A randomized controlled double blind study of zuclopenthixol acetate compared to haloperidol in acute psychosis

Human Psychopharmacology

Volumn 13, Issue 1, 1998, Pages 17-20

  Brook, S ^a   Berk, M ^a   Selemani, S ^a   Kolloori, J ^a   Nzo, I ^a  

^a UNIVERSITY OF THE WITWATERSRAND MEDICAL SCHOOL   (South Africa)

Author keywords

Haloperidol; Psychosis; Schizophrenia; Schizophreniform disorder; Zuclopenthixol

Indexed keywords

HALOPERIDOL; ZUCLOPENTHIXOL ACETATE;

ACUTE PSYCHOSIS; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG TOLERABILITY; FEMALE; HUMAN; MALE; ORAL DRUG ADMINISTRATION; PARENTERAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; SCHIZOPHRENIA;

EID: 0031965044     PISSN: 08856222     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1077(199801)13:1<17::AID-HUP937>3.0.CO;2-G     Document Type: Article

References (12)

1. Amdisen, A., Aaes-Jorgensen, T., Thomsen, N. J., Madsen, V. T. and Nielsen, M. S. (1986). Serum concentrations and clinical effect of zuclopenthixol acetate in acutely disturbed, psychotic patients treated with zuclopenthixol acetate in Viscoleo. Psychopharmacology, 90, 412-416.
2. Amdisen, A., Nielsen, M., Dencker, S. J., Fensbo, C., Ahlfors, U. G., Gravem, A., Baastrup, P. C., Bjerkenstedt, L., Gunby, B., Wiesel, F-A., Lindholm, H., Rafaelsen, O. J., Fredslund-Andersen, K., Thomsen, N. J., Resell, I., Pakarinen, P., Harma, P., Amthor, K. F., Kastberg, S. and Abelskov, J. (1987). Zuclopenthixol acetate in Viscoleo - a new drug formulation. Acta Psychiatrica Scandinavica, 75, 99-107.
3. Baastrup, P. C., Ahlfors, U. G., Bjerkenstedt, L., Dencker, S. J., Fensbo, C., Gravem, A., Pedersen, V., Elgen, K., Brekke, B., Fredslund-Andersen, K., Lindholm, H., Lybeck, I., Morawski, R., Nummi, K., Silfverhjelm, H., Vartiainen, H., Wiesel, F. A. and Aarvold, A. (1993). A controlled Nordic multicentre study of zuclopenthixol acetate in oil solution, haloperidol and zuclopenthixol in the treatment of acute psychosis. Acta Psychiatrica Scandinavica, 87, 48-58.
4. Bobon, D. and De Bleeker, E. (1990). Zuclopenthixol acetate and haloperidol in acute psychotic patients - a randomized multicentre study. In: New Strategies in the Treatment of Aggressive Acutely Psychotic Patients, Wistedt, B. (Ed.), Excerpta Medica, Amsterdam, pp. 47-59.
5. Chakravarti, S. K., Muthu, A., Muthu, P. K., Naik, P. and Pinto, R. T. (1990). Zuclopenthixol acetate (5% in Viscoleo): single dose treatment for acutely disturbed psychotic patients. Current Medical Research and Opinion, 12, 58-65.
6. Chouinard, G., Safadi, G. and Beauclair, L. (1994). A double-blind controlled study of intramuscular zuclopenthixol acetate and liquid oral haloperidol in the treatment of schizophrenic patients with acute exacerbations. Journal of Clinical Psychopharmacology, 14, 377-384.
7. Farid, B. T., Qureshi, M. J. H., Mortimer, A. M., Soliman, A. H. M., Lodge, G., Matthews, B. J., McEvedy, C., Ghadiali, H. H., Sourindhrin, I., Gill, P. V., Khoosal, D. I., Levine, S. and Roy, L. K. (1991). A new concept in the management of acute psychosis: Zuclopenthixol acetate (5% in viscoleo). European Journal of Clinical Research, 1, 13-23.
8. Hekkilä, L., Eliander, H., Vartiainen, H., Turunen, M. and Pedersen, V. (1992). Zuclopenthixol and haloperidol in patients with acute psychotic states. A double blind, multi centre study. Current Medical Research and Opinion, 12, 594-603.
9. Matar, A. M., Abdel-Mawgoud, M. and Skov, S. (1990). Zuclopenthixol: A new generation of antipsychotic drugs. An open trial. Journal of Clinical Psychopharmacology, 10, 283-286.
10. Predescu, V., Ciurezu, T., Marinescu, A., Sarbulescu, A., Tudorache, B., Dan, I., Pirojynsky, T. and Randasu, S. (1991). An open clinical study of Clopixol Accuphase (Zuclopenthixol Acetate) treatment followed by Clopixol Depot in acute psychoses with long term tendency. Romanian Journal of Neurology and Psychiatry, 29, 215-219.
11. Schlosberg, A. and Barr, F. (1991). Zuclopenthixol acetate in viscoleo in acutely disturbed psychotic patients. Israel Journal of Psychiatry and Related Sciences, 28, 60-63.
12. Tan, C. H., Low, B. L., Ng, L. L., Khoo, Y. M. and Lee, H. S. (1993). Clinical evaluation and serum concentration of zuclopenthixol acetate in Psychotic Asian patients: a single dose preliminary study. Therapeutic Drug Monitoring, 15, 108-112.