Quantitation of Glandular Gastric Changes in Rats Given a Proton Pump Inhibitor for 3 Months with Emphasis on Sampling Scheme Selection

Toxicologic Pathology

Volumn 26, Issue 3, 1998, Pages 403-410

  White, S L ^a   Smith, W C ^a   Fisher, L F ^a   Gatlin, C L ^a   Hanasono, G K ^a   Jordan, W H ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

chromogranin A; enterochromaffin like cell; image analysis; LY307640 sodium; morphometry; stomach

Indexed keywords

CHROMOGRANIN A; HISTAMINE H2 RECEPTOR ANTAGONIST; PROTON PUMP INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DENSITY; CELL HYPERPLASIA; CONTROLLED STUDY; ENTEROCHROMAFFIN CELL; FEMALE; HYPERGASTRINEMIA; IMAGE ANALYSIS; LONG TERM CARE; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; QUANTITATIVE DIAGNOSIS; RAT; SAMPLING; STOMACH ACID SECRETION; STOMACH FUNDUS; STOMACH GLAND; STOMACH MUCOSA; STOMACH VOLUME;

2-PYRIDINYLMETHYLSULFINYLBENZIMIDAZOLES; ANIMALS; BENZIMIDAZOLES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENTEROCHROMAFFIN-LIKE CELLS; ENZYME INHIBITORS; FEMALE; GASTRIC MUCOSA; IMAGE PROCESSING, COMPUTER-ASSISTED; MALE; OMEPRAZOLE; ORGAN SIZE; PROTON PUMPS; PROTON-TRANSLOCATING ATPASES; RATS; RATS, SPRAGUE-DAWLEY; SAMPLE SIZE; SEX FACTORS; STOMACH;

ANIMALIA;

EID: 0031965505     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1177/019262339802600315     Document Type: Article

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