Heat shock proteins as potential targets in the therapy of inflammatory arthritis

Biotherapy

Volumn 10, Issue 3, 1998, Pages 197-203

  Gaston, J S H ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Arthritis; Autoimmunity; Heat shock protein; Immunomodulation; T lymphocyte

Indexed keywords

HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 60;

ARTHRITIS; ARTICLE; AUTOIMMUNE DISEASE; CROSS REACTION; HUMAN; IMMUNIZATION; MEMORY CELL; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0031971150     PISSN: 0921299X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02678297     Document Type: Article

References (54)

1. Hennann E, Lohse AW, van der Zee R, van Eden W, Mayet WJ, Probst P, Poralla T, MeyeizumBuschenfelde KH, Fleischer B. Synovial fluid derived Yersinia reactive T cells responding to human 65 kDa heat shock protein and heat stressed antigen presenting cells. Eur J Immunol 1991; 21: 2139.
2. Gaston JSH, Deane KHO, Jecock RM, Pearce JH. Identification of two Chlamydia trachomatis antigens recognized by synovial fluid T cells from patients with Chlamydia induced reactive arthritis. J Rheumatol 1996; 23: 130.
3. Gaston J, Young J, Ramsey S, and Scott D. Specificity of synovial fluid T cells in iatrogenic human adjuvant arthritis. Arthritis Rheum 1996; 39: S149.
4. Kaufmann SHE. Immunity to Intracellular Bacteria. Annu Rev Immunol 1993; 11: 129.
5. Morrison R, Beiland R, Lyng K, Caldwell H. Chlamydial disease pathogenesis. The 57 kD chlamydial hypersensitivity antigen is a stress response protein. J Exp Med 1989; 170: 1271.
6. Witkin SS, Jeremias J, Toth M, Ledger WJ. Proliferative response to conserved epitopes of the Chlamydia trachomatis and human 60-kilodalton heat-shock proteins by lymphocytes from women with salpingitis. American Journal of Obstetrics and Gynecology 1994; 171: 455.
7. Dieterle S, Wollenhaupt J. Humoral immune response to the chlamydial heat shock proteins hsp60 and hsp70 in Chlamydiaassociated chronic salpingitis with tubal occlusion. Hum Reprodl996;ll: 1352.
8. Peeling R, Kimani J, Plummer F, Maclean I, Cheang M, Bwayo J, Brunham R. Antibody to Chlamydial hsp60 predicts an increased risk for chlamydial pelvic inflammatory disease. J Infect Dis 1997; 175: 1153.
9. Beatty WL, Byrne GI, Morrison RP. Morphologic and antigenie characterization of Interferon gamma-mediated persistent chlamydia-trachomatis infection in vitro. Proc Natl Acad Sei (USA) 1993; 90: 3998.
10. Beatty WL, Morrison RP, Byme GI. Persistent chlamydiae: From cell culture to a paradigm for chlamydial pathogenesis. Microbiological Reviews 1994; 58: 686.
11. Lopezguerrero JA, Ortiz MA, Paez E, Bemabeu C, Lopezbote JP. Therapeutic effect of recombinant vaccinia virus expressing the 60-kd heat-shock protein on adjuvant arthritis. Arthritis Rheum 1994; 37: 1462.
12. Ragno S, Colston MJ, Lowrie DB, Winrow VR, Blake DR, Tascon R. Protection of rats from adjuvant arthritis by immunization with naked DNA encoding for mycobacterial heat shock protein 65. Arthritis Rheum 1997; 40: 277.
13. Silva CL, Lowrie DB. A single mycobacterial protein (hsp 65) expressed by a transgenic antigen-presenting cell vaccinates mice against tuberculosis. Immunology 1994; 82: 244.
14. Tonnetti L, Spaccapelo R, Cenci E, Menacel A. Puccetti P, Coffman R, Bistoni F, Roman Li. Interleukin-4 and interleukin10 exacerbate candidiasis in mice. Eur J Immunol 1995; 25: 1559.
15. Reiner S, Locksley R. The regulation of immunity to Leishmania major. Annu Rev Immunol 1995; 13: 151.
16. Johansson M, Schon K, Ward M, Lycke N. Genital tract infection with Chlamydia trachomatis fails to induce protective immunity in gamma interferon receptor- deficient mice despite a strong local immunoglobulin A response. Infect Immun 1997; 65: 1032.
17. Perry LL, Feilzer K, Caldwell HD. Immunity to Chlamydia trachomatis is mediated by T helper 1 cells through IFN-gammadependent and -independent pathways. J Immunol 1997; 158: 3344.
18. Paul WE, Seder RA. Lymphocyte Responses and Cytokines. Cell 1994; 76: 241.
19. SloanLancaster J, Alien P. Altered peptide ligand-induced partial T cell activation. Annu Rev Immunol 1996; 14: 1.
20. Pfeiffer C, Stein J, Southwood S, Ketelaar H, Seite A, Bottomry K. Altered peptide ligands can control CD4 T lymphocyte differentiation in vivo. J Exp Med 1995; 181: 1569.
21. Wauben M, Boog C, van der Zee R, Joosten I, Schlief A, van Eden W. Disease inhibition by major histocompatibility complex binding peptide analogues of disease-associated epitopes: more than blocking alone. J Exp Med 1992; 176: 667.
22. Strober S, Tanay A, Field E, Hoppe RT, Calin A, Engleman EG, Kotzin B, Brown BW, Kaplan HS. Efficacy of total lymphoid irradiation in intractable rheumatoid arthritis. Ann Intern Med 1985; 102: 441.
23. Isaacs J, Watts R, Hazleman B, Hale G, Waldmann H. Humanised monoclonal antibody therapy for rheumatoid arthritis. Lancet 1992; 340: 748.
24. Falcone M, Bloom BR. A T helper cell 2 (Th2) immune response against non-self antigens modifies the cytokine profile of autoimmune T cells and protects against experimental allergic encephalomyelitis. J Exp Med 1997; 185: 901.
25. Quayle AJ, Black WK, Li SO, Kjeldson-Kragh J, Oftung F, Sioud M, Forre O, Capra D, Natvig JB. Peptide recognition, T cell receptor usage and HLA restriction of human heat-shock protein 60 and mycobacterial 65-kDa hsp-reactive T cell clones from rheumatoid synovial fluid. EurJImmunol 1992; 22: 1315.
26. Van Eden W, Thole J, van der Zee R, Noordzij A, van Embden J, Hensen E, Cohen I. Cloning of the mycobacterial epitope recognized by T lymphocytes in adjuvant arthritis. Nature 1988; 331, no. 6152: 171.
27. Van Eden W, Hogervorst E, Hensen E, van der Zee R, van Embden J, Cohen I. A cartilage mimicking T cell epitope on a 65K mycobacterial heat shock protein: adjuvant arthritis as a model for human rheumatoid arthritis. Curr Top Microbiol Immunol 1989; 145: 27-43.
28. Wucherpfennig KW, Strominger JL. Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein. Cell 1995; 80 5: 695.
29. Barnaba V, Sinigagli F. Molecular mimicry and T cell mediated autoimmune disease. J Exp Med 1997; 185: 1529.
30. Thompson S, Rook G, Brealey R, van der Zee R, Elson C. Autoimmune reactions to heat shock proteins in pristane induced arthritis. Eur J Immunol 1990; 20: 2479.
31. Elson CJ, Thompson SJ. Immunity, autoimmunity and immunotherapy: New frontiers in heat shock protein research. Clin Exp Immunol 1994; 98: 175.
32. Lehmann P, Forsthuber T, Miller A, Sercarz E. Spreading of T cell autoimmunity to cryptic determinants of an autoantigen. Nature 1992; 358: 155.
33. Lehmann PV, Sercarz EE, Forsthuber T, Dayan CM, Gammon G. Determinant spreading and the dynamics of the autoimmune T-cell repertoire. Immunol Today 1993; 14: 203.
34. Moudgil K, Chang T, Bradât H, Chen A, Gupta R, Brahn E, Sercarz E. Diversification of T cell responses to carboxyterminal determinants within the 65-kD heat shock protein is involved in regulation of autoimmune arthritis. J Exp Med 1997; 185: 1307.
35. Thompson SJ, Elson CJ. Susceptibility to pristane-induced arthritis is altered with changes in bowel flora. Immunology Letters 1993; 36: 227.
36. Elson CJ, Barker RN, Thompson SJ, Williams NA. Immnnologioally ignorant autoreactive T cells, epitope spreading and repertoire limitation. Immunol Today 1995; 16: 71.
37. Racke M, Bonomo A, Scott D, Cannella B, Levine A, Raine C, Shevach E, Rocken M. Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease. J Exp Med 1994; 180: 1961.
38. Segal B, Klinman D, Shevach E. Microbial products induce autoimmune disease by an IL-12-dependent pathway. J Immunol 1997; 185: 5087.
39. Billingham M, Carney S, Butler R, Colston M. A mycobacterial 65 kD heat shock protein induces antigen specific suppression of adjuvant arthritis, but is not itself arthritogenic. J Exp Med 1990; 171: 339.
40. Van Den Broek M, Hogervorst E, BM, van Bruggen M, van Eden W, van der Zee R, van den Berg W. Protection against streptococcal cell wall induced arthritis by pretreatment with the 65 kD mycobacterial heat shock protein. J Exp Med 1989; 170: 449.
41. Änderten SM, van der Zee R, Prakken B, Noordzij A, van Eden W. Activation of T cells recognizing self 60-kD heat shock protein can protect against experimental arthritis. J Exp Med 1995; 181:943.
42. Powrie F, Correaoliveira R, Mauze S, Coffman RL. Regulatory interactions between Cd45Rb(High) and Cd45Rb(Low) CD4(+) T cells are important for the balance between protective and pathogenic cell-mediated immunity. J Exp Med 1994; 179: 589.
43. Leach M, Bean A, Mauze S, Coffman R, Powrie F. Inflammatory bowel disease in C.B-17 seid mice reconstituted with the CD45RBhigh subset of CD4+ T cells. Am JPathol 1996; 148: 1503.
44. Birk O, Douek D, Elias D, Takacs K, Dewchand H, Our S, Walker M, van der Zee R, Cohen I, Altmann D. A role of hspoO in autoimmune diabetes: Analysis in a transgenic model. Proc Natl Acad Sei (USA) 1996; 93: 1032.
45. Benoist C, Mathis D. Positive selection of T cells: fastidious or promiscuous? Curr Opin Immunol 1997; 9: 245.
46. DeGraeff-Meeder E, Voorhorst M, van Eden W, Schuurman H, Huber J, Barkley D, Maini R, Kuis W, Rijkers G, Zegers B. Antibodies to the mycobacterial 65 kd heat shock protein are reactive with synovial tissue of adjuvant arthritic rats and patients with rheumatoid arthritis and osteoarthritis. Am J Pathol 1990; 137: 1013.
47. Boog CJP, DeGraeff-Meeder ER, Lucassen MA, van der Zee R, Voorhorst Ogink MM, van Kooten PJS, Geuze HJ, van Eden W. Two monoclonal antibodies generated against human hspoO show reactivity with synovial membrane of patients with juvenile chronic arthritis. J Exp Med 1992; 175:1805.
48. Prakken A, van Eden W, Rijkers G, Kuis W, Toebes E, De Graeff-Meeder E, van der Zee R, Zegers B. Autoreactivity to human heat shock protein 60 predicts disease remission in oligoarticular juvenile rheumatoid arthritis. Arthritis Rheum 1996; 39: 1826.
49. Ramage J, Young J, Goodall J, Gaston J. Proliferative responses of 'naive' and 'primed' human T cells subsets. Arthritis Rheum 1996; 39: S265.
50. Burkly L, Lo D, Kanagawa O, Brinster R, Flavell R. T cell tolerance by clonal anergy in transgenic mice with nonlymphoid expression of MHC class III E. Nature 1989; 342: 6249: 564.
51. O'Hehir R, Lamb J. Induction of specific clonal anergy in human T lymphocytes by Staphylococcus aureus enterotoxins. Proc Natl Acad Sei USA 1990; 87,22: 8884.
52. Sloanlancaster J, Evavold BD, Alien PM. Induction of Tcell energy by altered T-cell-receptor ligand on live antigenpresenting cells. Nature 1993; 363, 6425: 156.
53. Rahelu M, Williams GT, Kumararatne DS, Eaton GC, Gaston JSH. Human CD4+ cytolytic T-cells kill antigen-pulsed target T-cells by induction of apoptosis. J Immunol 1993; 150, 11: 4856.
54. Alderson MR, Tough TW, Davissmith T, Braddy S, Falk B, Schooley KA, Goodwin RG, Smith ÇA, Ramsdell F, Lynch DH. Fas ligand mediates activation-induced cell death in human T lymphocytes. J Exp Med 1995; 181, 1: 71.