Failure of Kupffer cell blockade to prevent disseminated intravascular coagulation in endotoxemic rats despite improved survival

Langenbeck's Archives of Surgery

Volumn 383, Issue 1, 1998, Pages 75-80

  Rüttinger, Dominik ^a   Vollmar, Brigitte ^b   Kempter, Bernhard ^c   Messmer, Konrad ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

Author keywords

Disseminated intravascular coagulation; Gadolinium chloride; Kupffer cell; Lipopolysaccharide; Tumor necrosis factor

Indexed keywords

ANTITHROMBIN III; BLOOD CLOTTING FACTOR 12; BLOOD CLOTTING FACTOR 5; BLOOD CLOTTING FACTOR 7; FIBRINOGEN; GADOLINIUM CHLORIDE; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISSEMINATED INTRAVASCULAR CLOTTING; DRUG EFFECT; ENDOTOXEMIA; INTRAVENOUS DRUG ADMINISTRATION; KUPFFER CELL; MALE; MORTALITY; NONHUMAN; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; RAT; SURVIVAL; THROMBOCYTE COUNT;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BLOOD COAGULATION FACTORS; BLOOD COAGULATION TESTS; DISSEMINATED INTRAVASCULAR COAGULATION; ENDOTOXEMIA; ESCHERICHIA COLI; GADOLINIUM; KUPFFER CELLS; LIPOPOLYSACCHARIDES; MALE; MULTIPLE ORGAN FAILURE; PHAGOCYTOSIS; RATS; RATS, SPRAGUE-DAWLEY; SURVIVAL ANALYSIS;

EID: 0031969250     PISSN: 14352443     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004230050095     Document Type: Article

References (34)

1. Beaser SB, Segel A, Vandam L (1942) The anticoagulant effects in rabbits and man of the intravenous injection of salts of rare earths. J Clin Invest 21:447
2. Biozzi G, Stiffel C (1965) The physiopathology of the reticuloendothelial cells of the liver and spleen. Prog Liver Dis 6:166
3. 2+ flux as initial event in phagocytosis by rat Kupffer cells. Eur J Biochem 131:539
4. Clauss A (1957) Gerinnungsphysiologische Schnellmethode zur Bestimmung des Fibrinogens. Acta Haematol 17:237
5. Conkling PR, Greenberg CS, Weinberg JB (1988) Tumor necrosis factor induces tissue factor-like activity in human leukemia cell line U937 and peripherial blood monocytes. Blood 72:128
6. Decker K (1990) Biologically active products of stimulated liver macrophages (Kupffer cells). Eur J Biochem 192:245
7. Dyckerhoff H, Goossens N (1939) Über die thromboseverhütende Wirkung des Neodyms (Neodympräparat "Auer 144"). Z Ges Exp Med 106:181
8. Dyckerhoff H, von Behm W, Goossens N, Miehler H (1936) Über die Gerinnung des Blutes. Biochem Z 288:271
9. Feinstein DI (1982) Diagnosis and management of disseminated intravascular coagulation: the role of heparin therapy. Blood 60:284
10. Fourrier F, Chopin C, Goudemand J, Hendrycx S, Caron S, Rime A, Marey A, Lestavel P (1992) Septic shock, multiple organ failure, and disseminated intravascular coagulation. Chest 101:816
11. Funakoshi T, Furushima K, Shimada H, Kojima S (1992) Anticoagulant action of rare earth metals. Biochem Int 28:113
12. Guidi G (1930) Contributo alia farmacologia delle terre rare; il neodimio. Arch Int Pharmacodyn Ther 37:305
13. Hardaway RM, Husni EA, Geever EF, Noyes HE, Burns JW (1961) Endotoxin shock: a manifestation of intravascular coagulation. Ann Surg 154:791
14. Iimuro Y, Yamamoto M, Kohno H, Itakura J, Jujii H, Matsumoto Y (1994) Blockade of liver macrophages by gadolinium chloride reduces lethality in endotoxemic rats - analysis of mechanisms of lethality in endotoxemia. J Leukoc Biol 55:723
15. Kalter EJ, Daha MR, ten Gate JW, Verhoef J, Bouma BN (1985) Activation and inhibition of Hageman factor-dependent pathways and the complement system in uncomplicated bacteremia or bacterial shock. J Infect Dis 151:1019
16. Kobayashi N, Maekawa T, Takada M, Tanaka H, Gonmori H (1983) Criteria for diagnosis of DIC based on the analysis of clinical and laboratory findings in 345 DIC patients collected by the Research Committee on DIC in Japan. Bibl Haematol 49:265
17. Koudstaal J, Dijkhuis FW, Hardonk MJ (1991) Selective depletion of Kupffer cells after intravenous injection of gadolinium chloride. In: Wisse E, Knook DL, McCuskey RS (eds) Cells of the hepatic sinusoid. Kupffer Cell Foundation, Leiden, p 87
18. Kovacs EJ, Brock B, Varesio L, Young HA (1989) I1-2 induction of I1-1β mRNA expression in monocytes. Regulation by agents that block second messenger pathways. J Immunol 143:3532
19. Leclerc F, Hazelzet J, Jude B, Hofhuis W, Hue V, Marinot A, Van der Voort E (1992) Protein C and S deficiency in severe infectious purpura of children: a collaborative study of 40 cases. Intensive Care Med 18:202
20. Mason JW, Kleeberg U, Dolan P, Colman RW (1970) Plasma kallikrein and Hageman factor in gram-negative bacteremia. Ann Intern Med 73:545
21. Mizgerd JP, Molina RM, Stearns RC, Brain JD, Warner AE (1996) Gadolinium induces macrophage apoptosis. J Leukoc Biol 59:189
22. Mohler KM, Sleath PR, Fitzner JN, Cerrette DP, Alderson M, Derwar SS, Torrance DS, Otten-Evans C, Greenstreet T, Weerawarna K, Kronheim SR, Petersen M, Gerhart M, Kozlosky C, March C, Black RA (1994) Protection against a lethal dose of endotoxin by an inhibitor of tumor necrosis factor processing. Nature 370:218
23. Odegard OR, Lie M, Abildgaard U (1975) Heparin cofactor activity measured with an amidolytic method. Thromb Res 6:287
24. ++ and calmodulin selectively regulate LPS-inducible cytokine mRNA expression in murine peritoneal macrophages. J Immunol 148:538
25. Pearson JM, Brown AP, Schultze AE, Ganey PE, Roth RA (1996) Gadolinium chloride treatment attenuates hepatic platelet accumulation after lipopolysaccharide administration. Shock 5:408
26. Roland CR, Mangino MJ, Flye MW (1993) Lanthanide "blockade" of antigen-presenting cells suppresses lymphocyte proliferation by inducing nitric oxide synthesis. J Surg Res 54:401
27. Rüttinger D, Vollmar B, Wanner GA, Messmer K (1996) In vivo assessment of hepatic alterations following gadolinium chloride-induced Kupffer cell blockade. J Hepatol 25:960
28. Takei Y, Marzi I, Kauffmann FC, Currin RT, Lemasters JJ, Thurman RG (1990) Increase in survival time of liver transplants by protease inhibitors and a calcium channel blocker, nisoldipine. Transplantation 50:14
29. Taylor FB, Chang A, Esmon CT, D'Angelo A, Vigano-D'Angelo S, Blick KE (1987) Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon. J Clin Invest 79:918
30. Taylor FB, Chang A, Ferrel G, Mather T, Catlett R, Blick K, Esmon CT (1991) C4b-binding protein exacerbates the host response to Escherichia coli. Blood 78:357
31. Thijs LG, de Boer JP, de Groot MCM, Hack CE (1993) Coagulation disorders in septic shock. Intensive Care Med 19:S8
32. Van Deventer SJH, Buller HR, ten Gate JW, Aarden LA, Hack CE, Sturk A (1990) Experimental endotoxemia in humans: analysis of cytokine release and coagulation, fibrinolytic and complement pathways. Blood 76:2520
33. Vincke E, Oelkers HA (1937) Zur Pharmakologie der seltenen Erden; Wirkung auf die Blutgerinnung. Arch Exp Pathol Pharmakol 187:594
34. Vollmar B, Rüttinger D, Wanner GA, Leiderer R, Menger MD (1996) Modulation of Kupffer cell activity by gadolinium chloride in endotoxemic rats. Shock 6:434