Adhesion molecules and microvascular changes in the nonobese diabetic (NOD) mouse pancreas. An NO-inhibitor (L-Name) is unable to block adhesion inflammation-induced activation

Autoimmunity

Volumn 27, Issue 2, 1998, Pages 65-77

  Papaccio, Gianpaolo ^a,d   Latronico, Michael V G ^a   Pisanti, Francesco Aurelio ^b   Federlin, Konrad ^c   Linn, Thomas ^c  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

^b ASL NA4 Brusciano   (Italy)

^c JUSTUS LIEBIG UNIVERSITY   (Germany)

^d NONE   (Italy)

Author keywords

Adhesion molecules; Endothelium; NAME; NOD mice; Pancreatic islets

Indexed keywords

ARGININE METHYL ESTER; CELL ADHESION MOLECULE; INTERCELLULAR ADHESION MOLECULE 1;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; IMMUNOREACTIVITY; INFLAMMATION; MALE; MICROVASCULATURE; MOUSE; NONHUMAN; PANCREAS;

EID: 0031968770     PISSN: 08916934     EISSN: None     Source Type: Journal    
DOI: 10.3109/08916939809008037     Document Type: Article

References (35)

1. Papaccio, G., Linn, T., Federlin, K., Volkman, A., Esposito, V. and Mezzogiorno, V. (1991). Further morphological and biochemical observations on early low dose streptozocin diabetes in mice. Pancreas, 6, 659-667.
2. Papaccio, G., Linn, T. and Chieffi Baccari, G. (1993). Morphological observations on pancreatic islet blood vessels in low-dose streptozocin-treated mice. J Anat, 182, 45-53.
3. Papaccio, G. and Chieffi Baccari, G. (1992). Alterations of islet microvasculature in mice treated with low dose streptozocin. Histochemistry, 97, 371-374.
4. Majno, G., Joris, I. I., Handler, E. S., Desemone, J., Mordes, J. P. and Rossini, A. A. (1987). A pancreatic venular defect in the BB/Wor rat. Am J Pathol, 128, 210-215.
5. Sandler, S. and Jansson, L. (1985). Vascular permeability of pancreatic islets after administration of streptozocin. Virchows Arch (A), 407, 359-367.
6. Beppu, H., Maruta, K., Kurner, T. and Kolb, H. (1987). Diabetogenic action of streptozocin: essential role of membrane permeability. Acta Endocrinol., 114, 90-95.
7. Papaccio, G., Chieffi Baccari, G., Mezzogiorno, V. and Esposito, V. (1993). Extraislet infiltration in NOD mouse pancreas: observations after immunomodulation. Pancreas, 8, 459-464.
8. Pozzilli, P., Cartenuto, P. and Delitala. (1994). Lymphocyte traffic and homing into target tissue and the generation of endocrine autoimmunity. Clin Endocrinol, 41, 545-554.
9. Hänninen, A., Jalkanen, S., Salmi, M., Toikkanen, S., Nikolakros, G. and Simell, O. (1992). Macrophages, T-cell receptor usage and endothelial cell activation in the pancreas at the onset of insulin-dependent diabetes mellitus. J Clin Invest, 90, 1901-1910.
10. Hänninen, A., Salmi, M., Simell, O. and Jalkanen,S. (1993). Endothelial cell-binding properties of lymphocytes infiltrated into human diabetic pancreas. Implications for pathogenesis of IDDM. Diabetes, 42, 1656-1662.
11. Kanagawa, K., Ishikura, H., Takahashi, C., Tamatani, T., Miyasaka, M., Togashi, M., et al. (1991). Identification of ICAM-1 positive cells in the nongrafted and transplanted rat kidney: an immunohistochemical and ultrastructural study. Transplantation, 52, 1057-1062.
12. Yagi, N., Yokono, K., Nagata, M., Tsukamoto, K., Hasegawa, Y. and Yoneda, R., et al. (1995). Expression of intercellular adhesion molecule 1 on pancreatic β cells accelerates β cell destruction by cytotoxic T-cells in murine autoimmune diabetes. Diabetes, 44, 744-752.
13. Krönke, K.-D., Kolb-Bachofen, V., Berschick, B., Burkart, V. and Kolb, H. (1991). Activated macrophages kill pancreatic syngenic islet cells via arginine-dependent nitric oxide generation. Biochem Biophys Res Commun. 175, 752-758.
14. Krönke, K.-D., Rodriguez, M.-L., Kolb, H. and Kolb-Bachofen, V. (1993). Cytotoxicity of activated rat macrophages against syngeneic islet cells is arginine-dependent, correlates with citrulline and nitrite concentrations and is identical to lysis by the nitric oxide donor nitroprusside. Diabetologia, 36, 17-24.
15. Corbett, J. A., Sweetland, M. A., Wang, J. L., Lancaster Jr., J. R. and McDaniel, M. L. (1993). Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans. Proc Natl Acad Sci USA, 90, 1731-1735.
16. Kolb, H., Kiesel, U., Krönke, K.-D. and Kolb-Bachofen, V. (1991). Suppression of low dose streptozocin induced diabetes in mice by administration of nitric oxide synthase inhibitor. Life Sci, 49, 213-217.
17. Papaccio, G., Esposito, V., Latronico, M. V. G. and Pisanti, F. A. (1995). Administration of a nitric oxide inhibitor does not suppress low-dose streptozocin-treated diabetes in mice. Int J Pancr, 17, 63-68.
18. Welsh, N., Eizirik, D. L. and Sandler, S. (1994). Nitric oxide and pancreatic β-cell destruction in insulin dependent diabetes mellitus: don't take NO for an answer. Antoimmunity, 18, 285-290.
19. L-aginine on the onset of diabetes in spontaneously diabetic BB rat. Diabetologia, 44, 360-364.
20. Sandler, S., Andersson, A. and Hellerström, C. (1987). Inhibitory effects of interleukin-1 on insulin secretion, insulin biosynthesis and oxidative metabolism of isolated rat pancreatic islets. Endocrinology, 121, 1424-1431.
21. 15N] nitrate in biological fluids. Anal Biochem, 126, 131-138.
22. Sternesjö, J., Bendtzen, K. and Sandler, S. (1995). Effects of prolonged exposure in vitro to interferon-γ and tumour necrosis factor-α on nitric oxide and insulin production of rat pancreatic islets. Autoimmunity, 20, 185-190.
23. Bluacerraf, B. and Germain, R. N. (1987). The immune genes of the major histocompatibility complex, Immunol Rev, 38, 70-119.
24. Springer, T. A. (1990). Adhesion receptors of the immune system. Nature, 346, 425-434.
25. Linn, T., Strate. C., Federlin, K. and Papaccio, G. (1994). Inter-cellular-adhesion-molecule-1 (ICAM-1) expression in the islets of nonobese diabetic (NOD) and low-dose streptozocin-treated mouse pancreas. Histochemistry, 94, 371-374.
26. Pober, J. S. and Cotran, R. S. (1990). The role of endothelial cells in inflammation. Transplantation, 50, 537-544.
27. Holstad, M. and Sandler, S. (1993). Aminoguanidine, an inhibitor of NO formation, fails to protect against insulitis and hyperglycaemia induced by multiple low dose streptozocin injections in mice. Autoimmunity, 15, 311-314.
28. Voorbij, H. A. M., Jeucken, P. H. M., Kabel, P. J., De Haan, M. and Drexhage, H. A. (1989). Dendritic cells and scavenger macrophages in pancreatic islets of prediabetic BB rats. Diabetes, 38, 1623-1629.
29. Jansen, A., Voorbij, H. A. M., Jeucken, P. H. M., Bruining, G. J., Hooijkaas, H. and Drexhage, H. A. (1993). An immunohistochemical study on organized lymphoid cell infiltrates in fetal and neonatal pancreases. A comparison with similar infiltrates found in the pancreas of a diabetic infant. Autoimmunity, 15, 31-38.
30. Yang, X.-D., Michie, S. A., Mebius, R. E., Tisch, R., Weissman, I. and McDevitt, H. O. (1996). The role of cell adhesion molecules in the development of IDDM. Implications for pathogenesis and therapy. Diabetes, 45, 705-710.
31. Bonner-Weir, S. and Orci, L. (1982). New perspectives on the microvasculature of the islets of Langerhans in the rat. Diabetes, 31, 883-889.
32. Osborn, L. (1990). Leukocyte adhesion to endothelium inflammation. Cell, 62, 3-6.
33. Papaccio, G. (1993). Insulitis and islet microvasculature in type 1 diabetes, (invited review) Histol Histopathol, 8, 751-759.
34. Butcher, E. C., Lewinsohn, D., Duijvestijn, A., Bargatze, R., Wu, N. and Jalkanen, S. (1986). Interactions between endothelial cells and leukocytes. J Cell Biochem, 30, 121-133.
35. Papaccio, G., Chieffi Baccari, G., Strate, C. and Linn, T. (1994). Pancreatic duct infiltration in the nonobese diabetic (NOD) mouse. J Anat, 185, 465-470.