Use of the comet test in the evaluation of multidrug resistance of human cell lines

Leukemia

Volumn 12, Issue 4, 1998, Pages 627-632

  Mattii, L ^a   Barale, R ^a   Petrini, M ^a,b  

^a UNIVERSITY OF PISA   (Italy)

^b UNIVERSITY OF PISA   (Italy)

Author keywords

Chemoresistance; Comet test; DNA damage; Multidrug resistance

Indexed keywords

AMBAMUSTINE; DAUNORUBICIN; VERAPAMIL; VINBLASTINE;

ARTICLE; CELL LINE; CELL STRAIN HL 60; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; TUMOR CELL CULTURE;

EID: 0031970374     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2400976     Document Type: Article

References (18)

1. Kartner N, Shales M, Riordan JR, Ling V. DNR-resistant Chinese hamster ovary cells expressing multidrug resistance and a cell surface P-glycoprotein. Cancer Res 1983; 43: 222-228.
2. Carulli G, Petrini M. Multidrug resistance: focus in haematology. Haematologica 1990; 75: 363-374.
3. Danks MK, Yalowich JC, Beck WT. Atypical multiple drug resistance in a human leukaemia cell line selected for resistance to teniposide (VM-26). Cancer Res 1987; 47: 1297-1301.
4. Cole SPC, Bhardwaj G, Gerlach JH, Mackie JE, Grant CE, Almquist KC, Stewart AJ, Kurz EU, Duncan AMV, Deeley RG. Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line. Science 1992; 258: 1650-1654.
5. Sheper RJ, Broxterman HJ, Scheffer GL et al. Overexpression of a M(r) 110000 vesicular protein in non-P-glycoprotein-mediated multidrug resistance. Cancer Res 1993; 53: 1475-1479.
6. Ostling O, Johanson KJ. Microelectrophoretic study of radiation-induced DNA damage in individual mammalian cells. Biochem Biophys Res Commun 1984; 123: 291-298.
7. Singh NP, McCoy MT, Tice RR, Schneider EL. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res 1988; 175: 184-191.
8. Olive PL, Banath JP, Durand RE. Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cell measured using 'comet' assay. Radiat Res 1990; 122: 86-94.
9. Pool-Zobel BL, Lambertz R, Knoll M, Schmetzer P. Detection of genotoxicity in cells of the gastrointestinal tract. Mutagenesis 1992; 7: 166-173.
10. McKelvey-Martin VJ, Green MHL, Schmetzer P, Pool-Zobel BL, De Meo MP, Collins A. The single cell gel electrophoresis assay (comet assay): a European review. Mutat Res 1993; 288: 47-63.
11. Zhou DC, Marie JP, Maisonneuvre L, Fassaut-Suberville AM, Zittoun R. Effect of differentiating agents on modulation of MDR1 gene expression in multidrug-resistant hematopoietic HL60/DNR cell line. Exp Hematol 1993; 21: 779-784.
12. Cianfriglia M, Yassen A, Tombesi M, Samoggia P, Barca S, Caserta M. Expression of lymphocyte homing receptor gene is lost in multi-drug-resistant variants of human T-lymphoblastoid CCRF-CEM Int J Cancer 1991; 49: 394-397.
13. Sheper RJ, Bulte JW, Brakkee JG, Quak JJ, Shoot E, van der Balm AJ, Meijer CJ, Broxterman HJ, Kuiper CM, Lankelma J, Pinedo HM. Monoclonal antibody JSB-1 delects a highly conserved epitope on the P-glycoprotein associated with multidrug resistance. Int J Cancer 1988; 42: 389-394.
14. Cianfriglia M, Willingham MC, Tombesi M, Scagliotti GV, Frasca G, Chersi A. P-glycoprotein epitope mapping. Identification of a linear human specific epitope in the fourth loop of the P-glycoprotein extracellular domain by MM 4.17 murine monoclonal antibody to human multi-drug-resistant cells. Int J Cancer 1994; 56: 153-160.
15. Sabbatini ARM, Basolo F, Valentini P, Mattii L, Calvo S, Fiore L, Petrini M. Induction of multidrug resistance (MDR) by transfection of MCF-10A cell line with c-Ha-ras and c-erbB-2 oncogenes. Int J Cancer 1994; 59: 1-4.
16. Beck WT, Gorgan TM, William CL, Cordon-Cardo C, Parham D, Kuttesch JF, Andreeff M, Bates SE, Bernard CW, Boyett JM, Brophy NA, Broxterman HJ, Chan HSL, Dalton WS, Dietel M, Fojo A, Gasconye RD, Head D, Houghton PJ, Srivastava DK, Lehnert M, Leith C, Paietta E, Pavelic ZP, Rimza L, Roninson IB, Sikic BI, Twentyman PR, Warnke R, Weinstein R. Methods to detect P-gly-coprotein-associated multidrug resistance in patients' tumors: consensus recommendations. Cancer Res 1996; 56: 3010-3020.
17. Cooper MR. Principles of medical oncology. In: Holleb AI, Fink D), Murphy GP (eds). American Cancer Society Textbook of Clinical Oncology. American Cancer Society: Atlanta, GA, 1991, pp 47-68.
18. De Barbieri A, Dall'Asta L, Comini A, Springolo V, Mosconi P, Coppi G. Synthesis, acute toxicity and chemotherapeutic anticancer activities of a new tripeptide mustard. Farmaco (SCI) 1983; 38: 205-218.