Simultaneous detection of p53 nuclear protein and chromosome aberrations on sections from formalin-fixed, paraffin-embedded breast cancer tissue

Chromosome Research

Volumn 6, Issue 3, 1998, Pages 233-235

  Bödvarsdóttir, Sigrídur K ^a   Sigurdsson, Stefan ^b   Steinarsdóttir, Margrét ^c   Eyfjörd, Jórunn E ^b   Ögmundsdóttir, Helga ^b   Anamthawat Jónsson, Kesara ^c  

^a Agricultural Research Institute Reykjavik   (Iceland)

^b ICELANDIC CANCER SOCIETY   (Iceland)

^c UNIVERSITY OF ICELAND   (Iceland)

Author keywords

Fluorescence in situ hybridization; Immunohistochemistry; p53; Tissue sections

Indexed keywords

NUCLEAR PROTEIN; PROTEIN P53;

ARTICLE; BREAST CANCER; CENTROMERE; CHROMOSOME 17; CHROMOSOME ABERRATION; CONTROLLED STUDY; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL;

BREAST NEOPLASMS; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN, PAIR 17; FEMALE; FORMALDEHYDE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; PARAFFIN; TISSUE FIXATION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0031966513     PISSN: 09673849     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (4)

1. Anamthawat-Jónsson K, Helsop-Harrison JS, Schwarzacher T (1996) Genomic in situ hybridization for whole chromosome and genome analysis. In: Clark M, ed. In situ Hybridization, Laboratory Companion. London: Chapman & Hall, pp 1-23.
2. Eyfjörd JE, Thorlacius S, Steinarsdottir M, Valgardsdottir R, Ögmundsdottir HM, Anamthawat-Jónsson K (1995) p53 Abnormalities and genomic instability in primary human breast carcinomas. Cancer Res 55: 646-651.
3. Thorlacius S, Thorgilsson B, Björnsson J, Tryggvadottir L, Börresen AL, Ögmundsdottir HM, Eyfjörd JE (1995) TP53 mutations and abnormal p53 protein staining in breast carcinomas related to prognosis. Eur J Cancer 31A: 1856-1861.
4. Weber-Matthiesen K (1996) Fluorescence immunophenotyping and interphase cytogenetics as a tool for investigation of neoplasms (FICTION). In: Clark M, ed. In Situ Hybridization, Laboratory Companion, London: Chapman & Hall, pp 67-90.