ONO-5046, an elastase inhibitor, attenuates liver mitochondrial dysfunction after endotoxin

Critical Care Medicine

Volumn 26, Issue 1, 1998, Pages 138-141

  Kudoh, Akira ^a   Kudoh, Emiko ^a   Ishihara, Hironori ^a   Matsuki, Akitomo ^a  

^a HIROSAKI UNIVERSITY   (Japan)

Author keywords

Arterial blood pressure; Critical illness; Endotoxin; Energy metabolism; Escherichia coli; Gram negative bacteria; Guinea pigs; Liver; Mitochondria; Neutrophil elastase; Shock

Indexed keywords

SIVELESTAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DOSE RESPONSE; DRUG EFFECT; ENDOTOXEMIA; ENERGY METABOLISM; ENZYME INHIBITION; GUINEA PIG; INTRAVENOUS DRUG ADMINISTRATION; LIVER DYSFUNCTION; LIVER MITOCHONDRION; MALE; MEAN ARTERIAL PRESSURE; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXYGEN TRANSPORT; PRIORITY JOURNAL;

ADENOSINE DIPHOSPHATE; ANIMALS; BLOOD PRESSURE; DOSE-RESPONSE RELATIONSHIP, DRUG; ESCHERICHIA COLI; GLYCINE; GUINEA PIGS; KETONE BODIES; LEUKOCYTE ELASTASE; LIPOPOLYSACCHARIDES; LIVER DISEASES; MALE; MITOCHONDRIA, LIVER; OXYGEN; PHOSPHORYLATION; RESPIRATION; SERINE PROTEINASE INHIBITORS; SULFONAMIDES;

EID: 0031964478     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-199801000-00029     Document Type: Article

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