant, J., Nagy, R., Abramow-Newerly, W., Roder, J.C., Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc. Natl. Acad. Sci. U.S.A. 90 (1993), 8424-8428.
11. Riele, H.R., Maandag, E.B., Berns, A., Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs. Proc. Natl. Acad. Sci. U.S.A. 89 (1992), 5128-5132.
12. Robertson, E.J., Pluripotent stem cell lines as a route into the mouse germline. Trends Genet. 2 (1986), 9-13.
13. Robertson, E.J., Embryo-derived stem cell lines. Robertson, E.J., (eds.) “Teratocarcinomas and Embryonic Stem Cells: A Practical Approach”, 1987, IRL Press, Oxford, Washington, DC, 71-112.
14. Skames, W.C., Auerbach, B.A., Joyner, A.L., A gene trap approach in mouse embryonic stem cells: The LacZ reporter is activated by splicing reflects endogenous gene expression, and is mutagenic in mice. Genes Dev. 6 (1992), 903-918.
15. Subramanian, V., Meyer, B.I., Gruss, P., Disruption of the murine homeobox gene Cdxl affects axial skeletal identities by altering the mesodermal expression domains of Hox genes. Cell 83 (1995), 641-653.
16. Torres, M., Gémez-Pardo, E.G., Dressler, G.R., Gruss, P., Pax-2 controls multiple steps of urogenital development. Development 121 (1995), 4057-4065.
17. Yamada, G., Mansouri, M., Torres, M., Blum, M., Stuart, E.T., Schultz, M., de Robertis, E., Gruss, P., Targeted mutation of the mouse Goosecoid gene leads to neonatal death and craniofacial defects in mice. Development 121 (1995), 2917-2922.