Transient thrombocytopenia produced by administration of macrophage colony-stimulating factor: Investigations of the mechanism

Blood

Volumn 91, Issue 1, 1998, Pages 89-99

  Baker, Georgiann R ^a   Levin, Jack ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLONY STIMULATING FACTOR 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COLONY FORMING CELL; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; MEGAKARYOCYTE; MOUSE; NONHUMAN; POLYPLOIDY; PRIORITY JOURNAL; SPLENECTOMY; THROMBOCYTE COUNT; THROMBOCYTE LIFESPAN; THROMBOCYTOPENIA; THROMBOCYTOPOIESIS;

EID: 0031965269     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v91.1.89.89_89_99     Document Type: Article

References (61)

1. Ralph P, Sampson-Johannes A: Macrophage growth and stimulating factor, M-CSF. Prog Clin Biol Res 338:43, 1990
2. Roth P, Stanley ER: The biology of CSF-1 and its receptor. Curr Top Microbiol Immunol 181:141, 1992
3. Stanley ER, Guilbert LJ, Tushinski RJ, Bartelmez SH: CSF-1-A mononuclear phagocyte lineage-specific hemopoietic growth factor. J Cell Biochem 21:151, 1983
4. Metcalf D: Studies on colony formation in vitro by mouse bone marrow cells. II. Action of colony stimulating factor. J Cell Physiol 76:89, 1970
5. Nemunaitis J, Singer JW: Macrophage colony-stimulating factor: Biology and clinical applications, in Armitage JO and Antman KH (eds): High-dose Cancer Therapy. Pharmacology, Hematopoietins, Stem Cells. Baltimore, MD, Williams & Wilkins, 1992, p 344
6. Hume DA, Pavli P, Donahue RE, Fidler IJ: The effect of human recombinant macrophage colony-stimulating factor (CSF-1) on the murine mononuclear phagocyte system in vivo. J Immunol 141:3405, 1988
7. Cecchini MG, Dominguez MG, Mocci S, Wetterwald A, Felix R, Fleisch H, Chisholm O, Hofstetter W, Pollard JW, Stanley ER: Role of colony stimulating factor-1 in the establishment and regulation of tissue macrophages during postnatal development of the mouse. Development 120:1357, 1994
8. Wiktor-Jedrzejczak W, Urbanowska E, Aukerman SL, Pollard JW, Stanley ER, Ralph P, Ansari AA, Sell KW, Szperl M: Correction by CSF-1 of defects in the osteopetrotic op/op mouse suggests local, developmental, and humoral requirements for this growth factor. Exp Hematol 19:1049, 1991
9. Stanley ER: Colony stimulating factor-1 (macrophage colony stimulating factor), in Thomson AW (ed): The Cytokine Handbook. San Diego, CA, Academic, 1994, p 387
10. Bartocci A, Mastrogiannis DS, Migliorati G, Stockert RJ, Wolkoff AW, Stanley ER: Macrophages specifically regulate the concentration of their own growth factor in the circulation. Proc Natl Acad Sci USA 84:6179, 1987
11. Garnick MB, Stoudemire JB: Preclinical and clinical evaluation of recombinant human macrophage colony-stimulating factor (rhM-CSF). Int J Cell Cloning 8:356, 1990
12. Munn DH, Garnick MB, Cheung N-KV: Effects of parenteral recombinant human macrophage colony-stimulating factor on monocyte number, phenotype, and antitumor cytotoxicity in nonhuman primates. Blood 75:2042, 1990
13. Cole DJ, Sanda MG, Yang JC, Schwartzentruber DJ, Weber J, Ettinghausen SE, Pockaj BA, Kim HI, Levin RD, Pogrebniak HW, Balkissoon J, Fenton RM, DeBarge LR, Kaye J, Rosenberg SA, Parkinson DR: Phase I trial of recombinant human macrophage colony-stimulating factor administered by continuous intravenous infusion in patients with metastatic cancer. J Natl Cancer Inst 86:39, 1994
14. Redman BG, Flaherty L, Chou TH, Kraut M, Martino S, Simon M, Valdivieso M, Groves E: Phase I trial of recombinant macrophage colony-stimulating factor by rapid intravenous infusion in patients with cancer. J Immunother 12:50, 1992
15. Garnick MB, O'Reilly RJ: Clinical promise of new hematopoietic growth factors: M-CSF, IL-3, IL-6. Hematol Oncol Clin North Am 3:495, 1989
16. Vitt CR, Fidler JM, Ando D, Zimmerman RJ, Aukerman SL: Antifungal activity of recombinant human macrophage colony-stimulating factor in models of acute and chronic candidiasis in the rat. J Infect Dis 169:369, 1994
17. Munn DH, Cheung N-KV: Preclinical and clinical studies of macrophage colony-stimulating factor. Semin Oncol 19:395, 1992
18. Bock SN, Cameron RB, Kragel P, Mulé JJ, Rosenberg SA: Biological and antitumor effects of recombinant human macrophage colony-stimulating factor in mice. Cancer Res 51:2649, 1991
19. Stoudemire JB, Garnick MB: Effects of recombinant human macrophage colony-stimulating factor on plasma cholesterol levels. Blood 77:750, 1991
20. Sherr CJ, Stanley ER: Colony-stimulating factor 1 (macrophage colony-stimulating-factor), in Sporn MB and Roberts AB (eds): Handbook of Experimental Pharmacology, vol. 95/I, Peptide Growth Factors and Their Receptors. Berlin, Germany, Springer-Verlag, 1990, p 667
21. Johnson CW, Nachtman JP, Cimprich RE, Moon H-L, Mills SE, Beckendorf J, Levine BS, Long RC, Fuller GB, Losos G, Provencher A, Stoll RE: Clinical and histopathological effects of M-CSF in laboratory animals, in Richter GW, Solez K (eds): International Review of Experimental Pathology, vol 34. San Diego, CA, Academic, 1993, p 189
22. Zamkoff KW, Hudson J, Groves ES, Childs A, Konrad M, Rudolph AR: A phase I trial of recombinant human macrophage colony-stimulating factor by rapid intravenous infusion in patients with refractory malignancy. J Immunother 11:103, 1992
23. Schaub RG, Bree MP, Hayes LL, Rudd MA, Rabbani L, Loscalzo J, Clinton SK: Recombinant human macrophage colony-stimulating factor reduces plasma cholesterol and carrageenan granuloma foam cell formation in Watanabe heritable hyperlipidemic rabbits. Arterioscler Thromb 14:70, 1994
24. Weiner LM, Li W, Holmes M, Catalano RB, Dovnarsky M, Padavic K, Alpaugh RK: Phase I trial of recombinant macrophage colony-stimulating factor and recombinant γ-interferon: Toxicity, monocytosis, and clinical effects. Cancer Res 54:4084, 1994
25. Jakubowski AA, Bajoran DF, Templeton MA, Chapman PB, Cody BV, Thaler H, Tao Y, Filippa DA, Williams L, Sherman ML, Garnick MB, Houghton AN: Phase I study of continuous-infusion recombinant macrophage colony-stimulating factor in patients with metastatic melanoma. Clin Cancer Res 2:295, 1996
26. Davis E, Corash L, Baker G, Mok Y, Hill RJ, Levin J: Splenic thrombopoiesis after bone marrow ablation with radiostrontium: A murine model. J Lab Clin Med 116:879, 1990
27. Guilbert LJ, Stanley ER: Specific interaction of murine colony-stimulating factor with mononuclear phagocytic cells. J Cell Biol 85:153, 1980
28. DeLamarter JF, Hession C, Semon D, Gough NM, Rothenbuhler R, Mermod J-J: Nucleotide sequence of a cDNA encoding murine CSF-1 (macrophage-CSF). Nucleic Acids Res 15:2389, 1987
29. Flanagan JG, Leder P: The kit ligand: A cell surface molecule altered in steel mutant fibroblasts. Cell 63:185, 1990
30. Tong M, Seth P, Penington DG: Proplatelets and stress platelets. Blood 69:522, 1987
31. Levin J, Levin FC, Metcalf D: The effects of acute thrombocytopenia on megakaryocyte-CFC and granulocyte-macrophage-CFC in mice: Studies of bone marrow and spleen. Blood 56:274, 1980
32. Corash L, Levin J, Mok Y, Baker G, McDowell J: Measurement of megakaryocyte frequency and ploidy distribution in unfractionated murine bone marrow. Exp Hematol 17:278, 1989
33. Baker GR, Sullam PM, Levin J: A simple, fluorescent method to internally label platelets suitable for physiological measurements. Am J Hematol 56:17, 1997
34. Dale GL, Wolf RF, Hynes LA, Friese P, Burstein SA: Quantitation of platelet life span in splenectomized dogs. Exp Hematol 24:518, 1996
35. 51Cr-platelet survival study. Am J Hematol 8:281, 1980
36. Su D, Roth RI, Yoshida M, Levin J: Hemoglobin increases mortality from bacterial endotoxin. Infect Immun 65:1258, 1997
37. Stanley ER: The macrophage colony-stimulating factor, CSF-1. Methods Enzymol 116:564, 1985
38. Janowska-Wieczorek A, Belch AR, Jacobs A, Bowen D, Padua R-A, Paietta E, Stanley ER: Increased circulating colony-stimulating factor-1 in patients with preleukemia, leukemia, and lymphoid malignancies. Blood 77:1796, 1991
39. Gilbert HS, Praloren V, Stanley ER: Increased circulating CSF-1 (M-CSF) in myeloproliferative disease: Association with myeloid metaplasia and peripheral bone marrow extension. Blood 74:1231, 1989
40. Chenaille PJ, Steward SA, Ashmun RA, Jackson CW: Prolonged thrombocytosis in mice after 5-fluorouracil results from failure to down-regulate megakaryocyte concentration. An experimental model that dissociates regulation of megakaryocyte size and DNA content from megakaryocyte concentration. Blood 76:508, 1990
41. Radley JM, Hodgson GS, Thean LE, Zangheri O, Levin J: Increased megakaryocytes in the spleen during rebound thrombocytosis following 5-fluorouracil. Exp Hematol 8:1129, 1980
42. Corash L, Chen HY, Levin J, Baker G, Lu H, Mok Y: Regulation of thrombopoiesis: Effects of the degree of thrombocytopenia on megakaryocyte ploidy and platelet volume. Blood 70:177, 1987
43. Levin J: An overview of megakaryocytopoiesis, in Breton-Gorius J, Levin J, Nurden AT, Williams N (eds): Molecular Biology and Differentiation of Megakaryocytes. New York, NY, Wiley-Liss, 1990, p 1
44. Bukowski RM, Budd GT, Gibbons JA, Bauer RJ, Childs A, Antal J, Finke J, Tuason L, Lorenzi V, McLain D, Tubbs R, Edinger M, Thomassen MJ: Phase I trial of subcutaneous recombinant macrophage colony-stimulating factor: Clinical and immunomodulatory effects. J Clin Oncol 12:97, 1994
45. Wong K-F, Chan JKC: Reactive hemophagocytic syndrome - a clinicopathologic study of 40 patients in an Oriental population. Am J Med 93:177, 1992
46. Cline MJ: Histiocytes and histiocytosis. Blood 84:2840, 1994
47. Tsuda H: Possible role of macrophage-colony stimulating factor in the development of hemophagocytic syndrome. Eur J Haematol 54:197, 1995 (letter)
48. Vargaftig BB, Lefort J: Acute hypotension due to carrageenan, arachidonic acid and slow reacting substance C in the rabbit: Role of platelets and nature of pharmacological antagonism. Eur J Pharmacol 43:125, 1977
49. Schuening FG, Storb R, Goehle S, Nash R, Graham TC, Appelbaum FR, Hackman R, Sandmaier BM, Urdal DL: Stimulation of canine hematopoiesis by recombinant human granulocyte-macrophage colony-stimulating factor. Exp Hematol 17:889, 1989
50. Nash RA, Burstein SA, Storb R, Yang W, Abrams K, Appelbaum FR, Boone T, Deeg HJ, Durack LD, Schuening FG, McDonough S, Moore P, Nelp WB, Slichter S: Thrombocytopenia in dogs induced by granulocyte-macrophage colony-stimulating factor: Increased destruction of circulating platelets. Blood 86:1765, 1995
51. Lindemann A, Herrmann F, Oster W, Haffner G, Meyenburg W, Souza LM, Mertelsmann R: Hematologic effects of recombinant human granulocyte colony-stimulating factor in patients with malignancy. Blood 74:2644, 1989
52. Cohen AM, Zsebo KM, Inoue H, Hines D, Boone TC, Chazin VR, Tsai L, Ritch T, Souza LM: In vivo stimulation of granulopoiesis by recombinant human granulocyte colony-stimulating factor. Proc Natl Acad Sci USA 84:2484, 1987
53. Williams DE, Morrissey PJ: Alterations in megakaryocyte and platelet compartments following in vivo IL-1βadministration to normal mice. J Immunol 142:4361, 1989
54. Neta R, Monroy R, MacVittie TJ: Utility of interleukin-1 in therapy of radiation injury as studied in small and large animal models. Biotherapy 1:301, 1989
55. Paciucci PA, Mandeli J, Oleksowicz L, Ameglio F, Holland JF: Thrombocytopenia during immunotherapy with interleukin-2 by constant infusion. Am J Med 89:308, 1990
56. Edwards MJ, Heniford BT, Klar EA, Doak KW, Miller FN: Pentoxifylline inhibits interleukin-2-induced toxicity in C57BL/6 mice but preserves antitumor efficacy. J Clin Invest 90:637, 1992
57. Andrews RG, Knitter GH, Bartelmez SH, Langley KE, Farrar D, Hendren RW, Appelbaum FR, Bernstein ID, Zsebo KM: Recombinant human stem cell factor, a c-kit ligand, stimulates hematopoiesis in primates. Blood 78:1975, 1991
58. Schuening FG, Appelbaum FR, Deeg HJ, Sullivan-Pepe M, Graham TC, Hackman R, Zsebo KM, Storb R: Effects of recombinant canine stem cell factor, a c-kit ligand, and recombinant granulocyte colony-stimulating factor on hematopoietic recovery after otherwise lethal total body irradiation. Blood 81:20, 1993
59. Nash RA, Schuening F, Appelbaum F, Hammond WP, Boone T, Morris CF, Slichter S, Storb R: Molecular cloning and in vivo evaluation of canine granulocyte-macrophage colony-stimulating factor. Blood 78:930, 1991
60. Grossmann A, Lenox J, Ren HP, Humes JM, Forstrom JW, Kaushansky K, Sprugel KH: Thrombopoietin accelerates platelet, red blood cell, and neutrophil recovery in myelosuppressed mice. Exp Hematol 24:1238, 1996
61. Levin J: Thrombopoietin - clinically realized? N Engl J Med 336:434, 1997 (editorial)