Characterization of vancomycin-resistant Enterococcus faecium isolates from the united states and their susceptibility in vitro to dalfopristin- quinupristin

Antimicrobial Agents and Chemotherapy

Volumn 42, Issue 5, 1998, Pages 1088-1092

  Eliopoulos, G M ^a,b,d   Wennersten, C B ^a   Gold, H S ^a,b   Schulin T ^a,b   Souli, M ^a,b   Farris, M G ^a   Cerwinka, S ^c   Nadler, H L ^c   Dowzicky, M ^c   Talbot, G H ^c   Moellering Jr , R C ^a,b  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c SANOFI   (France)

^d Deaconess Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; CHLORAMPHENICOL; CIPROFLOXACIN; DALFOPRISTIN PLUS QUINUPRISTIN; DOXYCYCLINE; ERYTHROMYCIN; GENTAMICIN; NOVOBIOCIN; RIFAMPICIN; STREPTOMYCIN; TEICOPLANIN; VANCOMYCIN;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERICIDAL ACTIVITY; BACTERIUM ISOLATION; CONTROLLED STUDY; DNA HYBRIDIZATION; DRUG ACTIVITY; ENTEROCOCCUS FAECALIS; GENETIC LINKAGE; GENOTYPE; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; UNITED STATES;

EID: 0031966356     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.42.5.1088     Document Type: Article

References (36)

1. Barry, A. L., P. C. Fuchs, and S. D. Brown. 1997. Provisional interpretive criteria for quinupristin/dalfopristin susceptibility tests. J. Antimicrob. Chemother. 39(Suppl. A):87-92.
2. Bonilla, H. F., M. B. Perri, C. A. Kauffman, and M. J. Zervos. 1996. Comparative in vitro activity of quinupristin/dalfopristin against multidrug resistant Enterococcus faecium. Diagn. Microbiol. Infect. Dis. 25:127-131.
3. Bush, L. M., J. Calmon, C. L. Cherney, M. Wendeler, P. Pitsakis, J. Poupard, M. E. Levison, and C. C. Johnson. 1989. High-level penicillin resistance among isolates of enterococci. Implications for treatment of enterococcal infections. Ann. Intern. Med. 110:515-520.
4. Centers for Disease Control and Prevention. 1993. Nosocomial enterococci resistant to vancomycin - United States, 1989-1993. Morbid. Mortal. Weekly Rep. 42:597-599.
5. Cercenado, E., S. Ünal, C. T. Eliopoulos, L. G. Rubin, H. D. Isenberg, R. C. Moellering, Jr., and G. M. Eliopoulos. 1995. Characterization of vancomycin-resistance in Enterococcus durans. J. Antimicrob. Chemother. 36:821-825.
6. Chow, J. W., S. M. Donabedian, and M. J. Zervos. 1997. Emergence of increased resistance to quinupristin/dalfopristin during therapy for Enterococcus faecium bacteremia. Clin. Infect. Dis. 24:90-91.
7. Clark, N. C., R. C. Cooksey, B. C. Hill, J. M. Swenson, and F. C. Tenover. 1993. Characterization of glycopeptide-resistant enterococci from U.S. hospitals. Antimicrob. Agents Chemother. 37:2311-2317.
8. Collins, L. A., G. J. Malanoski, G. M. Eliopoulos, C. B. Wennersten, M. J. Ferraro, and R. C. Moellering, Jr. 1993. In vitro activity of RP59500, an injectable streptogramin antibiotic, against vancomycin-resistant gram-positive organisms. Antimicrob. Agents Chemother. 37:598-601.
9. Coque, T. M., and B. E. Murray. 1995. Identification of Enterococcus faecalis strains by DNA hybridization and pulsed-field gel electrophoresis. J. Clin. Microbiol. 33:3368-3369.
10. Costa, Y., M. Galimand, R. Leclercq, J. Duval, and P. Courvalin. 1993. Characterization of the chromosomal aac(6′)-Ii gene specific for Enterococcus faecium. Antimicrob. Agents Chemother. 37:1896-1903.
11. Edmond, M. B., J. F. Ober, J. D. Dawson, D. L. Weinbaum, and R. P. Wenzel. 1996. Vancomycin-resistant enterococcal bacteremia: natural history and attributable mortality. Clin. Infect. Dis. 23:1234-1239.
12. Eliopoulos, G. M. 1996. Antibiotic resistance in Enterococcus species: an update. Curr. Clin. Top. Infect. Dis. 16:21-51.
13. Eliopoulos, G. M., C. Wennersten, S. Zighelboim-Daum, E. Reiszner, D. Goldmann, and R. C. Moellering, Jr. 1988. High-level resistance to gentamicin in clinical isolates of Streptococcus (Enterococcus) faecium. Antimicrob. Agents Chemother. 32:1528-1532.
14. Etienne, S. D., G. Montay, A. Le Liboux, A. Frydman, and J. J. Garaud. 1992. A phase I, double-blind, placebo-controlled study of the tolerability and pharmacokinetic behavior of RP 59500. J. Antimicrob. Chemother. 30: (Suppl. A):123-131.
15. Fass, R. J. 1991. In vitro activity of RP 59500, a semisynthetic injectable pristinamycin, against staphylococci, streptococci, and enterococci. Antimicrob. Agents Chemother. 35:553-559.
16. Freeman, C., A. Robinson, B. Cooper, M. Mazens-Sullivan, R. Quintiliani, and C. Nightingale. 1995. In vitro antimicrobial susceptibility of glycopeptide-resistant enterococci. Diagn. Microbiol. Infect. Dis. 21:47-50.
17. Gold, H. S., S. Ünal, E. Cercenado, C. Thauvin-Eliopoulos, G. M. Eliopoulos, C. B. Wennersten, and R. C. Moellering, Jr. 1993. A gene conferring resistance to vancomycin but not teicoplanin in isolates of Enterococcus faecalis and Enterococcus faecium demonstrates homology with vanB, vanA, and vanC genes of enterococci. Antimicrob. Agents Chemother. 37:1604-1609.
18. Grayson, M. L., G. M. Eliopoulos, C. B. Wennersten, K. L. Ruoff, P. C. De Girolami, M. J. Ferraro, and R. C. Moellering, Jr. 1991. Increasing resistance to β-lactam antibiotics among clinical isolates of Enterococcus faecium: a 22-year review at one institution. Antimicrob. Agents Chemother. 35:2180-2184.
19. Handwerger, S., M. J. Pucci, and A. Kolokathis. 1990. Vancomycin resistance is encoded on a pheromone response plasmid in Enterococcus faecium 228. Antimicrob. Agents Chemother. 34:358-360.
20. Hardalo, C, M. Rigsby, L. Chen, C. Dykewicz, J. Elmore, S. Nagy-Agren, P. Wetherill, S. Edberg, and W. Hierholzer. 1993. Chloramphenicol treatment of resistant Enterococcus faecium infections, abstr. 110. In Program and abstracts of the Infectious Diseases Society of America Annual Meeting.
21. Hayden, M. K., G. M. Trenholme, J. E. Schultz, and D. F. Sahm. 1993. In vivo development of teicoplanin resistance in a VanB Enterococcus faecium isolate. J. Infect. Dis. 167:1224-1227.
22. Johnson, C. C., L. Slavoski, M. Schwartz, P. May, P. G. Pitsakis, A. L. Shur, and M. E. Levison. 1995. In vitro activity of RP 59500 (quinupristin/dalfo-pristin) against antibiotic-resistant strains of Streptococcus pneumoniae and enterococci. Diagn. Microbiol. Infect. Dis. 21:169-173.
23. Jones, R. N., H. S. Sader, M. E. Erwin, S. A. Anderson, and the Enterococcus Study Group. 1995. Emerging multiply resistant enterococci among clinical isolates. I. Prevalence data from 97 medical center surveillance study in the United States. Diagn. Microbiol. Infect. Dis. 21:85-93.
24. Linden, P., A. W. Pasculle, R. Manez, D. Silverman, D. J. Kramer, and S. Kusne. 1993. Utilization of novobiocin and ciprofloxacin for the treatment of serious infection due to vancomycin resistant Enterococcus faecium, abstr. 1027, p. 307. Program and abstracts of the 33rd Interscience Conference on Antimicrobial Agents and Chemotherapy. American Society for Microbiology, Washington, D.C.
25. Linden, P. K., A. W. Pasculle, R. Manez, D. J. Kramer, J. J. Fung, A. D. Pinna, and S. Kusne. 1996. Differences in outcomes for patients with bacteremia due to vancomycin-resistant Enterococcus faecium or vancomycin-susceptible E. faecium. Clin. Infect. Dis. 22:663-670.
26. Montecalvo, M. A., H. Horowitz, G. P. Wormser, K. Seiter, and C. A. Carbonaro. 1995. Effect of novobiocin-containing antimicrobial regimens on infection and colonization with vancomycin-resistant Enterococcus faecium. Antimicrob. Agents Chemother. 39:794.
27. National Committee for Clinical Laboratory Standards. 1993. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically-third edition; approved standard. NCCLS document M7-A3. National Committee for Clinical Laboratory Standards, Villanova, Pa.
28. National Committee for Clinical Laboratory Standards. 1993. Performance standards for antimicrobial disk susceptibility tests-fifth edition; approved standard. NCCLS document M2-A5. National Committee for Clinical Laboratory Standards, Villanova, Pa.
29. Norris, A. H., J. P. Reilly, P. H. Edelstein, P. J. Brennan, and M. G. Schuster. 1995. Chloramphenicol for the treatment of vancomycin-resistant enterococcal infections. Clin. Infect. Dis. 20:1137-1144.
30. Rende-Fournier, R., R. Leclercq, M. Galimand, J. Duval, and P. Courvalin. 1993. Identification of the satA gene encoding a streptogramin A acetyltransferase in Enterococcus faecium BM4145. Antimicrob. Agents Chemother. 37:2119-2125.
31. Rice, L. B., G. M. Eliopoulos, C. Wennersten, D. Goldmann, G. A. Jacoby, and R. C. Moellering, Jr. 1991. Chromosomally mediated β-lactamase production and gentamicin resistance in Enterococcus faecalis. Antimicrob. Agents Chemother. 35:272-276.
32. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. p. 1.98-1.99. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
33. Shay, D. K., S. A. Maloney, M. Montecalvo, S. Banerjee, G. P. Wormser, M. J. Arduino, L. A. Bland, and W. R. Jarvis. 1995. Epidemiology and mortality risk of vancomycin-resistant enterococcal bloodstream infections. J. Infect. Dis. 172:993-1000.
34. Venditti, M., A. Tarasi, V. Gelfusa, E. Nicastri, A. Penni, and P. Martino. 1993. Antimicrobial susceptibilities of enterococci isolated from hospitalized patients. Antimicrob. Agents Chemother. 37:1190-1192.
35. Woodford, N., B. L. Jones, Z. Baccus, H. A. Ludlam, and D. F. Brown. 1995. Linkage of vancomycin and high-level gentamicin resistance genes on the same plasmid in a clinical isolate of Enterococcus faecalis. J. Antimicrob. Chemother. 35:179-184.
36. Woodford, N., D. Morrison, A. P. Johnson, and R. C. George. 1993. Antimicrobial resistance amongst enterococci isolated in the United Kingdom: a reference laboratory perspective. J. Antimicrob. Chemother. 32:344-346.