Increased anticoagulant activity of recombinant thrombomodulin modified with glycosaminoglycan

Biological and Pharmaceutical Bulletin

Volumn 21, Issue 4, 1998, Pages 375-381

  Edano, Toshiyuki ^a   Inoue, Keisuke ^a   Yoshizaki, Hideo ^a   Yamamoto, Susumu ^a   Komine, Noriko ^a   Tabunoki, Hiroko ^a   Sawada, Hironobu ^a   Koshi, Tomoyuki ^a   Murakami, Akira ^a   Wada, Yasushi ^a   Ohkuchi, Masao ^a  

^a KOWA COMPANY LTD   (Japan)

Author keywords

Anticoagulant; Disseminated intravascular coagulation; Hemorrhage; Thrombomodulin

Indexed keywords

ACTIVATED PROTEIN C; BLOOD CLOTTING FACTOR 10A; ENDOTOXIN; FIBRIN; FIBRINOGEN; FIBRINOGEN DEGRADATION PRODUCT; GLYCOSAMINOGLYCAN; RECOMBINANT THROMBOMODULIN; THROMBIN; THROMBIN RECEPTOR; THROMBOMODULIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANTICOAGULATION; ARTICLE; BLEEDING TIME; BLOOD CLOTTING TIME; CONTROLLED STUDY; DISSEMINATED INTRAVASCULAR CLOTTING; DOSE RESPONSE; DRUG POTENCY; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; MALE; MOUSE; NONHUMAN; PARTIAL THROMBOPLASTIN TIME; PROTHROMBIN TIME; RAT; THROMBIN TIME; THROMBOCYTE COUNT;

EID: 0031968229     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.21.375     Document Type: Article

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