Effect of platelet-activating factor-receptor antagonism on endotoxin- induced lung dysfunction in sheep

Journal of Applied Physiology

Volumn 84, Issue 5, 1998, Pages 1610-1614

  Snapper, James R ^a,b   Lu, Weixuan ^a   Lefferts, Peter L ^a   Thabes, John S ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Bronchi; Bronchial hyperreactivity; Lung; Pulmonary edema

Indexed keywords

ESCHERICHIA COLI ENDOTOXIN; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST;

ANIMAL EXPERIMENT; ARTICLE; BRONCHUS HYPERREACTIVITY; HYPOXEMIA; LEUKOPENIA; LUNG ARTERY PRESSURE; LUNG EDEMA; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; PULMONARY HYPERTENSION; SHEEP;

EID: 0031967905     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1998.84.5.1610     Document Type: Article

References (42)

1. Abu-Zidan, F. M., and S. Walther. Platelet activating factor antagonism improves cardiovascular function in non-hypotensive sepsis in pigs. Eur. J. Surg. 162: 499-504, 1996.
2. Abu-Zidan, F. M., S. Walther, and S. Lennquist. Role of platelet-activating factor antagonism in haemorrhagic shock in pigs. Eur. Surg. Res. 27: 379-388, 1995.
3. Abu-Zidan, F. M., S. Walther, and S. Lennquist. Role of platelet-activating factor antagonism in posthemorrhage septic shock in pigs. J. Trauma 41: 634-640, 1996.
4. Abu-Zidan, F. M., S. Walther, and S. Lennquist. Role of platelet-activating factor on cardiovascular dysfunction in postischemic shock in pigs. Eur. Surg. Res. 29: 133-141, 1997.
5. Ayala, A., and I. H. Chaudry. Platelet activating factor and its role in trauma, shock, and sepsis. New Horizons 4: 265-275, 1996.
6. Bahrami, S., H. Redl, M. Thurnher, C. Vogl, E. Paul, A. Schieber, and G. Schlag. Effect of PAF-antagonists in endotoxin shock-ovine and rat experiments. Prog. Clin.Biol Res 308: 931-936, 1989.
7. Baum, T. D., S. O. Heard, H. S. Feldman, C. A. Latka, and M. P. Fink. Endotoxin-induced myocardial depression in rats: effect of ibuprofen and SDZ 64-688, a platelet activating factor receptor antagonist. J. Surg. Res. 48: 629-634, 1990.
8. Begley, C. J., M. L. Ogletree, B. O. Meyrick, and K. L. Brigham. Modification of pulmonary responses to endotoxemia in awake sheep by steroidal and nonsteroidal anti-inflammatory agents. Am. Rev. Respir. Dis. 130: 1140-1146, 1984.
9. Bernard, G. R., J. M. Luce, C. L. Sprung, J. E. Rinaldo, R. M. Tate, W. J. Sibbald, K. Kariman, S. Higgins, R. Bradley, C. A. Metz, and T. R. Harris. High-dose corticosteroids in patients with the adult respiratory distress syndrome. N. Engl. J. Med. 317: 1565-1570, 1987.
10. Brigham, K. L., R. E. Bowers, and C. R. McKeen. Methylprednisolone prevention of increased lung vascular permeability following endotoxemia in sheep. J. Clin. Invest. 67: 1103-1110, 1981.
11. Brigham, K. L., and B. Meyrick. Endotoxin and lung injury. Am. Rev. Respir. Dis. 133: 913-927, 1986.
12. Chang, S., C. O. Feddersen, P. M. Henson, and N. F. Voelkel. Platelet-activating factor mediates hemodynamic changes and lung injury in endotoxin-treated rats. J. Clin. Invest. 79: 1498-1509, 1987.
13. Chang, S., S. Fernyak, and N. F. Voelkel. Beneficial effect of a platelet-activating factor antagonist, WEB 2086, on endotoxin-induced lung injury. Am. J. Physiol. 258 (Heart Circ. Physiol. 27): H153-H158, 1990.
14. Chen, T. Y., W. M. Zapol, and E. Greene. Protective effects of E5, an antiendotoxin monoclonal antibody, in the ovine pulmonary circulation. J. Appl. Physiol. 75: 233-239, 1993.
15. Christman, B. W., P. L. Lefferts, I. A. Blair, and J. R. Snapper. Effect of platelet-activating factor receptor antagonism on endotoxin-induced lung dysfunction in awake sheep. Am. Rev. Respir. Dis. 142: 1272-1278, 1990.
16. Christman, B. W., P. L. Lefferts, G. A. King, and J. R. Snapper. Role of circulating platelets and granulocytes in PAF-induced pulmonary dysfunction in awake sheep. J. Appl. Physiol. 64: 2033-2041, 1988.
17. Diez, F. L., M. L. Nieto, S. Fernandez-Gallardo, M. A. Gijon, and M. S. Crespo. Occupancy of platelet receptors for platelet-activating factor in patients with septicemia. J. Clin. Invest. 83: 1733-1740, 1989.
18. DuBois, A. B., S. Y. Bothelho, G. N. Bedell, R. Marshall, and J. H. Comroe. A rapid plethysmographic method measuring thoracic gas volume: a comparison with a nitrogen washout method for measuring functional residual capacity in normal subjects. J. Clin. Med. 35: 322-326, 1956.
19. Fletcher, J. R., A. G. DiSimone, and M. A. Earnest. Platelet activating factor receptor antagonist improves survival and attenuates eicosanoid release in severe endotoxemia. Ann. Surg. 211: 312-316, 1990.
20. Heuer, H., and J. Casals-Stenzel. The pathophysiological role of PAF in anaphylactic lung reaction in the guinea pig and in endotoxin shock evidenced by the specific PAF-antagonist WEB 2086. Prog. Clin. Biol. Res. 308: 925-930, 1989.
21. Heuer, H. O. Involvement of platelet-activating factor (PAF) in septic shock and priming as indicated by the effect of hetrazepinoic PAF antagonists. Lipids 26: 1369-1373, 1991.
22. Heuer, H. O., H. Darius, H. F. Lohmann, J. Meyer, M. Schierenberg, and N. Treese. Platelet-activating factor type activity in plasma from patients with septicemia and other diseases. Lipids 26: 1381-1385, 1991.
23. Kruse-Elliott, K. T., D. H. Albert, J. B. Summers, G. W. Carter, and J. J. Zimmerman. Attenuation of endotoxin-induced pathophysiology by a new potent PAF receptor antagonist. Shock 5: 265-273, 1996.
24. Kuhl, P. G., J. M. Bolds, J. E. Loyd, J. R. Snapper, and G. A. FitzGerald. Thromboxane receptor-mediated bronchial and hemodynamic responses in ovine endotoxemia. Am. J. Physiol. 254 (Regulatory Integrative Comp. Physiol. 23): R310-R319, 1988.
25. Lantz, R. C., G. E. Keller III, and R. Burrell. The role of platelet-activating factor in the pulmonary response to inhaled bacterial endotoxin. Am. Rev. Respir. Dis. 144: 167-172, 1991.
26. Ogletree, M. L., C. J. Begley, G. A. King, and K. L. Brigham. Influence of steroidal and nonsteroidal anti-inflammatory agents on the accumulation of arachidonic acid metabolites in plasma and lung lymph after endotoxemia in awake sheep. Measurements of prostacyclin and thromboxane metabolites and 12-HETE. Am. Rev. Respir. Dis. 133: 55-61, 1986.
27. Ogletree, M. L., and K. L. Brigham. Effects of cyclooxygenase inhibitors on pulmonary vascular responses to endotoxin in unanesthetized sheep. Prostaglandins Leukot. Med. 8: 489-502, 1982.
28. Olson, N. C., P. B. Joyce, and L. N. Fleisher. Role of platelet-activating factor and eicosanoids during endotoxin-induced lung injury in pigs. Am. J. Physiol. 258 (Heart Circ. Physiol. 27): H1674-H1686, 1990.
29. Ono, S., H. Mochizuki, and S. Tamakuma. A clinical study on the significance of platelet-activating factor in the pathophysiology of septic disseminated intravascular coagulation in surgery. Am. J. Surg. 171: 409-415, 1996.
30. Ono, S., S. Tamakuma, H. Mochizuki, M. Kinoshita, Y. Ohkusa, S. Aosasa, Y. Oda, and H. Ohe. Clinical and experimental studies on the role of platelet-activating factor (PAF) in the pathogenesis of septic DIC. Surg. Today 23: 228-233, 1993.
31. Parsons, P. E., G. S. Worthen, E. E. Moore, R. M. Tate, and P. M. Henson. The association of circulating endotoxin with the development of the adult respiratory distress syndrome. Am. Rev. Respir. Dis. 140: 294-301, 1989.
32. Qi, M., and S. B. Jones. Contribution of platelet activating factor to hemodynamic and sympathetic responses to bacterial endotoxin in conscious rats. Circulatory Shock 32: 153-163, 1990.
33. Salari, H., M. Demos, and A. Wong. Comparative hemodynamics and cardiovascular effect of endotoxin and platelet-activating factor in rat. Circulatory Shock 32: 189-207, 1990.
34. Sessler, C. N., F. L. Glauser, D. Davis, and A. A. Fowler III. Effects of platelet-activating factor antagonist SRI 63-411 on endotoxemia in sheep. J. Appl. Physiol. 65: 2624-2631, 1988.
35. Siebeck, M., J. Weipert, C. Keser, J. Kohl, M. Spannagl, W. Machleidt, and L. Schweiberer. A triazolodiazepine platelet activating factor receptor antagonist (WEB 2086) reduces pulmonary dysfunction during endotoxin shock in swine. J. Trauma 31: 942-950, 1991.
36. Smallbone, B. W., N. E. Taylor, and J. W. D. McDonald. Effects of L-652,731, a platelet-activating factor (PAF) receptor antagonist, on PAF-and complement-induced pulmonary hypertension in sheep. J. Pharmacol. Exp. Ther. 242: 1035-1040, 1987.
37. Snapper, J. R., A. A. Hutchison, M. L. Ogletree, and K. L. Brigham. Effects of cyclooxygenase inhibitors on the alterations in lung mechanics caused by endotoxemia in unanesthetized sheep. J. Clin. Invest. 72: 63-76, 1983.
38. Summers, J. B., D. H. Albert, S. K. Davidsen, R. G. Conway, J. H. Holms, T. J. Magoc, G. Luo, P. Tapang, D. A. Rhein, and G. W. Carter. ABT-299, a potent antagonist of platelet activating factor. Adv. Prostaglandin Thromboxane Leukot. Res. 23: 475-477, 1995.
39. The Veterans Administration Systemic Sepsis Cooperative Study Group. Effect of high-dose glucocorticoid therapy on mortality in patients with clinical signs of systemic sepsis. N. Engl. J. Med. 317: 659-665, 1987.
40. Trochtenberg, D. S., P. L. Lefferts, G. A. King, Y. S. Hwang, B. W. Christman, and J. R. Snapper. Effects of thromboxane synthase and cyclooxygenase inhibition on PAF-induced changes in lung function and arachidonic acid metabolism. Prostaglandins 44: 555-557, 1992.
41. Wheeler, A. P., W. D. Hardie, and G. Bernard. Studies of an antiendotoxin antibody in preventing the physiologic changes of endotoxemia in awake sheep. Am. Rev. Respir. Dis. 142: 775-781, 1990.
42. Zehr, K. J., R. S. Poston, P. C. Lee, K. Uthoff, P. Kumar, P. W. Cho, A. M. Gillinov, J. M. Redmond, J. A. Winkelstein, A. Herskowitz, and D. E. Cameron. Platelet activating factor inhibition reduces lung injury after cardiopulmonary bypass [see comments]. Ann. Thorac. Surg. 59: 328-335, 1995.