On the role of cholecystokinin in the mediation of spinal reflex excitability in intact and axotomized rats

Neuropeptides

Volumn 32, Issue 1, 1998, Pages 73-78

  Lucas, G A ^a   Xu, X J ^a   Wiesenfeld Hallin, Z ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

4 [[2 [2 [[(2 ADAMANTYLOXY)CARBONYL]AMINO] 3 (1H INDOL 3 YL) 2 METHYLPROPIONAMIDO] 1 PHENYLETHYL]AMINO] 4 OXOBUTYRIC ACID MEGLUMINE; CHOLECYSTOKININ; CHOLECYSTOKININ B RECEPTOR ANTAGONIST;

ANIMAL EXPERIMENT; ARTICLE; CONDITIONING; CONTROLLED STUDY; DOSE RESPONSE; FLEXOR MUSCLE; HINDLIMB; INTRATHECAL DRUG ADMINISTRATION; NERVE CELL EXCITABILITY; NERVE FIBER TRANSECTION; NERVE INJURY; NONHUMAN; PRIORITY JOURNAL; RAT; SCIATIC NERVE; SPINAL REFLEX; WITHDRAWAL REFLEX;

EID: 0031971171     PISSN: 01434179     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0143-4179(98)90020-8     Document Type: Article

References (48)

1. Crawley J N, Corwin R L. Biological actions of cholecystokinin. Peptides 1994; 15: 731-755.
2. Marley P D, Rehfeld J F, Emson P C. Distribution and Chromatographic characterisation of gastrin and cholecystokinin in the rat central nervous system. J Neurochem 1984; 42: 1523-1535.
3. Innis R B, Snyder S H. Distinct cholecystokinin receptors in brain and pancreas. Proc Natl Acad Sci USA 1980; 77: 6917-6921.
4. Moran T, Robinson P, Goldrich M S, McHugh P. Two brain cholecystokinin receptors: implications for behavioural actions. Brain Res 1986; 362: 175-179.
5. Hill D R, Woodruff G N. Differentiation of central cholecystokinin receptor binding sites using the non-peptide antagonist MK-329 and L-365,260. Brain Res 1990; 526: 276-283.
6. Baber N S, Dourish C T, Hill D R. The role of CCK, caerulein, and CCK antagonists in nociception. Pain 1989; 39: 307-328.
7. Wiesenfeld-Hallin Z, Xu X-J. The role of cholecystokinin in nociception, neuropathic pain and opiate tolerance. Regul Pept 1996; 65: 23-28.
8. Schiffmann S N, Vanderhaeghen J-J. Distribution of cells containing mRNA encoding cholecystokinin in the rat central nervous system. J Comp Neurol 1991; 304: 219-233.
9. Cortes R, Arvidsson U, Schalling M, Ceccatelli S. Studies on mRNA for cholecystokinin, calcitonin gene-related peptide and choline acetyltransferase in the lower brain stem, spinal cord and dorsal root ganglia of rat and guinea pig with special reference for motoneurons. J Chem Neuroanat 1990; 3: 467-485.
10. Schiffmann S N, Tengels E, Halleux P, Menu R, Vanderhaeghen J-J. Cholecystokinin mRNA detection in rat spinal cord motoneurons but not in dorsal root ganglia. Neurosci Lett 1991; 123: 123-126.
11. Schultzberg M, Dockray G J, Williams R G. Capsaicin depletes CCK-like immunoreactivity detected by immunohistochemistry, but not that measured by radioimmunoassay in the rat dorsal spinal cord. Brain Res 1982; 235: 198-205.
12. Seroogy K B, Mohapatra N K, Lund P K, Rethelyi M, MacGehee D S, Perl E R. Species-specific expression of cholecystokinin messenger RNA in rodent dorsal root ganglia. Mol Brain Res 1990; 7: 171-176.
13. Verge V M K, Wiesenfeld-Hallin Z, Hökfelt T. Cholecystokinin in mammalian primary sensory neurons and spinal cord: in situ hybridization studies on rat and monkey spinal ganglia. Eur J Neurosci 1992; 5: 240-250.
14. Xu X-J, Puke M J C, Verge V M K, Wiesenfeld-Hallin Z, Hughes J, Hökfelt T. Up-regulation of cholecystokinin in primary sensory neurons is associated with morphine insensitivity in experimental neuropathic pain in the rat. Neurosci Lett 1993; 152: 129-132.
15. Zhang X, Dagerlind A, Elde R P et al. Marked increase in cholecystokinin B receptor messenger RNA levels in rat dorsal root ganglia after peripheral axotomy. Neuroscience 1993; 57: 227-233.
16. Jeftijina S, Miletic V, Randic M. Cholecystokinin octapeptide excites dorsal horn neurons both in vivo and in vitro. Brain Res 1981; 213: 231-236.
17. Rogawski M A, Beinfeld M C, Hayes S E, Hökfelt T, Skirboll L R. Cholecystokinin and cultured spinal neurons. Immunohistochemistry, receptor binding, and neurophysiology. Ann NY Acad Sci 1985; 448: 403-412.
18. Wiesenfeld-Hallin Z, Duranti R. Intrathecal Cholecystokinin interacts with morphine but not substance P in modulating the nociceptive flexion reflex in the rat. Peptides 1987; 8: 153-158.
19. Wall P, Woolf C J. Muscle but not cutaneous C-afferent input produces prolonged increases in the excitability of the flexion reflex in the rat. J Physiol 1984; 356: 443-458.
20. Woolf C J, Swett J E. The cutaneous contribution to the hamstring flexor reflex in the rat: an electrophysiological and anatomical study. Brain Res 1984; 303: 299-312.
21. Woolf C J, Wiesenfeld-Hallin Z. Substance P and calcitonin gene-related peptide synergistically modulate the gain of the nociceptive flexor withdrawal reflex in the rat. Neurosci Lett 1986; 66: 319-323.
22. Chan CWY, Dallaire M. Subjective pain sensation is linearly correlated with the flexion reflex in man. Brain Res 1989; 479: 145-150.
23. Willer J C. Comparative study of perceived pain and nociceptive flexion reflex in man. Pain 1977; 3: 69-80.
24. Woolf C J, McMahon S B. Injury-induced plasticity of the flexor reflex in chronic decerebrate rats. Neuroscience 1985; 16: 395-404.
25. Thompson S W N, King A E, Woolf C J. Activity-dependent changes in rat ventral horn neurons in vitro; summation of prolonged afferent evoked postsynaptic depolarizations produce a D-2-amino-5-phosphonovaleric acid sensitive windup. Eur J Neurosci 1990; 2: 638-649.
26. Woolf C J, Thompson S W N. The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity state. Pain 1991; 44: 293-299.
27. Mendell L M. Physiological properties of unmyelinated fiber projection on the spinal cord. Exp Neurol 1966; 16: 316-332.
28. Hughes J, Boden P, Costall B et al. Development of a class of selective cholecystokinin type B receptor antagonists having potent anxiolytic activity. Proc Natl Acad Sci USA 1990; 87: 6728-6732.
29. Willets J, Urban K, Murase K, Randic M. Actions of cholecystokinin octapeptide on rat spinal dorsal horn neurons In: Vanderhaeghen J, Crawley J C, eds. Neuronal Cholecystokinin. Ann NY Acad Sci 1985; 448: 385-401.
30. Malenka R C, Madison D V, Nicoll R A. Potentiation of synaptic transmission in the hippocampus by phorbol esters. Nature 1986; 321: 175-177.
31. Numann R, William W A, Scheuer T. Functional modulation of brain sodium channels by protein kinase C phosphorylation. Science 1991; 254: 115-118.
32. Swope S L, Moss S J, Blackstone C D, Huganir R L Phosphorylation of ligand-gated ion channels: a possible mode of synaptic plasticity. FASEB J 1992; 6: 2514-2523.
33. Coderre T J, Katz J, Vaccarino A L, Melzack R. Contribution of central neuroplasticity to pathological pain: review of clinical and experimental evidence. Pain 1993; 52: 259-285.
34. Nestler E, Greengard P. Protein phosphorylation in brain. Nature 1997; 305: 583-588.
35. Yashpal K, Pitcher G M, Parent A, Quirion R, Coderre T J. Noxious thermal and chemical stimulation induce increases in 3H-phorbol 12,13-dibutyrate binding in spinal cord dorsal horn as well as persistent pain and hyperalgesia, which is reduced by inhibition of protein kinase C. J Neurosci 1995; 15: 3263-3272.
36. DeReimer S A, Strong J A, Albert K A, Greengard P, Kaczmarek L K. Enhancement of calcium current in Aplysia neurons by phorbol ester and protein kinase C. Nature 1985; 313: 313-316.
37. + currents. Biochem Biophys Res Commun 1986; 134: 1245-1253.
38. Madison D V, Malenka R C, Nicoll R A. Phorbol esters block a voltage-sensitive chloride current in hippocampal cells. Nature 1986; 321: 695-697
39. Mao J, Price D D, Mayer D J, Hayes R L Pain-related increases in spinal cord membrane-bound protein kinase C following peripheral nerve injury. Brain Res 1992; 588: 144-149.
40. Mao J, Mayer D J, Hayes R L, Price D D. Spatial patterns of increased spinal cord membrane-bound protein kinase C and their relation to increases in 14C-2-deoxyglucose metabolic activity in rats with painful peripheral mononeuropathy. J Neurophysiol 1993; 70: 470-481.
41. Wank S A. Cholecystokinin receptors. Am J Physiol 1995; 269: G628-646.
42. Derrien M, Noble F, Maldonado R, Roques, B P. Cholecystokinin-A but not cholecystokinin-B receptor stimulation induces endogenous opioid-dependent antinociceptive effects in the hot plate test in mice. Neurosci Lett 1993; 160: 193-196.
43. Mercer L D, Beart P M. Histochemistry in rat and spinal cord with an antibody directed at the cholecystokinin (A) receptor. Neurosci Lett 1997; 4: 97-100.
44. Woolf C J, Wall P. Relative effectiveness of C primary afferent fibers of different origins in evoking a prolonged facilitation of the flexor reflex in the rat. J Neurosci 1986; 6: 1433-1442.
45. Xu X-J, Dalsgaard C-J, Wiesenfeld-Hallin Z. Intrathecal CP-96,345 blocks reflex facilitation induced in rats by substance P and C-fiber-conditioning stimulation. Eur J Pharmacol 1992; 216: 337-344.
46. Xu X-J, Zhang X, Hökfelt T, Wiesenfeld-Hallin Z. Plasticity in spinal nociception after peripheral nerve section: reduced effectiveness of the NMDA receptor antagonist MK-801 in blocking wind-up and central sensitization of the flexor reflex. Brain Res 1995; 670: 342-346.
47. Wiesenfeld-Hallin Z, Xu X-J, Håkanson R, Feng D-M, Folkers K. Plasticity of the peptidergic mediation of spinal reflex facilitation after peripheral nerve section in the rat. Neurosci Lett 1990; 116: 293-298.
48. + in rats with intact and axotomized sciatic nerves or peripheral inflammation: a microdialysis study. Soc Neurosci Abstr 1997; 23: 1537.