Topical tretinoin replenishes CD1a-positive epidermal Langerhans cells in chronically photodamaged human skin

Journal of Cutaneous Pathology

Volumn 25, Issue 1, 1998, Pages 30-34

  Murphy, George F ^a,c   Katz, Sara ^b   Kligman, Albert M ^b  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c Jefferson Alumni Hall ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD1 ANTIGEN; HLA DR ANTIGEN; RETINOIC ACID;

ADULT; ANTIGEN EXPRESSION; ARTICLE; CELL COUNT; CELL FUNCTION; CLINICAL ARTICLE; DENDRITIC CELL; DERMIS; EPIDERMIS; EPIDERMIS CELL; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNITY; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; LANGERHANS CELL; MALE; SKIN EPITHELIUM; SKIN INJURY; SUN EXPOSURE; TIME; TOPICAL DRUG ADMINISTRATION;

ADMINISTRATION, TOPICAL; ADULT; ANTIGENS, CD1; CELL COUNT; CHRONIC DISEASE; DENDRITIC CELLS; DERMATITIS, PHOTOTOXIC; FEMALE; HLA-DR ANTIGENS; HUMANS; IMMUNOHISTOCHEMISTRY; KERATOLYTIC AGENTS; LANGERHANS CELLS; MALE; MIDDLE AGED; SKIN; TRETINOIN;

EID: 0031964249     PISSN: 03036987     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0560.1998.tb01686.x     Document Type: Article

References (33)

1. Nishigori C, Yaroshi DB, Donawho C, Kripke ML. The immune system in ultraviolet carcinogenesis. J Invest Dermatol Symp Proc 1996: 1: 143.
2. Kripke ML. Immunological unresponsiveness induced by ultraviolet radiation. Immunol Rev 1984: 80: 87.
3. Cruz PD, Bergstresser PR. The influence of ultraviolet radiation and other physical and chemical agents on epidermal Langerhans cells. In: Schuler G, ed. Epidermal Langerhans Cells. Boca raton, FL: CRC Press, 1991: 253.
4. Simon JC, Tigelaar DH, Bergstresser PR, Edelbaum D, Cruz PD. Ultraviolet B radiation converts Langerhans cells from immunogenic to tolerogenic antigen-presenting cells. J Immunol 1991: 146: 485.
5. Vermeer M, Streilein JW. Ultraviolet B light-induced alterations in epidermal Langerhans cells are mediated in part by tumor necrosis factor-alpha. Photodermatol Photoimmunol Photomed 1990: 7: 258.
6. Cooper KD, Duraiswamy N, Hammerber C et al. Neutrophils, differentiated macrophages, and monocyte/ macrophage antigen presenting cells infiltrate murine epidermis after UV injury. J Invest Dermatol 1993: 101: 155.
7. Norval M, Gilmour JW, Simpson TJ. The effect of histamine receptor antagonists on immunosuppression induced by the cis-isomer of urocanic acid. Photodermatol Photoimmunol Photomed 1990: 7: 243.
8. Gilchrest BA, Murphy GF, Soter NA. Effect of chronologic aging and ultraviolet irradiation on Langerhans cells in human epidermis. J Invest Dermatol 1982: 79: 85.
9. Walsh LJ, Trinchieri G, Waldorf HA, Whitaker D, Murphy GF. Human dermal mast cells contain and release tumor necrosis factor-α which induces endothelial leukocyte adhesion molecule-1. Proc Natl Acad Sci USA 1991: 88: 4220.
10. Ioffreda MD, Whitaker D, Murphy GF. Mast cell degranulalion upregulales α6 integrins on epidermal Langerhans relis. J Invest Dermatol 1993: 101: 150.
11. Wille JJ, Kydonieus A. Abrogation of contact hypersensitivity in mice by topically-applied mast cell degranulating agents. J Invest Dermatol 1995: 104: 679.
12. Thiers BH, Maize JC, Spicer SS, Cantor AB. The effect of aging and chronic sun exposure on human Langerhans cell populations. J Invest Dermatol 1984: 82: 223.
13. Schwartz JL, Frim SR, Shklar G. RA can alter the distribution of ATPase-positive Langerhans cells in the hamster cheek pouch in association with DMBA application. Nutr Cancer 1985: 7: 77.
14. Halliday GM, Dickenson JL, Muller HK. Retinoic acid protects Langerhans cells from the effects of the tumour promotor 12-O-tetradecanoylphorbol 13-acetate. Immunology 1989: 67: 298.
15. Halliday GM, McKay DA. Topical retinoic acid inhibits changes in Langerhans cell density during carcinogenesis. In Vivo 1993: 7: 271.
16. Fernandez-Bussy RA, Schmitt D, Maudnit G, Thivolet J. Effects of aromatic retinoid (Ro 109359) on Langerhans cells in lichen planus. Arch Dermatol Res 1983: 275: 105.
17. Haftek M, Faure M, Schmitt D, Thivolet J. Langerhans cells in the skin from patients with psoriasis: quantitative and qualitative study of T6 and HLA-DR antigen-expressing cells and changes with aromatic retinoid administration. J Invest Dermatol 1983: 81: 10.
18. Rook AH, Jaworsky C, Nguyen T et al. Beneficial effect of low dose systemic retinoid in combination with topical tretinoin for the treatment and prophylaxis of premalignant and malignant skin lesions in renal transplant recipients. Transplantation 1995: 59: 714.
19. Meunier L, Bohjanen K, Voorhees JJ, Cooper KD. Retinoic acid up-regulales human Langerhans cell antigen presentation and surface expression of HLA-DR and C-D11C, a beta-2 integrin critically involved in T-cell activation. J Invest Dermatol 1994: 103: 775.
20. Bernard F, Demarchez M, Ortonne JP, Czerniewlski J. Sequence of morphological events during topical application of retinoic acid on the rhino mouse skin. Br J Dermatol 1991: 125: 419.
21. Hachisuka H, Uno H. Effects of retinoic acid on the epidermal Langerhans cells and beta-glucuronidase activity in macaque skin. Am J Dermatopathol 1987: 9: 316.
22. Schwartz E, Cruikshank FA, Mezick JA, Kligman LH. Topical all-trans retinoic acid stimulates collagen synthesis in vivo. J Invest Dermatol 1991: 96: 975.
23. Barnadas MA, Curell R, Moragas JM. Effect of topical tretinoin on epidermal Langerhans' cells in photodamaged skin. Int Dermatol 1995: 34: 580.
24. Griffiths CE, Kang S, Ellis CN et al. Two concentrations of topical tretinoin (retinoic acid) cause similar improvement of photoaging but different degrees of irritation. A double-blind, vehicle-controlled comparison of 0.1% and 0.025% tretinoin creams. Arch Dermatol 1995: 131: 1037.
25. Bedford PA, Knight SC. Effects of retinoids on dendritic cells may be dose-related (inhibitory at high doses, stimulatory at low doses). Clin Exp Immunol 1989: 75: 481.
26. Harrist TJ, Muhlbauer JE, Murphy GF, Mihm Jr MC, Bhan AK. T6 is superior to 1a (HIA-DR) as a marker for Langerhans cells and indeterminate cells in normal epidermis: a monoclonal antibody study. J Invest Dermatol 1983: 80: 100.
27. Tsambaos D, Orfanos CE. Ultrastructural evidence suggesting an immunomodulatory activity of oral retinoid. Its effect on dermal components in psoriasis. Br J Dermatol 1981: 104: 37.
28. Dunlop KJ, Halliday GM, Barnetson RS. All-trans retinoic acid induces functional maturation of epidermal Langerhans cells and protects their accessory function from ultraviolet radiation. Exp Dermatol 1994: 3: 204.
29. Reichrath J, Munssinger T, Kerber A et al. In-situ detection of retinoid-X receptor expression in normal and psoriatic human skin. Br J Dermatol 1995: 133: 168.
30. Rosenthal DS, Roop DR, Huff CA et al. Topical retinoids effect some but not all keratinocyte differentiation pathways. J Invest Dermatol 1990: 95: 510.
31. Nakajima H, Kizaki M, Sonoda A, Mori S, Harigaya K, Ikeda Y. Retinoids (all-trans and 9-cis retinoic acid) stimulate production of macrophage colony-stimulating factor and granulocyte-macrophage colony-stimulating factor by human bone marrow stromal cells. Blood 1994: 84: 4107.
32. Willis CM, Stephens CJ, Wilkinson JD. Differential effects of structurally unrelated chemical irritants on the density and morphology of epidermial CD1+ cells. J Invest Dermatol 1990: 95: 711.
33. Cotsarelis G, Sun T-T, Lavker RM. Label-retaining cells in the bulge area of pilo-sebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis. Cell 1989: 61: 1329.