메뉴 건너뛰기




Volumn 31, Issue 5, 1998, Pages 773-778

Direct effects of statins on the vascular wall

Author keywords

Cholesterol synthesis; Fluvastatin; HMG CoA reductase inhibitors; Myocyte proliferation; Pravastatin

Indexed keywords

FLUINDOSTATIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; ISOPRENOID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MEVALONIC ACID; PRAVASTATIN; TRIACYLGLYCEROL;

EID: 0031968956     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199805000-00017     Document Type: Article
Times cited : (95)

References (82)
  • 1
    • 0022980592 scopus 로고
    • Serum cholesterol, blood pressure, and mortality: Implications from a cohort of 361,662 men
    • Martin MJ, Hulley SB, Browner WS, Kuller LH, Wentworth D. Serum cholesterol, blood pressure, and mortality: implications from a cohort of 361,662 men. Lancet 1986;2:933-6.
    • (1986) Lancet , vol.2 , pp. 933-936
    • Martin, M.J.1    Hulley, S.B.2    Browner, W.S.3    Kuller, L.H.4    Wentworth, D.5
  • 2
    • 0029813486 scopus 로고    scopus 로고
    • Mortality after 16 years for participants randomized to the Multiple Risk Factor Intervention Trial
    • The Multiple Risk Factor Intervention Trial Research Group. Mortality after 16 years for participants randomized to the Multiple Risk Factor Intervention Trial. Circulation 1996;94:946-51.
    • (1996) Circulation , vol.94 , pp. 946-951
  • 4
    • 0022656719 scopus 로고
    • Patterns of coronary heart disease morbidity and mortality in the sexes: A 26-year follow-up of the Framingham population
    • Lerner DJ, Kannel WB. Patterns of coronary heart disease morbidity and mortality in the sexes: a 26-year follow-up of the Framingham population. Am Heart J 1986;111:383-90.
    • (1986) Am Heart J , vol.111 , pp. 383-390
    • Lerner, D.J.1    Kannel, W.B.2
  • 5
    • 0028154543 scopus 로고
    • Second report of the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II)
    • National Cholesterol Education Program. Second report of the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II). Circulation 1994;89:1333-445.
    • (1994) Circulation , vol.89 , pp. 1333-1445
  • 6
    • 0021349709 scopus 로고
    • The Lipid Research Clinics Coronary Primary Prevention Trial results. II. the relationship of reduction in incidence of coronary heart disease to cholesterol lowering
    • Lipid Research Clinics Program. The Lipid Research Clinics Coronary Primary Prevention Trial results. II. The relationship of reduction in incidence of coronary heart disease to cholesterol lowering. JAMA 1984;251:365-74.
    • (1984) JAMA , vol.251 , pp. 365-374
  • 7
    • 0023232216 scopus 로고
    • Helsinki Heart Study: Primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia: safety of treatment, changes in risk factors, and incidence of coronary heart disease
    • Frick MH, Elo O, Haapa K, et al. Helsinki Heart Study: primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia: safety of treatment, changes in risk factors, and incidence of coronary heart disease. N Engl J Med 1987;317:1237-45.
    • (1987) N Engl J Med , vol.317 , pp. 1237-1245
    • Frick, M.H.1    Elo, O.2    Haapa, K.3
  • 8
    • 0027987849 scopus 로고
    • Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
    • Scandinavian Simvastatin Survival Study Group. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet 1994;344:1383-9.
    • (1994) Lancet , vol.344 , pp. 1383-1389
  • 9
    • 0027322448 scopus 로고
    • Lipid lowering and plaque regression: New insights into prevention of plaque disruption and clinical events in coronary disease
    • Brown BG, Zhao X-Q, Sacco DE, Albers JJ. Lipid lowering and plaque regression: new insights into prevention of plaque disruption and clinical events in coronary disease. Circulation 1993;87:1781-91.
    • (1993) Circulation , vol.87 , pp. 1781-1791
    • Brown, B.G.1    Zhao, X.-Q.2    Sacco, D.E.3    Albers, J.J.4
  • 10
    • 0029050796 scopus 로고
    • Effects of lipid lowering by pravastatin on progression and regression of coronary artery disease in symptomatic men with normal to moderately elevated serum cholesterol levels: The Regression Growth Evaluation Statin Study (REGRESS)
    • Jukema JW, Bruschke AVG, van Boven AJ, et al. Effects of lipid lowering by pravastatin on progression and regression of coronary artery disease in symptomatic men with normal to moderately elevated serum cholesterol levels: the Regression Growth Evaluation Statin Study (REGRESS). Circulation 1995;91:2528-40.
    • (1995) Circulation , vol.91 , pp. 2528-2540
    • Jukema, J.W.1    Bruschke, A.V.G.2    Van Boven, A.J.3
  • 11
    • 0027981582 scopus 로고
    • Effect of simvastatin on coronary atheroma: The Multicentre Anti-Atheroma Study
    • MAAS Investigators. Effect of simvastatin on coronary atheroma: the Multicentre Anti-Atheroma Study. Lancet 1994;344:633-8.
    • (1994) Lancet , vol.344 , pp. 633-638
  • 12
    • 0342981862 scopus 로고    scopus 로고
    • The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels
    • Sacks FM, Pfeffer MA, Moye LA, et al. The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. N Engl J Med 1996;335:1001-9.
    • (1996) N Engl J Med , vol.335 , pp. 1001-1009
    • Sacks, F.M.1    Pfeffer, M.A.2    Moye, L.A.3
  • 13
    • 0028883828 scopus 로고
    • Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia
    • Shepherd J, Cobbe SM, Ford I, et al. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. N Engl J Med 1995;333:1301-7.
    • (1995) N Engl J Med , vol.333 , pp. 1301-1307
    • Shepherd, J.1    Cobbe, S.M.2    Ford, I.3
  • 14
    • 0029069779 scopus 로고
    • Management of primary hyperlipidemia
    • Havel RJ, Rapaport E. Management of primary hyperlipidemia. N Engl J Med 1995;332:1491-8.
    • (1995) N Engl J Med , vol.332 , pp. 1491-1498
    • Havel, R.J.1    Rapaport, E.2
  • 15
    • 0002534379 scopus 로고
    • Drugs used in the treatment of hyperlipoproteinemias
    • Gilman AG, Rail TW, Nies AL, Taylor P, eds. Oxford: Pergamon Press
    • Brown MS, Goldstein JL. Drugs used in the treatment of hyperlipoproteinemias. In: Gilman AG, Rail TW, Nies AL, Taylor P, eds. The pharmacological basis of therapeutics. Oxford: Pergamon Press, 1991:874-96.
    • (1991) The Pharmacological Basis of Therapeutics , pp. 874-896
    • Brown, M.S.1    Goldstein, J.L.2
  • 16
    • 0026448725 scopus 로고
    • The discovery and development of HMG-CoA reductase inhibitors
    • Endo A. The discovery and development of HMG-CoA reductase inhibitors. J Lipid Res 1992;33:1569-82.
    • (1992) J Lipid Res , vol.33 , pp. 1569-1582
    • Endo, A.1
  • 17
    • 0028929401 scopus 로고
    • Pharmacology of competitive inhibitors of HMG-CoA reductase
    • Corsini A, Maggi FM, Catapano AL. Pharmacology of competitive inhibitors of HMG-CoA reductase. Pharmacol Res 1995;31:9-27.
    • (1995) Pharmacol Res , vol.31 , pp. 9-27
    • Corsini, A.1    Maggi, F.M.2    Catapano, A.L.3
  • 18
    • 0018939225 scopus 로고
    • Mevinolin: A highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme a reductase and a cholesterol-lowering agent
    • Alberts AW, Chen J, Kuron G, et al. Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent. Proc Natl Acad Sci U S A 1980;77:3957-61.
    • (1980) Proc Natl Acad Sci U S A , vol.77 , pp. 3957-3961
    • Alberts, A.W.1    Chen, J.2    Kuron, G.3
  • 19
    • 0022485201 scopus 로고
    • CS-514, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme a reductase: Tissue-selective inhibition of sterol synthesis and hypolipidemic effect on various animal species
    • Tsujita Y, Kuroda M, Shimada Y, et al. CS-514, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase: tissue-selective inhibition of sterol synthesis and hypolipidemic effect on various animal species. Biochim Biophys Acta 1986;877:50-60.
    • (1986) Biochim Biophys Acta , vol.877 , pp. 50-60
    • Tsujita, Y.1    Kuroda, M.2    Shimada, Y.3
  • 20
    • 0021997673 scopus 로고
    • 3-Hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors. 1. Structural modifications of 5-substituted 3.5-dihydroxypentanoic acids and their lactone derivatives
    • Stokker GE, Hoffman WF, Alberts AW, et al. 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 1. Structural modifications of 5-substituted 3.5-dihydroxypentanoic acids and their lactone derivatives. J Med Chem 1985;28:347-58.
    • (1985) J Med Chem , vol.28 , pp. 347-358
    • Stokker, G.E.1    Hoffman, W.F.2    Alberts, A.W.3
  • 21
    • 0025794258 scopus 로고
    • HMG-CoA reductase inhibitors: An exciting development in the treatment of hyperlipoproteinemia
    • Kathawala FG. HMG-CoA reductase inhibitors: an exciting development in the treatment of hyperlipoproteinemia. Med Res Rev 1991;11:121-46.
    • (1991) Med Res Rev , vol.11 , pp. 121-146
    • Kathawala, F.G.1
  • 22
    • 0029043903 scopus 로고
    • Reduction of LDL cholesterol by 25% to 60% in patients with primary hypercholesterolemia by atorvastatin, a new HMG-Coa reductase inhibitor
    • Nawrocki JW, Weiss SR, Davidson MH, et al. Reduction of LDL cholesterol by 25% to 60% in patients with primary hypercholesterolemia by atorvastatin, a new HMG-CoA reductase inhibitor. Arterioscler Thromb 1995;15:678-82.
    • (1995) Arterioscler Thromb , vol.15 , pp. 678-682
    • Nawrocki, J.W.1    Weiss, S.R.2    Davidson, M.H.3
  • 23
    • 0026557541 scopus 로고
    • HMG CoA reductase inhibitors
    • Hunninghake DB. HMG CoA reductase inhibitors. Curr Opin Lipidol 1992;3:22-8.
    • (1992) Curr Opin Lipidol , vol.3 , pp. 22-28
    • Hunninghake, D.B.1
  • 24
    • 0028049172 scopus 로고
    • HMG CoA reductase inhibitors
    • Feussner G. HMG CoA reductase inhibitors. Curr Opin Lipidol 1994;5:59-68.
    • (1994) Curr Opin Lipidol , vol.5 , pp. 59-68
    • Feussner, G.1
  • 25
    • 0029960414 scopus 로고    scopus 로고
    • Lipid-lowering therapy for patients with or at risk of coronary artery disease
    • Kjekshus J, Pedersen TR, Tobert JA. Lipid-lowering therapy for patients with or at risk of coronary artery disease. Curr Opin Cardiol 1996;11:418-27.
    • (1996) Curr Opin Cardiol , vol.11 , pp. 418-427
    • Kjekshus, J.1    Pedersen, T.R.2    Tobert, J.A.3
  • 26
    • 0028216631 scopus 로고
    • Branch-point reactions in the biosynthesis of cholesterol, dolichol, ubiquinone and prenylated proteins
    • Grunler J, Ericsson J, Dallner G. Branch-point reactions in the biosynthesis of cholesterol, dolichol, ubiquinone and prenylated proteins. Biochim Biophys Acta 1994;1212:259-77.
    • (1994) Biochim Biophys Acta , vol.1212 , pp. 259-277
    • Grunler, J.1    Ericsson, J.2    Dallner, G.3
  • 27
    • 0025120211 scopus 로고
    • Regulation of the mevalonate pathway
    • Goldstein JL, Brown MS. Regulation of the mevalonate pathway. Nature 1990;343:425-30.
    • (1990) Nature , vol.343 , pp. 425-430
    • Goldstein, J.L.1    Brown, M.S.2
  • 28
    • 0019305204 scopus 로고
    • Relation of cholesterol and mevalonic acid to the cell cycle in smooth muscle and Swiss 3T3 cells stimulated to divide by platelet-derived growth factor
    • Habenicht AJR, Glomset JA, Ross R. Relation of cholesterol and mevalonic acid to the cell cycle in smooth muscle and Swiss 3T3 cells stimulated to divide by platelet-derived growth factor. J Biol Chem 1980;255:5134-40.
    • (1980) J Biol Chem , vol.255 , pp. 5134-5140
    • Habenicht, A.J.R.1    Glomset, J.A.2    Ross, R.3
  • 29
    • 0027738796 scopus 로고
    • Requirement for mevalonate in acetylated LDL induction of cholesterol esterification in macrophages
    • Bernini F, Didoni G, Bonfadini G, Bellosta S, Fumagalli R. Requirement for mevalonate in acetylated LDL induction of cholesterol esterification in macrophages. Atherosclerosis 1993;104:19-26.
    • (1993) Atherosclerosis , vol.104 , pp. 19-26
    • Bernini, F.1    Didoni, G.2    Bonfadini, G.3    Bellosta, S.4    Fumagalli, R.5
  • 30
    • 0022398820 scopus 로고
    • Differentiation of neuroblastoma cells induced by an inhibitor of mevalonate synthesis: Relation of neurite outgrowth and acetylcholinesterase activity to changes in cell proliferation and blocked isoprenoid synthesis
    • Maltese WA, Sheridan KM. Differentiation of neuroblastoma cells induced by an inhibitor of mevalonate synthesis: relation of neurite outgrowth and acetylcholinesterase activity to changes in cell proliferation and blocked isoprenoid synthesis. J Cell Physiol 1985;125:540-58.
    • (1985) J Cell Physiol , vol.125 , pp. 540-558
    • Maltese, W.A.1    Sheridan, K.M.2
  • 31
    • 0027185879 scopus 로고
    • Relationship between mevalonate pathway and arterial myocyte proliferation: In vitro studies with inhibitors of HMG-CoA reductase
    • Corsini A, Mazzotti M, Raiten M, et al. Relationship between mevalonate pathway and arterial myocyte proliferation: in vitro studies with inhibitors of HMG-CoA reductase. Atherosclerosis 1993;101:117-25.
    • (1993) Atherosclerosis , vol.101 , pp. 117-125
    • Corsini, A.1    Mazzotti, M.2    Raiten, M.3
  • 32
    • 0029006319 scopus 로고
    • Pathogenesis of atherosclerosis and the role of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors
    • Corsini A, Raiteri M, Soma MR, Bernini F, Fumagalli R, Paoletti R. Pathogenesis of atherosclerosis and the role of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors. Am J Cardiol 1995;76:21-8A.
    • (1995) Am J Cardiol , vol.76
    • Corsini, A.1    Raiteri, M.2    Soma, M.R.3    Bernini, F.4    Fumagalli, R.5    Paoletti, R.6
  • 33
    • 0029737574 scopus 로고    scopus 로고
    • Non-lipid-related effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors
    • Corsini A, Bernini F, Quarato P, et al. Non-lipid-related effects of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors. Cardialog 1996;87:458-68.
    • (1996) Cardialog , vol.87 , pp. 458-468
    • Corsini, A.1    Bernini, F.2    Quarato, P.3
  • 34
    • 0029825999 scopus 로고    scopus 로고
    • Inhibitor of proliferation of arterial smooth-muscle cells by fluvastatin
    • Corsini A, Pazzucconi F, Pfister P, Paoletti R, Sirtori CR. Inhibitor of proliferation of arterial smooth-muscle cells by fluvastatin [Letter]. Lancet 1996;348:1584.
    • (1996) Lancet , vol.348 , pp. 1584
    • Corsini, A.1    Pazzucconi, F.2    Pfister, P.3    Paoletti, R.4    Sirtori, C.R.5
  • 35
    • 0030058148 scopus 로고    scopus 로고
    • Inhibition of the mevalonate pathway: Benefits beyond cholesterol reduction?
    • Massy ZA, Keane WF, Kasiske BL. Inhibition of the mevalonate pathway: benefits beyond cholesterol reduction? Lancet 1996;347:102-3.
    • (1996) Lancet , vol.347 , pp. 102-103
    • Massy, Z.A.1    Keane, W.F.2    Kasiske, B.L.3
  • 36
    • 0029948598 scopus 로고    scopus 로고
    • Can the clinical efficacy of the HMG CoA reductase inhibitors be explained solely by their effects on LDL-cholesterol?
    • Gaw A. Can the clinical efficacy of the HMG CoA reductase inhibitors be explained solely by their effects on LDL-cholesterol? [Letter]. Atherosclerosis 1996;125:267-9.
    • (1996) Atherosclerosis , vol.125 , pp. 267-269
    • Gaw, A.1
  • 37
    • 0027241856 scopus 로고
    • The pathogenesis of atherosclerosis: A perspective for the 1990s
    • Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 1993;362:801-9.
    • (1993) Nature , vol.362 , pp. 801-809
    • Ross, R.1
  • 38
    • 0025950107 scopus 로고
    • Update on the pathogenesis of atherosclerosis
    • Wissler RW. Update on the pathogenesis of atherosclerosis. Am J Med 1991;91:3-9S.
    • (1991) Am J Med , vol.91
    • Wissler, R.W.1
  • 39
    • 0025281462 scopus 로고
    • Syndromes of accelerated atherosclerosis: Role of vascular injury and smooth muscle cell proliferation
    • Ip JH, Fuster V, Badimon L, Badimon J, Taubman MB, Chesebro JH. Syndromes of accelerated atherosclerosis: role of vascular injury and smooth muscle cell proliferation. J Am Coll Cardiol 1990;15:1667-87.
    • (1990) J am Coll Cardiol , vol.15 , pp. 1667-1687
    • Ip, J.H.1    Fuster, V.2    Badimon, L.3    Badimon, J.4    Taubman, M.B.5    Chesebro, J.H.6
  • 40
    • 0027513267 scopus 로고
    • Frequency and consequences of intimal hyperplasia in specimens retrieved by directional atherectomy of native primary coronary artery stenoses and subsequent restenoses
    • Miller MJ, Kuntz RE, Friedrich SP, et al. Frequency and consequences of intimal hyperplasia in specimens retrieved by directional atherectomy of native primary coronary artery stenoses and subsequent restenoses. Am J Cardiol 1993;71:652-8.
    • (1993) Am J Cardiol , vol.71 , pp. 652-658
    • Miller, M.J.1    Kuntz, R.E.2    Friedrich, S.P.3
  • 41
    • 0027932378 scopus 로고
    • Use of human tissue specimens obtained by directional atherectomy to study restenosis
    • Isner JM, Kearney M, Bauters C, et al. Use of human tissue specimens obtained by directional atherectomy to study restenosis. Trends Cardiovasc Med 1994;4:213-21.
    • (1994) Trends Cardiovasc Med , vol.4 , pp. 213-221
    • Isner, J.M.1    Kearney, M.2    Bauters, C.3
  • 42
    • 0027179403 scopus 로고
    • Proliferation in primary and restenotic coronary atherectomy tissue: Implications for antiproliferative therapy
    • O'Brien ER, Alpers CE, Stewart DK, et al. Proliferation in primary and restenotic coronary atherectomy tissue: implications for antiproliferative therapy. Circ Res 1993;73:223-31.
    • (1993) Circ Res , vol.73 , pp. 223-231
    • O'Brien, E.R.1    Alpers, C.E.2    Stewart, D.K.3
  • 43
    • 0027740243 scopus 로고
    • Human atherosclerosis. IV. Immunocytochemical analysis of cell activation and proliferation in lesions of young adults
    • Katsuda S, Coltrera MD, Ross R, Gown AM. Human atherosclerosis. IV. Immunocytochemical analysis of cell activation and proliferation in lesions of young adults. Am J Pathol 1993;142:1787-93.
    • (1993) Am J Pathol , vol.142 , pp. 1787-1793
    • Katsuda, S.1    Coltrera, M.D.2    Ross, R.3    Gown, A.M.4
  • 44
    • 0027157897 scopus 로고
    • Proliferative activity in peripheral and coronary atherosclerotic plaque among patients undergoing percutaneous revascularization
    • Pickering JG, Weir L, Jekanowski J, Kearney MA, Isner JM. Proliferative activity in peripheral and coronary atherosclerotic plaque among patients undergoing percutaneous revascularization. J Clin Invest 1993;91:1469-80.
    • (1993) J Clin Invest , vol.91 , pp. 1469-1480
    • Pickering, J.G.1    Weir, L.2    Jekanowski, J.3    Kearney, M.A.4    Isner, J.M.5
  • 46
    • 0026495734 scopus 로고
    • Pharmacology of smooth muscle cell replication
    • Jackson CL, Schwartz SM. Pharmacology of smooth muscle cell replication. Hypertension 1992;20:713-36.
    • (1992) Hypertension , vol.20 , pp. 713-736
    • Jackson, C.L.1    Schwartz, S.M.2
  • 47
    • 0028170814 scopus 로고
    • Role of protein modification reactions in programming interactions between ras-related GTPases and cell membranes
    • Glomset JA, Farnsworth CC. Role of protein modification reactions in programming interactions between ras-related GTPases and cell membranes. Annu Rev Cell Biol 1994;10:181-205.
    • (1994) Annu Rev Cell Biol , vol.10 , pp. 181-205
    • Glomset, J.A.1    Farnsworth, C.C.2
  • 48
    • 0028947890 scopus 로고
    • In vivo enhanced antitumor activity of carmustine [N,N′-bis(2-chloroethyl)-N-nitrosourea] by simvastatin
    • Soma MR, Baetta R, De Renzis MR, et al. In vivo enhanced antitumor activity of carmustine [N,N′-bis(2-chloroethyl)-N-nitrosourea] by simvastatin. Cancer Res 1995;55:597-602.
    • (1995) Cancer Res , vol.55 , pp. 597-602
    • Soma, M.R.1    Baetta, R.2    De Renzis, M.R.3
  • 49
    • 0027537289 scopus 로고
    • HMG CoA reductase inhibitors: In vivo effects on carotid intimal thickening in normocholesterolemic rabbits
    • Soma MR, Donetti E, Parolini C, et al. HMG CoA reductase inhibitors: in vivo effects on carotid intimal thickening in normocholesterolemic rabbits. Arterioscler Thromb 1993;13:571-8.
    • (1993) Arterioscler Thromb , vol.13 , pp. 571-578
    • Soma, M.R.1    Donetti, E.2    Parolini, C.3
  • 50
    • 0026081431 scopus 로고
    • Simvastatin but not pravastatin inhibits the proliferation of rat aorta myocytes
    • Corsini A, Raiteri M, Soma M, Fumagalli R, Paoletti R. Simvastatin but not pravastatin inhibits the proliferation of rat aorta myocytes. Pharmacol Res 1991;23:173-80.
    • (1991) Pharmacol Res , vol.23 , pp. 173-180
    • Corsini, A.1    Raiteri, M.2    Soma, M.3    Fumagalli, R.4    Paoletti, R.5
  • 51
    • 0029902939 scopus 로고    scopus 로고
    • Human and porcine smooth muscle cells share similar proliferation dependence on the mevalonate pathway: Implication for in vivo interventions in the porcine model
    • Martinet-Gonzalez J, Badimon L. Human and porcine smooth muscle cells share similar proliferation dependence on the mevalonate pathway: implication for in vivo interventions in the porcine model. Eur J Clin Invest 1996;26:1023-32.
    • (1996) Eur J Clin Invest , vol.26 , pp. 1023-1032
    • Martinet-Gonzalez, J.1    Badimon, L.2
  • 52
    • 0030574249 scopus 로고    scopus 로고
    • Inhibitory effect of fluvastatin at doses insufficient to lower serum lipids on the catheter-induced thickening of intima in rabbit femoral artery
    • Bandoh T, Mitani H, Niihashi M, et al. Inhibitory effect of fluvastatin at doses insufficient to lower serum lipids on the catheter-induced thickening of intima in rabbit femoral artery. Eur J Pharmacol 1996;315:37-42.
    • (1996) Eur J Pharmacol , vol.315 , pp. 37-42
    • Bandoh, T.1    Mitani, H.2    Niihashi, M.3
  • 53
    • 0029796276 scopus 로고    scopus 로고
    • The role of isoprenoids in vascular smooth muscle: Potential benefits of statins unrelated to cholesterol lowering
    • Hughes AD. The role of isoprenoids in vascular smooth muscle: potential benefits of statins unrelated to cholesterol lowering. J Hum Hypertens 1996;10:387-90.
    • (1996) J Hum Hypertens , vol.10 , pp. 387-390
    • Hughes, A.D.1
  • 54
    • 0026694388 scopus 로고
    • Pharmacokinetics of fluvastatin after single and multiple doses in normal volunteers
    • Tse FLS, Jaffe JM, Troendle A. Pharmacokinetics of fluvastatin after single and multiple doses in normal volunteers. J Clin Pharmacol 1992;32:630-8.
    • (1992) J Clin Pharmacol , vol.32 , pp. 630-638
    • Fls, T.1    Jaffe, J.M.2    Troendle, A.3
  • 58
    • 0026814425 scopus 로고
    • Comparative pharmacokinetics of lovastatin, simvastatin and pravastatin in humans
    • Pentikainen PJ, Saraheimo M, Schwartz JI, et al. Comparative pharmacokinetics of lovastatin, simvastatin and pravastatin in humans. J Clin Pharmacol 1992;32:136-40.
    • (1992) J Clin Pharmacol , vol.32 , pp. 136-140
    • Pentikainen, P.J.1    Saraheimo, M.2    Schwartz, J.I.3
  • 59
    • 0026436279 scopus 로고
    • The prenylation of proteins
    • Sinensky M, Lutz RJ. The prenylation of proteins. Bioessays 1992;14:25-31.
    • (1992) Bioessays , vol.14 , pp. 25-31
    • Sinensky, M.1    Lutz, R.J.2
  • 60
    • 0029898894 scopus 로고    scopus 로고
    • Protein prenylation: Molecular mechanisms and functional consequences
    • Zhang FL, Casey PJ. Protein prenylation: molecular mechanisms and functional consequences. Annu Rev Biochem 1996;65:241-69.
    • (1996) Annu Rev Biochem , vol.65 , pp. 241-269
    • Zhang, F.L.1    Casey, P.J.2
  • 65
    • 0029620353 scopus 로고
    • Inhibition of isoprenoid biosynthesis and arterial smooth-muscle cell proliferation
    • Soma MR, Parolini C, Donetti E, Fumagalli R, Paoletti R. Inhibition of isoprenoid biosynthesis and arterial smooth-muscle cell proliferation. J Cardiovasc Pharmacol 1995:25(suppl 4):S20-S4.
    • (1995) J Cardiovasc Pharmacol , vol.25 , Issue.4 SUPPL.
    • Soma, M.R.1    Parolini, C.2    Donetti, E.3    Fumagalli, R.4    Paoletti, R.5
  • 66
    • 0026591167 scopus 로고
    • Carrier-mediated uptake of pravastatin by rat hepatocytes in primary culture
    • Komai T, Shigehara E, Tokui T, et al. Carrier-mediated uptake of pravastatin by rat hepatocytes in primary culture. Biochem Pharmacol 1992;43:667-70.
    • (1992) Biochem Pharmacol , vol.43 , pp. 667-670
    • Komai, T.1    Shigehara, E.2    Tokui, T.3
  • 67
    • 0022413876 scopus 로고
    • Suppression of murine neuroblastoma growth in vivo by mevinolin, a competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme a reductase
    • Maltese WA, Defendini R, Green RA, Sheridan KM, Donley DK. Suppression of murine neuroblastoma growth in vivo by mevinolin, a competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. J Clin Invest 1985;76:1748-54.
    • (1985) J Clin Invest , vol.76 , pp. 1748-1754
    • Maltese, W.A.1    Defendini, R.2    Green, R.A.3    Sheridan, K.M.4    Donley, D.K.5
  • 68
    • 0025963033 scopus 로고
    • Effect of lovastatin on intimal hyperplasia after balloon angioplasty: A study in an atherosclerotic hypercholesterolemic rabbit
    • Gellman J, Ezekowtiz MD, Sarembock IJ, et al. Effect of lovastatin on intimal hyperplasia after balloon angioplasty: a study in an atherosclerotic hypercholesterolemic rabbit. J Am Coll Cardiol 1991;17:251-9.
    • (1991) J am Coll Cardiol , vol.17 , pp. 251-259
    • Gellman, J.1    Ezekowtiz, M.D.2    Sarembock, I.J.3
  • 69
  • 70
    • 0027995418 scopus 로고
    • Antiatherosclerotic activity of inhibitors of 3-hydroxy-3-methylglutaryl coenzyme a reductase in cholesterol-fed rabbits: A biochemical and morphological evaluation
    • Bocan TMA, Mazur MJ, Mueller SB, et al. Antiatherosclerotic activity of inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase in cholesterol-fed rabbits: a biochemical and morphological evaluation. Atherosclerosis 1994;111:127-42.
    • (1994) Atherosclerosis , vol.111 , pp. 127-142
    • Bocan, T.M.A.1    Mazur, M.J.2    Mueller, S.B.3
  • 71
    • 0026071965 scopus 로고
    • Treatment with hydroxymethylglutaryl-coenzyme a reductase inhibitors in hypercholesterolemia induces changes in the components of the extrinsic coagulation system
    • Sandset PM, Lund H, Norseth J, Abildgaard U, Ose L. Treatment with hydroxymethylglutaryl-coenzyme A reductase inhibitors in hypercholesterolemia induces changes in the components of the extrinsic coagulation system. Arterioscler Thromb 1991;11:138-45.
    • (1991) Arterioscler Thromb , vol.11 , pp. 138-145
    • Sandset, P.M.1    Lund, H.2    Norseth, J.3    Abildgaard, U.4    Ose, L.5
  • 72
    • 0027251606 scopus 로고
    • Decreased in vitro oxidizability of low-density lipoprotein in hypercholesterolaemic patients treated with 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors
    • Kleinveld HA, Demacker PNM, De Haan AFJ, Stalenhoef AFH. Decreased in vitro oxidizability of low-density lipoprotein in hypercholesterolaemic patients treated with 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors. Eur J Clin Invest 1993;23:289-95.
    • (1993) Eur J Clin Invest , vol.23 , pp. 289-295
    • Kleinveld, H.A.1    Demacker, P.N.M.2    De Haan, A.F.J.3    Stalenhoef, A.F.H.4
  • 73
    • 0026589912 scopus 로고
    • Lovastatin inhibits low-density lipoprotein oxidation and alters its fluidity and uptake by macrophages: In vitro and in vivo studies
    • Aviram M, Dankner G, Cogan U, Hochgraf E, Brook JG. Lovastatin inhibits low-density lipoprotein oxidation and alters its fluidity and uptake by macrophages: in vitro and in vivo studies. Metabolism 1992;41:229-35.
    • (1992) Metabolism , vol.41 , pp. 229-235
    • Aviram, M.1    Dankner, G.2    Cogan, U.3    Hochgraf, E.4    Brook, J.G.5
  • 74
    • 0031050342 scopus 로고    scopus 로고
    • Reduced susceptibility of low-density lipoprotein (LDL) to lipid peroxidation after fluvastatin therapy is associated with the hypocholesterolemic effect of the drug and its binding to the LDL
    • Hussein O, Schlezinger S, Rosenblat M, Keidar S, Aviram M. Reduced susceptibility of low-density lipoprotein (LDL) to lipid peroxidation after fluvastatin therapy is associated with the hypocholesterolemic effect of the drug and its binding to the LDL. Atherosclerosis 1997;128:11-8.
    • (1997) Atherosclerosis , vol.128 , pp. 11-18
    • Hussein, O.1    Schlezinger, S.2    Rosenblat, M.3    Keidar, S.4    Aviram, M.5
  • 75
    • 0029119711 scopus 로고
    • Effect of pravastatin on outcomes after cardiac transplantation
    • Kobashigawa JA, Katznelson S, Laks H, et al. Effect of pravastatin on outcomes after cardiac transplantation. N Engl J Med 1995;333:621-7.
    • (1995) N Engl J Med , vol.333 , pp. 621-627
    • Kobashigawa, J.A.1    Katznelson, S.2    Laks, H.3
  • 76
    • 0029116986 scopus 로고
    • HMG-CoA reductase inhibitors reduce acetyl LDL endocytosis in mouse peritoneal macrophages
    • Bernini F, Scurati N, Bonfadini G, Fumagalli R. HMG-CoA reductase inhibitors reduce acetyl LDL endocytosis in mouse peritoneal macrophages. Arterioscler Thromb 1995;15:1352-8.
    • (1995) Arterioscler Thromb , vol.15 , pp. 1352-1358
    • Bernini, F.1    Scurati, N.2    Bonfadini, G.3    Fumagalli, R.4
  • 77
    • 0030592542 scopus 로고    scopus 로고
    • Lovastatin inhibits gene expression of type-I scavenger receptor in THP-1 human macrophages
    • Umetani N, Kanayama Y, Okamura M, Negoro N, Takeda T. Lovastatin inhibits gene expression of type-I scavenger receptor in THP-1 human macrophages. Biochim Biophys Acta 1996;1303:199-206.
    • (1996) Biochim Biophys Acta , vol.1303 , pp. 199-206
    • Umetani, N.1    Kanayama, Y.2    Okamura, M.3    Negoro, N.4    Takeda, T.5
  • 78
    • 0021359767 scopus 로고
    • Inhibition of cholesterol synthesis reduces low-density-lipoprotein apoprotein B production without decreasing very-low-density-lipoprotein apoprotein B synthesis in rabbits
    • La Ville A, Moshy R, Turner PR, Miller NE, Lewis B. Inhibition of cholesterol synthesis reduces low-density-lipoprotein apoprotein B production without decreasing very-low-density-lipoprotein apoprotein B synthesis in rabbits. Biochem J 1984;219:321-3.
    • (1984) Biochem J , vol.219 , pp. 321-323
    • La Ville, A.1    Moshy, R.2    Turner, P.R.3    Miller, N.E.4    Lewis, B.5
  • 79
    • 0027492038 scopus 로고
    • Simvastatin inhibits the oxidation of low-density lipoproteins by activated human monocyte-derived macrophages
    • Giroux LM, Davignon J, Naruszewicz M. Simvastatin inhibits the oxidation of low-density lipoproteins by activated human monocyte-derived macrophages. Biochim Biophys Acta 1993;1165:335-8.
    • (1993) Biochim Biophys Acta , vol.1165 , pp. 335-338
    • Giroux, L.M.1    Davignon, J.2    Naruszewicz, M.3
  • 80
    • 0029004377 scopus 로고
    • Baseline serum cholesterol and treatment effect in the Scandinavian Simvastatin Survival Study (4S)
    • Scandinavian Simvastatin Survival Study Group. Baseline serum cholesterol and treatment effect in the Scandinavian Simvastatin Survival Study (4S). Lancet 1995;345:1274-5.
    • (1995) Lancet , vol.345 , pp. 1274-1275
  • 81
    • 0030841001 scopus 로고    scopus 로고
    • Effects of fluvastatin on coronary atherosclerosis in patients with mild to moderate cholesterol elevations [Lipoprotein and Coronary Atherosclerosis Study (LCAS)]
    • Herd JA, Ballantyne CM, Farmer JA, et al. Effects of fluvastatin on coronary atherosclerosis in patients with mild to moderate cholesterol elevations [Lipoprotein and Coronary Atherosclerosis Study (LCAS)]. Am J Cardiol 1997;80:278-86.
    • (1997) Am J Cardiol , vol.80 , pp. 278-286
    • Herd, J.A.1    Ballantyne, C.M.2    Farmer, J.A.3
  • 82
    • 0028285804 scopus 로고
    • Prevention of restenosis after coronary balloon angioplasty: Rationale and design of the Fluvastatin Angioplasty Restenosis (FLARE) Trial
    • Foley DP, Bonnier H, Jackson G, et al. Prevention of restenosis after coronary balloon angioplasty: rationale and design of the Fluvastatin Angioplasty Restenosis (FLARE) Trial. Am J Cardiol 1994;73:50-61D.
    • (1994) Am J Cardiol , vol.73
    • Foley, D.P.1    Bonnier, H.2    Jackson, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.