메뉴 건너뛰기




Volumn 63, Issue 4, 1998, Pages 429-439

Trypanosoma brucei infection elicits nitric oxide-dependent and nitric oxide-independent suppressive mechanisms

Author keywords

Immunosuppression; Interferon deficient mice; Myeloid precursor cells; Trypanosoma brucei brucei

Indexed keywords

GAMMA INTERFERON; NITRIC OXIDE;

EID: 0031969369     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlb.63.4.429     Document Type: Article
Times cited : (51)

References (34)
  • 1
    • 0022555868 scopus 로고
    • Discontinuous transcription and antigenic variation in trypanosomes
    • Borst, P. (1986) Discontinuous transcription and antigenic variation in trypanosomes. Annu. Rev. Biochem. 55, 701-732.
    • (1986) Annu. Rev. Biochem. , vol.55 , pp. 701-732
    • Borst, P.1
  • 3
    • 0026048845 scopus 로고
    • The role of macrophage in induction of immunosuppression in Trypanosoma congolense-infected cattle
    • Flynn, J. N., Sileghem, M. (1991) The role of macrophage in induction of immunosuppression in Trypanosoma congolense-infected cattle. Immunology 74, 310-316.
    • (1991) Immunology , vol.74 , pp. 310-316
    • Flynn, J.N.1    Sileghem, M.2
  • 4
    • 2642610627 scopus 로고
    • Immunobiology of African trypanosomiasis in laboratory rodents
    • (I. Tizard, ed.), Boca Raton, FL: CRC Press
    • Bancroft, G., Askonas, B. A. (1985) Immunobiology of African trypanosomiasis in laboratory rodents. In Immunology and Pathogenesis of Trypanosomiasis (I. Tizard, ed.), Boca Raton, FL: CRC Press, 75-102.
    • (1985) Immunology and Pathogenesis of Trypanosomiasis , pp. 75-102
    • Bancroft, G.1    Askonas, B.A.2
  • 5
    • 0021982624 scopus 로고
    • Macrophages as mediators of immunosuppression in murine African trypanosomiasis
    • Askonas, B. A. (1985) Macrophages as mediators of immunosuppression in murine African trypanosomiasis. Curr. Top. Microbiol. Immunol. 117, 119-127.
    • (1985) Curr. Top. Microbiol. Immunol. , vol.117 , pp. 119-127
    • Askonas, B.A.1
  • 6
    • 0024397998 scopus 로고
    • Modulation of IL-1 production and IL-1 release during experimental trypanosome infentions
    • Sileghem, M., Darji, A., Hamers, R., De Baetselier, P. (1989) Modulation of IL-1 production and IL-1 release during experimental trypanosome infentions. Immunology 68, 137-139.
    • (1989) Immunology , vol.68 , pp. 137-139
    • Sileghem, M.1    Darji, A.2    Hamers, R.3    De Baetselier, P.4
  • 7
    • 0025347631 scopus 로고
    • Suppressive macrophages occurring in murine T. brucei infection inhibit T cell responses in vivo and in vitro
    • Borrowy, N. K., Sternberg, J. M., Schreiber, D., Nonnengaesser, C., Overath, P. (1990) Suppressive macrophages occurring in murine T. brucei infection inhibit T cell responses in vivo and in vitro. Parasite Immunol. 12, 233-246.
    • (1990) Parasite Immunol. , vol.12 , pp. 233-246
    • Borrowy, N.K.1    Sternberg, J.M.2    Schreiber, D.3    Nonnengaesser, C.4    Overath, P.5
  • 8
    • 0026043531 scopus 로고
    • Suppression by Trypanosoma brucei rhodesiense of the capacities of human T lymphocytes to express interleukin-2 receptors and proliferate after mitogenic stimulation
    • Kierzenbaum, F., Muthukkumar, S., Beltz, L. A., Sztein, M. B. (1991) Suppression by Trypanosoma brucei rhodesiense of the capacities of human T lymphocytes to express interleukin-2 receptors and proliferate after mitogenic stimulation. Infect. Immun. 59, 3518-3522.
    • (1991) Infect. Immun. , vol.59 , pp. 3518-3522
    • Kierzenbaum, F.1    Muthukkumar, S.2    Beltz, L.A.3    Sztein, M.B.4
  • 9
    • 0024538690 scopus 로고
    • Different mechanisms account for the suppression of interleukin 2 production and the suppression of interleukin 2 receptor expression in Trypanosoma brucei-infected mice
    • Sileghem, M., Darji, A., Remels, L., Hamers, R., De Baetselier, P. (1989) Different mechanisms account for the suppression of interleukin 2 production and the suppression of interleukin 2 receptor expression in Trypanosoma brucei-infected mice. Eur. J. Immunol. 19, 119-124.
    • (1989) Eur. J. Immunol. , vol.19 , pp. 119-124
    • Sileghem, M.1    Darji, A.2    Remels, L.3    Hamers, R.4    De Baetselier, P.5
  • 10
    • 0024336562 scopus 로고
    • Dual role of macrophages in the suppression of interleukin 2 production and interleukin 2 receptor expression in Trypanosome-infected mice
    • Sileghem, M., Darji, A., Hamers, R., Van De Winkel, M., De Baetselier, P. (1989) Dual role of macrophages in the suppression of interleukin 2 production and interleukin 2 receptor expression in Trypanosome-infected mice. Eur. J. Immunol. 19, 829-835.
    • (1989) Eur. J. Immunol. , vol.19 , pp. 829-835
    • Sileghem, M.1    Darji, A.2    Hamers, R.3    Van De Winkel, M.4    De Baetselier, P.5
  • 11
    • 0023616521 scopus 로고
    • Experimental Trypanosoma brucei infections selectively suppress both interleukin 2 production and interleukin 2 receptor expression
    • Sileghem, M., Hamers, R., De Baetselier, P. (1987) Experimental Trypanosoma brucei infections selectively suppress both interleukin 2 production and interleukin 2 receptor expression. Eur. J. Immunol. 17, 1417-1421.
    • (1987) Eur. J. Immunol. , vol.17 , pp. 1417-1421
    • Sileghem, M.1    Hamers, R.2    De Baetselier, P.3
  • 12
    • 0027177154 scopus 로고
    • Inhibition of T cell responsiveness during experimental infections with Trypanosoma brucei: Active involvement of endogenous gamma interferon
    • Darji, A., Sileghem, M., Heremans, H., Brys, L., De Baetselier, P. (1993) Inhibition of T cell responsiveness during experimental infections with Trypanosoma brucei: active involvement of endogenous gamma interferon. Infect. Immun. 61, 3098-3102.
    • (1993) Infect. Immun. , vol.61 , pp. 3098-3102
    • Darji, A.1    Sileghem, M.2    Heremans, H.3    Brys, L.4    De Baetselier, P.5
  • 13
    • 0026788352 scopus 로고
    • Nitric oxide mediates suppression of T cell responses in murine Trypanosoma brucei infection
    • Sternberg, J., Mc Guigan, F. (1992) Nitric oxide mediates suppression of T cell responses in murine Trypanosoma brucei infection. Eur. J. Immunol. 22, 2741-2744.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 2741-2744
    • Sternberg, J.1    Mc Guigan, F.2
  • 14
    • 0027382922 scopus 로고
    • Suppressor macrophages in African trypanosomiasis inhibit T cell proliferative responses by nitric oxide and prostaglandins
    • Schleifer, K. W., Mansfield, J. M. (1993) Suppressor macrophages in African trypanosomiasis inhibit T cell proliferative responses by nitric oxide and prostaglandins. J. Immunol. 151, 5492-5503.
    • (1993) J. Immunol. , vol.151 , pp. 5492-5503
    • Schleifer, K.W.1    Mansfield, J.M.2
  • 15
    • 0029925710 scopus 로고    scopus 로고
    • Nitric oxide-mediated suppression of T cell responses during Trypanosoma brucei infection: Soluble trypanosome products and interferon-γ are synergistic inducers of nitric oxide synthase
    • Sternberg, J. M., Mabbott, N. A. (1996) Nitric oxide-mediated suppression of T cell responses during Trypanosoma brucei infection: soluble trypanosome products and interferon-γ are synergistic inducers of nitric oxide synthase. Eur. J. Immunol. 26, 539-543.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 539-543
    • Sternberg, J.M.1    Mabbott, N.A.2
  • 16
    • 0028027963 scopus 로고
    • Trypanosoma brucei is protected from the cytostatic effects of nitric oxide under in vivo conditions
    • Mabbott, N. A., Sutherland, I. A., Sternberg, J. M. (1994) Trypanosoma brucei is protected from the cytostatic effects of nitric oxide under in vivo conditions. Parasitol. Res. 80, 687-690.
    • (1994) Parasitol. Res. , vol.80 , pp. 687-690
    • Mabbott, N.A.1    Sutherland, I.A.2    Sternberg, J.M.3
  • 17
    • 0030006457 scopus 로고    scopus 로고
    • In vitro simulation of immunosuppression caused by Trypanosoma brucei: Active involvement of gamma interferon and tumor necrosis factor in the pathway of suppression
    • Darji, A., Beschin, A., Sileghem, M., Heremans, H., Brys, L., De Baetselier, P. (1996) In vitro simulation of immunosuppression caused by Trypanosoma brucei: active involvement of gamma interferon and tumor necrosis factor in the pathway of suppression. Infect. Immun. 64, 1937-1943.
    • (1996) Infect. Immun. , vol.64 , pp. 1937-1943
    • Darji, A.1    Beschin, A.2    Sileghem, M.3    Heremans, H.4    Brys, L.5    De Baetselier, P.6
  • 19
    • 0028949134 scopus 로고
    • Suppressor macrophages in Trypanosoma brucei infection: Nitric oxide is related to both suppressive activity and lifespan in vivo
    • Mabbott, N. A., Sutherland, I. A., Sternberg, J. M. (1995) Suppressor macrophages in Trypanosoma brucei infection: nitric oxide is related to both suppressive activity and lifespan in vivo. Parasite Immunol. 17, 143-150.
    • (1995) Parasite Immunol. , vol.17 , pp. 143-150
    • Mabbott, N.A.1    Sutherland, I.A.2    Sternberg, J.M.3
  • 20
    • 0028231232 scopus 로고
    • Inhibition of nitric oxide synthesis leads to reduced parasitemia in murine Trypanosoma brucei infection
    • Sternberg, J., Mabbott, N., Sutherland, I., Liew, F. Y. (1994) Inhibition of nitric oxide synthesis leads to reduced parasitemia in murine Trypanosoma brucei infection. Infect. Immun. 62, 2135-2137.
    • (1994) Infect. Immun. , vol.62 , pp. 2135-2137
    • Sternberg, J.1    Mabbott, N.2    Sutherland, I.3    Liew, F.Y.4
  • 21
    • 0029822219 scopus 로고    scopus 로고
    • Nitric oxide synthesis is depressed in Bos indicus cattle infected with Trypanosoma congolense and Trypanosoma vivax and does not mediate T cell suppression
    • Taylor, K., Lutje, V., Mertens, B. (1996) Nitric oxide synthesis is depressed in Bos indicus cattle infected with Trypanosoma congolense and Trypanosoma vivax and does not mediate T cell suppression. Infect. Immun. 64, 4115-4122.
    • (1996) Infect. Immun. , vol.64 , pp. 4115-4122
    • Taylor, K.1    Lutje, V.2    Mertens, B.3
  • 22
    • 0028348042 scopus 로고
    • Mitogen- and antigen-specific proliferation of T cells in murine toxoplasmosis is inhibited by reactive nitrogen intermediates
    • Candolfi, E., Hunter, C. A., Remington, J. S. (1994) Mitogen- and antigen-specific proliferation of T cells in murine toxoplasmosis is inhibited by reactive nitrogen intermediates. Infect. Immun. 62, 1995-2001.
    • (1994) Infect. Immun. , vol.62 , pp. 1995-2001
    • Candolfi, E.1    Hunter, C.A.2    Remington, J.S.3
  • 23
    • 0028913754 scopus 로고
    • Roles of gamma interferon and other cytokines in suppression of the spleen cell proliferative response to concanavalin A and toxoplasma antigen during acute toxoplasmosis
    • Candolfi, E., Hunter, C. A., Remington, J. S. (1995) Roles of gamma interferon and other cytokines in suppression of the spleen cell proliferative response to concanavalin A and toxoplasma antigen during acute toxoplasmosis. Infect. Immun. 63, 751-756.
    • (1995) Infect. Immun. , vol.63 , pp. 751-756
    • Candolfi, E.1    Hunter, C.A.2    Remington, J.S.3
  • 26
    • 0028339888 scopus 로고
    • Modulation of T cell responsiveness during Trypanosoma cruzi infection: Analysis in different lymphoid compartments
    • Vandekerckove, F., Darji, A., Rivera, M.-T., Carlier, Y., Vray, B., Billiau, A., De Baetselier, P. (1994) Modulation of T cell responsiveness during Trypanosoma cruzi infection: analysis in different lymphoid compartments. Parasite Immunol. 16, 77-85.
    • (1994) Parasite Immunol. , vol.16 , pp. 77-85
    • Vandekerckove, F.1    Darji, A.2    Rivera, M.-T.3    Carlier, Y.4    Vray, B.5    Billiau, A.6    De Baetselier, P.7
  • 28
    • 0029884316 scopus 로고    scopus 로고
    • Induction of interferon-gamma, transforming growth factor-beta, and interleukin-4 in mouse strains with different susceptibilities to Trypanosoma brucei brucei
    • Bakhiet, M., Olsson, T., Ljungdahl, A., Höjeberg, B., Vander Meide, P., Kristensson, K. (1996) Induction of interferon-gamma, transforming growth factor-beta, and interleukin-4 in mouse strains with different susceptibilities to Trypanosoma brucei brucei. J. Interferon Cytokine Res. 16, 427-433.
    • (1996) J. Interferon Cytokine Res. , vol.16 , pp. 427-433
    • Bakhiet, M.1    Olsson, T.2    Ljungdahl, A.3    Höjeberg, B.4    Vander Meide, P.5    Kristensson, K.6
  • 29
    • 0019191207 scopus 로고
    • Host genotype influences immunomodulation by interferon
    • De Mayer, E., De Maeyer-Guignard, J. (1980) Host genotype influences immunomodulation by interferon. Nature 284, 173-175.
    • (1980) Nature , vol.284 , pp. 173-175
    • De Mayer, E.1    De Maeyer-Guignard, J.2
  • 30
    • 0026017823 scopus 로고
    • Macrophage cytostatic effect on Trypanosoma musculi involves an L-arginine-dependent mechanism
    • Vincendeau, P., Dalouède, S. (1991) Macrophage cytostatic effect on Trypanosoma musculi involves an L-arginine-dependent mechanism. J. Immunol. 146, 4338-4343.
    • (1991) J. Immunol. , vol.146 , pp. 4338-4343
    • Vincendeau, P.1    Dalouède, S.2
  • 31
    • 0027761439 scopus 로고
    • The role of nitric oxide in parasitic diseases
    • Liew, F. Y. (1993) The role of nitric oxide in parasitic diseases. Ann. Trop. Med. Parasitol. 87, 637-642.
    • (1993) Ann. Trop. Med. Parasitol. , vol.87 , pp. 637-642
    • Liew, F.Y.1
  • 32
    • 0028093591 scopus 로고
    • Nitric oxide-mediated antiplasmodial activity in human and murine hepatocytes induced by gamma interferon and the parasite itself: Enhancement by exogenous tetrahydrobiopterin
    • Mellouk, S., Hoffman, S. L., Liu, Z. Z., De La Vega, P., Billiar, T. R., Nussler, A. K. (1994) Nitric oxide-mediated antiplasmodial activity in human and murine hepatocytes induced by gamma interferon and the parasite itself: enhancement by exogenous tetrahydrobiopterin. Infect. Immun. 62, 4043-4046.
    • (1994) Infect. Immun. , vol.62 , pp. 4043-4046
    • Mellouk, S.1    Hoffman, S.L.2    Liu, Z.Z.3    De La Vega, P.4    Billiar, T.R.5    Nussler, A.K.6
  • 33
    • 0030053630 scopus 로고    scopus 로고
    • In vivo regulation of nitric oxide production by tumor necrosis factor alpha and gamma interferon, but not by interleukin-4, during blood stage malaria in mice
    • Jacobs, P., Radzioch, D., Stevenson, M. M. (1996) In vivo regulation of nitric oxide production by tumor necrosis factor alpha and gamma interferon, but not by interleukin-4, during blood stage malaria in mice. Infect. Immun. 64, 44-49.
    • (1996) Infect. Immun. , vol.64 , pp. 44-49
    • Jacobs, P.1    Radzioch, D.2    Stevenson, M.M.3
  • 34
    • 0025877717 scopus 로고
    • Immunosuppression induced by attenuated Salmonella: Evidence for mediation by macrophage precursors
    • Al-Ramadi, B. K., Brodkin, M. A., Mosser, D. M., Eisenstein, T. K. (1991) Immunosuppression induced by attenuated Salmonella: Evidence for mediation by macrophage precursors. J. Immunol. 146, 2737-2746.
    • (1991) J. Immunol. , vol.146 , pp. 2737-2746
    • Al-Ramadi, B.K.1    Brodkin, M.A.2    Mosser, D.M.3    Eisenstein, T.K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.