Sympathetic blockade blunts hypercapnic pulmonary arterial vasocontriction in newborn piglets

European Journal of Cardio-thoracic Surgery

Volumn 13, Issue 3, 1998, Pages 298-305

  Myers, Jeff L ^a   Domkowski, Patrick W ^a   Wang, Yining ^a   Hopkins, Richard A ^a  

^a GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Hypercapnia; Pulmonary hypertension; Pulmonary impedance; Sympathetic nervous system

Indexed keywords

GUANETHIDINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FEMALE; HYPERCAPNIA; LUNG HEMODYNAMICS; LUNG VASCULAR RESISTANCE; LUNG VASOCONSTRICTION; MALE; NEUROMODULATION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PULMONARY HYPERTENSION; SWINE; SYMPATHETIC TONE;

ANIMALS; EVALUATION STUDIES; FEMALE; HEMODYNAMIC PROCESSES; HYPERCAPNIA; HYPERTENSION, PULMONARY; MALE; PULSATILE FLOW; RANDOM ALLOCATION; SWINE; SYMPATHETIC NERVOUS SYSTEM; VASCULAR RESISTANCE; VASOCONSTRICTION;

EID: 0031969113     PISSN: 10107940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1010-7940(98)00007-4     Document Type: Article

References (28)

1. Domkowski P.W., Cockerham J.T., Crescenzo D.G., Kot P.A., Dyer K.L., Wang Y., Messier R.H., Analououei A.R., Wallace A.R., Hopkins R.A. Pulmonary hydraulic impedance responses to hypoxia and hypercapnia in newborn pigs. J Appl Physiol. 77:1994;386-396.
2. 2 on pulmonary input impedance. J Appl Physiol. 38:1975;52-57.
3. Hopkins R.A. The pathophysiology of pulmonary vascular disease associated with congenital cardiac lesions. In: Yin FCP, editor. Ventricular/Vascular Coupling. New York: Springer, 1986:42-78.
4. 2 on pulmonary and systemic hemodynamics after surgery in children with congenital heart disease and pulmonary hypertension. J Pediatr Res. 113:1988;474-479.
5. 2, attenuates hypoxia-induced pulmonary vasoconstriction in newborn lambs. Pediatr Res. 20:1986;113-117.
6. Shirai M., Shindo T., Ninomiya I. β-Adrenergic mechanisms attenuate hypoxic pulmonary vasoconstriction during systemic hypoxia in cats. Am J Physiol (Heart Circ Physiol). 35:1994;H1777-H1785.
7. 2. Chest. 95:1989;773-778.
8. Hales C.A., Westphal D.M. Pulmonary hypoxic vasoconstriction: not affected by chemical sympathectomy. J Appl Physiol. 46(3):1979;529-533.
9. Tucker A. Pulmonary and systemic vascular response to hypoxia after chemical sympathectomy. Cardiovascular Res. 13:1979;469-476.
10. Hung K.S., Hertweck M.S., Hardy J.D. Innervation of the pulmonary alveoli of the mouse lung: an electron microscopic study. Am J Anat. 135:1994;477-496.
11. Milnor W.R., Bergel D.H., Bargainer J.D. Hydraulic power associated with pulmonary blood flow and its relation to heart rate. Circ Res. 19:1966;467-480.
12. Hopkins R.A. Hammon Jr. J.W., McHale P.A., Smith P.K., Anderson R.W. An analysis of the pulsatile hemodynamic responses of the of the pulmonary circulation to acute and chronic pulmonary venous hypertension in the awake dog. Circ Res. 47:1980;902-910.
13. DeBono E.F., Caro C.G. Effect of lung inflating pressure on pulmonary blood pressure and flow. Am J Physiol. 205:1963;1178-1186.
14. Womersley J.R. Oscillatory flow in arteries: the constrained elastic tube as a model of arterial flow and pulse transmission. Phys Med Biol. 2:1957;178-187.
15. 2 after cardiopulmonary bypass. Anesthesiology. 64:1986;311-315.
16. Viitanen A., Salmenpera M., Heinonen J. Right ventricular response to hypercarbia after cardiac surgery. Anesthesiology. 73:1990;393-400.
17. Chang A.C., Zucker H.A., Hickey P.R., Wessel D.L. Pulmonary vascular resistance in infants after cardiac surgery: role of carbon dioxide and hydrogen ion. Crit Care Med. 23:1995;568-574.
18. Hyman A.L., Nandiwada T.H., Knight D.S. Pulmonary vasodilator response to catecholamines and sympathetic nerve stimulation in the cat. Circ Res. 48:1981;407.
19. Lyrene R.K., Welch K.A., Godoy G., Philips III J.B. Alkalosis attenuates hypoxic pulmonary vasoconstriction in neonatal lambs. Pediatr Res. 19:1985;1268-1271.
20. Pace J.B. Sympathetic control of pulmonary vascular impedance in anesthetized dogs. Circ Res. 29:1971;555-568.
21. 2 concentrations on hypoxic pulmonary vasoconstriction. J Appl Physiol. 34(3):1973;318-323.
22. Puybassett L., Stewart T., Rouby J., Cluzel P., Mourgeoun E., Belin M., Arthaud M., Landault C., Viars P. Inhaled nitric oxide reverses the increase in pulmonary vascular resistance induced by permisssive hypercapnia in patients with acute respiratory distress syndrome. Anesthesiology. 80:1994;1254-1267.
23. Shirai M., Kouji S., Ninomiya I. Effects of regional alveolar hypoxia and hypercapnia on small pulmonary vessels in cats. J Appl Physiol. 61(2):1986;440-448.
24. Viles P.H., Shepherd J.T. Evidence for a dilator action of carbon dioxide on the pulmonary vessels of the cat. Circ Res. 22:1968;325-332.
25. Shirai M., Sada K., Ninomiya I. Effects of plasma catecholamines on internal diameter of small pulmonary arteries in the cat. J Physiol Soc Jpn. 47:1986;563-571.
26. Liljestrand G. Chemical control of the distribution of the pulmonary blood flow. Acta Physiol Scand. 44:1958;216-230.
27. Naeije R., Lejeune P., Leeman M., Melot C., Closset J. Pulmonary vascular responses to surgical chemodenervation and chemical sympathectomy in dogs. J Appl Physiol. 66(1):1989;42-50.
28. Rose Jr E.C., Benthuysen K.V., Jackson J.T., Tucker C.E., Kaiser D.L., Grover R.F., Weil J.V. Right ventricular performance during increased afterload impaired by hypercapnic acidosis in conscious dogs. Circ Res. 52:1983;76-84.