Defective intracellular transport of tissue-nonspecic alkaline phosphatase with an Ala162→Thr mutation associated with lethal hypophosphatasia

Journal of Biochemistry

Volumn 123, Issue 5, 1998, Pages 968-977

  Shibata, Hisanobu ^a   Fukushi, Mariko ^a   Igarashi, Atsuko ^a   Misumi, Yoshio ^b   Ikehara, Yukio ^b   Ohashi, Yasushi ^a   Oda, Kimimitsu ^a  

^a NIIGATA UNIVERSITY   (Japan)

^b FUKUOKA UNIVERSITY   (Japan)

Author keywords

Aggregation; Defective intracellular transport; Glycosylphosphatidylinositol; Hypophosphatasia; Tissue nonspecific alkaline phosphatase

Indexed keywords

ALKALINE PHOSPHATASE; CELL SURFACE PROTEIN; ETHANOLAMINE; GLUCOSAMINIDASE; MUTANT PROTEIN; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE PHOSPHODIESTERASE; TRITIUM;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL STRAIN COS1; CELL SURFACE; CONTROLLED STUDY; DISULFIDE BOND; DNA TRANSFECTION; ENZYME ACTIVITY; ENZYME SYNTHESIS; HYPOPHOSPHATASIA; IMMUNOFLUORESCENCE TEST; INTRACELLULAR TRANSPORT; ISOTOPE LABELING; MOLECULAR WEIGHT; NONHUMAN; PROTEIN PROCESSING; PROTEIN TRANSPORT; STRUCTURE ACTIVITY RELATION;

EID: 0031971180     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a022032     Document Type: Article

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