Role of HLA antigens in liver transplantation with special reference to cellular immune reactions

Langenbeck's Archives of Surgery

Volumn 383, Issue 1, 1998, Pages 87-94

  Markus, Bernd H ^a   Duquesnoy, Rene J ^b   Blaheta, Roman A ^a   Scholz, Martin ^a   Encke, Albrecht ^a  

^a GOETHE UNIVERSITY   (Germany)

^b UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

Hepatitis; HLA; HLA restriction; Liver transplantation

Indexed keywords

HLA ANTIGEN;

ALLOIMMUNITY; ANTIBODY RESPONSE; ARTICLE; GRAFT REJECTION; HEPATITIS; HISTOCOMPATIBILITY; HISTOPATHOLOGY; HLA SYSTEM; HUMAN; LIVER TRANSPLANTATION; LYMPHOCYTIC INFILTRATION; NONHUMAN; PRIORITY JOURNAL; SURVIVAL; T LYMPHOCYTE;

CELLS, CULTURED; GRAFT REJECTION; HEPATITIS B; HEPATITIS C; HLA ANTIGENS; HUMANS; IMMUNITY, CELLULAR; LIVER TRANSPLANTATION; RECURRENCE;

EID: 0031968746     PISSN: 14352443     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004230050097     Document Type: Article

References (76)

1. Gordon RD, Fung JJ, Markus BH, Fox I, Iwatsuki S, Esquivel CO, Tzakis AG, Todo S, Scarzl TE (1986) The antibody crossmatch in liver transplantation. Surgery 100:705-715
2. Fung JJ, Griffin M, Duquesnoy R, Shaw BW, Starzl TE (1987) Successful sequential liver-kidney transplantation in a patient with preformed lymphocytotoxic antibodies. Transplant Proc 19:767-768
3. Gubernatis G, Lauchart W, Jonker M, Steinhoff G, Bornscheuer A, Neuhaus P, van Es AA, Kemnitz J, Wonigeit K, Pichlmayr R (1987) Signs of hyperacute rejection of liver grafts in rhesus monkeys after donor-specific presensitization. Transplant Proc 19:1082-1083
4. Wight DGD (1983) Pathology of liver transplantation (other than rejection) In: Calne RY (ed) Liver transplantation: the Cambridge/Kings College Experience. Grune and Stratton, New York, pp 289-316
5. Steinhoff G, Wonigeit K, Pichlmayr R (1988) Analysis of sequential changes in major histocompatibility complex expression in human liver grafts after transplantation. Transplantation 45:394-401
6. Markus BH, Colson YL, Fung JJ, Zeevi A, Duquesnoy RJ (1988) HLA antigen expression on cultured human arterial endothelial cells. Tissue Antigens 32:241-253
7. Auth MKH, Keitzer R, Scholz M, Blaheta RA, Hottenrott EC, Herrmann G, Encke A, Markus BH (1993) Establishment and immunological characterization of cultured human gallbladder epithelial cells. Hepatology 18:546-555
8. Schroder A, Blaheta RA, Scholz M, Kronenberger B, Encke A, Markus BH (1995) Effects of proinflammatory cytokines on cultivated primary human hepatocytes. Transplantation 59: 1023-1028
9. Demetris AJ, Markus BH (1989) Immunopathology of liver transplantation. CRC Crit Rev Immunol 9:67-92
10. Colson YL, Markus BH, Zeevi A, Duquesnoy RJ (1990) Increased lymphocyte adherence to human arterial endothelial cell nionolayers in the context of allorecosnition. J Immunol 144:2975-2984
11. Saidman S, Duquesnoy RJ, Zeevi A, Fung JJ, Starzl TE, Demetris AJ (1991) Recognition of major histocompatibility complex antigens on cultured human biliary epithelial cells by alloreactive lymphocytes. Hepatology 13:239-246
12. Manez R, White LT, Linden P, Kusne S, Martin M, Kramer D, Demetris AJ, Van Thiel DH, Starzl TE, Duquesnoy RJ (1993) The influence of HLA matching on cytomegalovirus hepatitis and chronic rejection after liver transplantation. Transplantation 55:1067-1071
13. Stratta RJ, Shaeffer MS, Markin RS, Wood RP, Langnas AN, Reed EC, Donovan JP, Woods GL, Bradshaw KA, Pillen TJ, Shaw BW (1992) Cytomegalovirus infection and disease after liver transplantation: an overview. Dig Dis Sci 5:673-688
14. Scholz M, Blaheta RA, Hamann A, Encke A, Markus BH (1992) Infection of human vascular endothelial cells with cytomegalovirus: effects on the expression of human leukocyte antigens. Transplant Proc 24:2565-2566
15. Scholz M, Hamann A, Blaheta RA, Auth MKH, Encke A, Markus BH (1992) Cytomegalovirus- and interferon-related effects on human endothelial cells: cytomegalovirus infection reduces upregulation of HLA class II-antigen expression after treatment with interferon-gamma. Hum Immunol 35:230-238
16. Scholz M, Keitzer RA, Blaheta RA, Auth MKH, Goekce Y, Encke A, Markus BH (1993) Immunological properties of human gallbladder derived epithelial cells: flowcytometric analysis of human leukocyte antigens and adhesion molecule ICAM-1. Tissue Antigens 42:539-543
17. Scholz M, Blaheta RA, Görlich C, Hamann A, Oltrogge J, Harbich E, Martin I, Markus BH (1994) Investigations on cellular infection with human cytomegalovirus in vitro: activation and suppression of the cellular immune response. Z Tx Med 6:72-79
18. Scholz M (1994) Induktion und Modulation von HLA-Antigenen der Klasse I und II auf humanen Endoihelzellen. Thesis, University of Frankfurt
19. Fung JJ, Zeevi A, Starzl TE, Demetris J, Iwatsuki S, Duquesnoy RJ (1986) Functional characterization of infiltrating T lymphocytes in human hepatic allografts. Hum Immunol 16:182-199
20. Fung JJ, Zeevi A, Markus B, Zerbe TR, Duquesnoy RJ (1986) Dynamics of allospecific T lymphocyte infiltration in vascularized human allografts. Immunol Res 5:149-163
21. Markus BH, Fung JJ, Zeevi A, Starzl TE, Demetris AJ, Duquesnoy RJ (1987) Analysis of T lymphocytes infiltrating human hepatic allografts. Transplant Proc 19:2470-2473
22. Daar AS, Fuggle SV, Fabre JW, Ting A, Morris PJ (1984) The detailed distribution of HLA-A, B, C, antigens in normal human organs. Transplantation 38:287-292
23. Daar AS, Fuggle SV, Fabre JW, Ting A, Morris PJ (1984) The detailed distribution of MHC class II antigens in normal human organs. Transplantation 38:293-298
24. Demetris AJ, Lasky S, Van Thiel DH, Starzl TE, Dekker A (1985) Pathology of hepatic transplantation: a review of 62 adult allograft recipients immunosuppressed with cyclosporine/steroid regimen. Am J Pathol 118:151-161
25. Gouw A, Houthoff H, Huitema S, Beelen JM Gips CH, Poppema S (1987) Expression of major histocompatibility antigens and replacement of donor cells by recipient ones in human liver grafts. Transplantation 43:291-296
26. Lautenschlager I, Taskinen E, Ikinen K, Lehto VP, Virtanen I, Hayry P (1984) Distribution of the major histocompatibility complex antigens on different components of human liver. Cell Immunol 85:191-200
27. Nagafuchi Y, Hobbs KEF, Thomas HC, Scheuer PJ (1985) Expression of beta-2-microglobulin on hepatocytes after liver transplantation. Lancet 1:551-554
28. So SKS, Snover DC, Ascher NL, Platt JL (1987) Class I major histocompatibility complex antigens are induced on hepatocytes in rejecting human liver grafts. Transplant Proc 19:2464-2465
29. Steinhoff G, Wonigeit K, Pichlmayr R (1988) Analysis of sequential changes in major histocompatibility complex expression in human liver grafts after transplantation. Transplantation 45:394-401
30. Takacs L, Szende B, Monostroi E, Rot A, Lapis K, Secseny A, Ando I (1983) Expression of HLA-DR antigens on bile duct cells of rejected liver transplant Lancet II:1500-1505
31. Markus BH, Demetris AJ, Saidman S, Fung JJ, Zeevi A, Starzl TE, Duquesnoy RJ (1988) Alloreactive T lymphocytes cultured from liver transplant biopsies: associations of HLA specificity with clinicopathological findings Clin Transplant 2:70-75
32. Colson YL, Markus BH, Zeevi A, Duquesnoy RJ (1990) Increased lymphocyte adherence to human arterial endothelial cell monolayers in the context of allorecognition. J Immunol 144: 2975-2984
33. Chapmann RW, Varghese Z, Gaul R, Patel G, Kokinon N, Sherlock S (1983) Association of primary sclerosing cholangitis with HLA-B8. Gut 24:38-41
34. Donaldson PT, Farrant JM, Wilkinson ML, Hayllar K, Portmann BC, Williams R (1991) Dual association of HLA DR2 and DR3 with primary sclerosing cholangitis. Hepatology 13:129-133
35. Galbraith RM, Eddleston ALWF, Smith MGM, Williams R, McSween RNM, Watkinson G, Dick H, Kennedy LA, Batchelor JR (1974) Histocompatibility antigens in active chronic hepatitis and primary biliary cirrhosis. BMJ 3:604-605
36. Lee YM, Kaplan MM (1995) Primary sclerosing cholangitis. N Engl J Med 332:924-933
37. Mackay I, Whittingham S, Mathews JD, Tait BD (1982) Genetic determinants of autoimmune chronic active hepatitis. In: Thomas HC, Miescher PA, Mueller-Eberhard HJ (eds) Immunological aspects of liver disease Springer. Berlin Heidelberg New York, pp 7-15
38. Mehal WZ, Lo YM, Wordsworth BP et al (1994) HLA DR4 is a marker for rapid disease progression in primary sclerosing cholangitis. Gastroenterology 106:160-167
39. Mondelli MU, Manns M, Ferrari C (1988) Does the immune response play a role in the pathogenesis of chronic liver disease? Arch Pathol Lab Med 112:489-497
40. Mota AH, Fainboim H, Fainboim L (1987) Association of chronic active hepatitis and HLA B35 in patients with hepatitis B virus. Tissue Antigens 30:238-240
41. Opelz G, Vogten AJM, Summerskill WHJ, Schalm SW, Terasaki PI (1977) HLA determinants in chronic active liver disease: possible relation of HLA-DW3 to prognosis. Tissue Antigens 10:63-64
42. Penner E, Grabner G, Dittrich H, Mayr WR (1977) HLA antigens in HBs antigen positive chronic active hepatitis. Tissue Antigens 10:63-64
43. Schrumpf E, Fausa O, Forre O, Dobloug JH, Ritland S, Thorsby E (1982) HLA antigens and immunoregulatory T cells in ulcerative colitis associated with hepatobiliary disease. Scand J Gastroenterol 17:187-191
44. Simon M, Alexandre JL, Fauchet R, Genetet B, Bourel M (1980) The genetics of hemochromatosis. Prog Med Genet 4:135-168
45. Stastny P, Ball EJ, Dry PJ, Nunez G (1983) The human immune response region (HLA-D) and disease susceptibility. Immunol Rev 70:113-153
46. Tait BD, Mackay IR (1982) HLA and alcoholic cirrhosis. Tissue Antigens 19:6-10
47. Tiwari JL, Terasaki PI (1985) HLA and disease associations. Springer. Berlin Heidelberg New York
48. Zinkernagel RM, Doherty PC (1979) MHC-restricted cytotoxic T cells: studies on the biological role of polymorphic major transplantation antigens determining T-cell restriction-specificity, function, and responsiveness. Adv Immunol 27:151-177
49. McMichael AJ, Ting A, Zweerink HJ, Askonal BA (1977) HLA restriction of cell-mediated lysis of influenza virus-infected human cells. Nature 270:524-526
50. Gehrz RC, Fuad S, Liu YNC, Bach F (1987) HLAclass II restricton of T helper cell response to cytomegalovirus (CMV). I. Immunogenetic control of restriction. J Immunol 138:3145-3151
51. Lindsley MD, Torpey DJ III, Rinaldo CR Jr (1986) HLA-DR-restricted cytotoxicity of cytomegalovirus-infected monocytes mediated by Leu-3-positive cells. J Immunol 136:3045-3051
52. Quinnan GV Jr, Kirmani N, Esber E, Saral R, Manischewitz JF, Rogers JL, Rook AH, Santos GW, Burns WH (1981) HLA-restricted cytotoxic T lymphocyte and nonthymic cytotoxic lymphocyte responses to cytomegalovirus infection of bone marrow transplant recipients. J Immunol 126:2036-2041
53. Quinnan GV, Burns WH, Kirmani N, Rook AH, Nimischewitz J, Jackson L, Santos GW, Saral R (1984) HLA-restricted cytotoxic T lymphocytes are an early immune response and important defense mechanism in cytomegalovirus infections. Rev Infect Dis 6:156-163
54. Yasukawa M, Zarling JM (1984) Human cytotoxic T cell clones directed against herpes simplex virus-infected cells. I. Lysis restricted by HLA class II MB and DR antigens. J Immunol 133:422-427
55. Calmus Y, Honnoun L, Dousset B, Wolff P, Miguet JP, Doffoel M, Gillet M, Cinqualbre J, Poupon R, Houssin D (1989) HLA class I matching is responsible for the hepatic lesions in viral B hepatitis after hepatic transplantation. J Hepatol 9:16
56. Gaur LK, Nelson K, Gretch D, Wile M, Strong DM, Corey L, Perkins J, Carithers R Jr (1994) Donor-recipient match at the HLA-DQB locus is associated with recurrence of chronic hepatitis following liver transplantation for end stage hepatitis C. Hum Immunol 40:7
57. Manez R, Mateo R, Tabasco J, Kusne S, Starzl TE, Duquesnoy RJ (1995) The influence of HLA donor-recipient compatibiltiy on the recurrence of HBV and HCV hepatitis after liver transplantation. Transplantation 59:640-642
58. Blancho G, Josien R, Douillard D, Bianon JD, Cesbron A, Soulillou JP (1992) Influence of HLA A-B-DR matching on CMV disease after renal transplantation: HLA-DR7 matched recipients are more susceptible to CMV disease. Transplantation 54:871-875
59. May AG, Betts RJ, Freeman RB, Andrus C (1978) An analysis of cytomegalovirus infection and HLA antigen matching on the outcome of renal transplantation. Ann Surg 187:110-117
60. Pouteil-Noble C, Betuel H, Raffaele P, Megri K, Louvier C, Lefrancois N, Bosshard S, Dubernard JM, Aymard M, Touraine JL (1991) Influence de la compatibilite HLA sur l'infection a cytomegalovirus en transplantation renale. Presse Med 27:20-24
61. Markus BH, Duquesnoy RJ, Gordon RD, Fung JJ, Vanek M, Klintmalm G, Bryan C, Van Thiel D, Starzl TE (1988) Histocompatibility and liver transplant outcome: does HLA exert a dualistic effect? Transplantation 46:372-377
62. Markus BH, Hakala TR, Tzakis A, Mitchell S, Marino IR, Gordon RD, Starzl TE (1988) Kidney transplantation in Pittsburgh: experience and innovations. In: Terasaki PI (ed) Clinical transplants 1987. UCLA Tissue Typing Laboratory, Los Angeles, pp 141-154
63. Donaldson PT, Alexander GJM, O'Grady JO, Neuberger J, Portmann B, Thick M, Davis H (1987) Evidence for an immune response to HLA class I antigens in the vanishing-bileduct syndrome after liver transplantation. Lancet 1:945-948
64. Donaldson PT, Underbill J, Doherty D, Hayllar K, Calne R, Tan KC, O'Grady J, Wight D, Portmann B, Williams R (1993) Influence of human leukocyte antigen matching on liver allograft survival and rejection: "the dualistic effect." Hepatology 17: 1008-1015
65. Opelz G for the Collaborative Transplant Study (1993) Newsletter 1. Heidelberg
66. Opelz G (1993) Preliminary analysis of HLA matching in pancreas and liver transplantation. Transplant Proc 25:2652-2653
67. Yagihashi A, Kobayashi M, Noguchi K, Konno A, Yoshida Y, Terasawa K, Starzl TE, Iwaki Y (1992) HLA matching effect in liver transplantation. Transplant Proc 24:2432-2433
68. Gunson BK, Hathaway M, Buckels JAC, Mayer AD, Elias E, McMaster P, Neuberger JM (1992) HLA matching in liver transplantation: a retrospective analysis. Transplant Proc 24: 2434-2435
69. Thorogood J for the l'Esprit Study Group (1993) Relationship between HLA compatibility and first liver allograft survival. Transplant Proc 25:2655-2656
70. Nikaein A, Backman L, Jennings L, Levy MF, Goldstein R, Gonwa T, Stone MJ, Klintmalm G (1994) HLA compatibility and liver transplant outcome. Improved patient survivalal by HLA and cross-matching. Transplantation 58:786-792
71. Gores GJ, Moore SB, Fisher LD, Powell FC, Dickson ER (1987) Primary biliary cirrhosis: associations with class II major histocompatibility complex antigens. Hepalology 7:889-892
72. Klein J (1986) Natural history of the major histocompatibility complex. Wiley New York
73. Bevan MJ (1975) The major histocompatibility complex determines susceptibility to cytotoxic T cells directed against minor histocompatibility antigens. J Exp Med 142:1349-1364
74. Goulmy E, Termijtelen A, Bradley BA, Van Rood JJ (1977) Y-antigen killing by T cells of women is restricted by HLA. Nature 266:544-545
75. Gordon RD, Simpson E, Samelson LE (1975) In vitro cell-mediated response to the male specific (H-Y) antigen in mice. J Exp Med 142:1108-1120
76. Pfeffer PF, Thorsby E (1982) HLA restricted cytotoxicity against male-specific (H-Y) antigen after acute rejection of an HLA identical sibling kidney. Transplantation 33:52-56