The role of glyoxalase I in the detoxification of methylglyoxal and in the activation of the KefB K+ efflux system in Escherichia coli

Molecular Microbiology

Volumn 27, Issue 3, 1998, Pages 563-571

  MacLean, M J ^a   Ness, L S ^a   Ferguson, G P ^a   Booth, I R ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

LACTOYLGLUTATHIONE LYASE;

ARTICLE; CONTROLLED STUDY; DETOXIFICATION; ENZYME ACTIVITY; ESCHERICHIA COLI; NONHUMAN; POTASSIUM TRANSPORT; PRIORITY JOURNAL;

ANTIPORTERS; BACTERIAL PROTEINS; CLONING, MOLECULAR; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; GENES, BACTERIAL; GLUTATHIONE; LACTOYLGLUTATHIONE LYASE; POTASSIUM; POTASSIUM CHANNELS; POTASSIUM-HYDROGEN ANTIPORTERS; PYRUVALDEHYDE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA; PROKARYOTA;

EID: 0031963196     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.1998.00701.x     Document Type: Article

References (31)

1. Ackerman, R.S., Cozzarelli, N.R., and Epstein, W. (1974) Accumulation of toxic concentrations of methylglyoxal by wild-type Escherichia coli K12. J Bacteriol 119: 357-362.
2. Ausubel, F.M., Brent, R., Kingston, R.E., Moore, D.D., Seidman, J.G., Smith, J.A., et al. (1987, updated, 1993) Current Protocols in Molecular Biology. New York: John Wiley & Sons.
3. Booth, I.R., Jones, M.A., McLaggan, D., Nikolaev, Y., Ness, L., Wood, C.M., et al. (1996) Bacterial ion channels. In Handbook of Biological Physics. Konings, W.N., Kaback, H.R., and Lolkema, J.S. (eds). Amsterdam: Elsevier, pp. 693-730.
4. Cliffe, E.E., and Waley, S.G. (1961) The mechanism of the glyoxalase I reaction, and the effect of ophthalmic acid as an inhibitor. Biochem J 79: 475-482.
5. Clugston, S.L., Daub, E., Kinach, R., Miedema, D., Barnard, J.F.J., and Honek, J.F. (1997) Isolation and sequencing of a gene coding for glyoxalase I activity from Salmonella tymphimurium and comparison with other glyoxylase I sequences. Gene 186: 103-111.
6. Cooper, R.A., and Anderson, A. (1970) The formation and catabolism of methylglyoxal during glycolysis in Escherichia coli. FEBS Lett 11: 273-276.
7. Együd, L.G., and Szent-Györgyi, A. (1966) On the regulation of cell division. Proc Natl Acad Sci USA 56: 203-207.
8. Elmore, M.J., Lamb, A.J., Ritchie, G.Y., Douglas, R.M., Munro, A., Gajewska, A., et al. (1990) Activation of potassium efflux from Escherichia coli by glutathione metabolites. Mol Microbiol 4: 405-412.
9. Epstein, W., and Kim, B.S. (1971) Potassium transport in Escherichia coli K-12. J Bacteriol 108: 639-644.
10. Ferguson, G.P., Munro, A.W., Douglas, R.M., McLaggan, D., and Booth, I.R. (1993) Activation of potassium channels during metabolite detoxification in Escherichia coli. Mol Microbiol 9: 1-7.
11. Ferguson, G.P., McLaggan, D., and Booth, I.R. (1995) Potassium channel activation by glutathione-S-conjugates in Escherichia coli: protection against methylglyoxal is mediated by cytoplasmic acidification. Mol Microbiol 17: 1025-1033.
12. + uptake system Kdp sensitises cells of Escherichia coli to methylglyoxal. J Bacteriol 178: 3957-3961.
13. Ferguson, G.P., Nikolaev, Y., McLaggan, D., MacLean, M., and Booth, I.R. (1997) Survival during exposure to the electrophile reagent N-ethylmaleimide in Escherichia coli: role of KefB and KefC potassium channels. J Bacteriol 179: 1007-1012.
14. Freedberg, W.B., Kistler, W.S., and Lin, E.C.C. (1971) Lethal synthesis of methylglyoxal by Escherichia coli during unregulated glycerol metabolism. J Bacteriol 108: 137-144.
15. Hopper, D.J., and Cooper, R.A. (1971) The regulation of Escherichia coli methylglyoxal synthase: a new control site in glycolysis? FEBS Lett 13: 213-216.
16. Kim, N-S., Umezawa, Y., Ohmura, S., and Kato, S. (1993) Human glyoxalase I: cDNA, cloning, expression and sequence similarity to glyoxalase I from Pseudomonas putida. J Biol Chem 268: 11217-11221.
17. Kohara, Y., Akiyama, K., and Isono, K. (1987) The physical map of the whole Escherichia coli chromosome: application of a new strategy for rapid analysis and sorting of a large genomic library. Cell 50: 495-508.
18. Kushner, S.R., Nagaishi, H., Templin, A., and Clark, A.J. (1971) Genetic recombination in Escherichia coli: the role of exonuclease 1. Proc Natl Acad Sci USA 68: 824-827.
19. Lu, T., Creighton, D.J., Antoine, M., Fenselau, C., and Lovett, P.S. (1994) The gene encoding glyoxalase I from Pseudomonas putida: cloning, over-expression and sequence comparisons with human glyoxalase I. Gene 150: 93-96.
20. Misra, K., Banerjee, A.B., Ray, S., and Ray, M. (1995) Glyoxalase III from Escherichia coli: a single novel enzyme for the conversion of methylglyoxal into D-lactate without reduced glutathione. Biochem J 305: 999-1003.
21. Misra, K., Banerjee, A.B., Ray, S., and Ray, M. (1996) Reduction of methylglyoxal in Escherichia coli K12 by an aldehyde reductase and alcohol dehydrogenase. Mol Cell Biochem 156: 117-124.
22. Munro, A.W., Ritchie, G.Y., Lamb, A.J., Douglas, R.M., and Booth, I.R. (1991) The cloning and sequence of the gene for the glutathione-regulated potassium efflux system KefC of Escherichia coli. Mol Microbiol 5: 607-616.
23. Murata, K., Inoue, Y., Watanabi, K., Fukuda, Y., Saikusa, T., Shimosaka, M., et al. (1986) Metabolism of a-ketoaldehydes in yeasts: purification and characterization of glyoxalase II from Saccharomyces cerevisiae. Agric Biol Chem 50: 135-142.
24. Murata, K., Inoue, Y., Rhee, H.-I., and Kimura, A. (1989) 2-Oxoaldehyde metabolism in microorganisms. Can J Microbiol 35:423-431.
25. Racker, E. (1951) Spectrophotometric enzymatic methods for the determination of aldehydes and ketoaldehydes. Methods Enzymol 3: 293-296.
26. Rowland, G.G., Giffard, P.M., and Booth, I.R. (1984) Genetic studies on the phs locus of Escherichia coli, a mutation causing pleiotropic lesions in metabolism and pH homeostasis. FEBS Lett 173: 295-300.
27. Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd edn. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
28. Shin, M.J., Edinger, J.W., and Creighton, D.J. (1997) Diffusion-dependent kinetic properties of glyoxalase I and estimates of the steady state concentrations of glyoxalase-pathway intermediates in glycolyzing erythrocytes. Eur J Biochem 244: 852-857.
29. Stewart, G.S.A.B., Lubinsky-Mink, S., Jackson, C.G., Cassel, A., and Kuhn, J. (1986) pHG165: a pBR322 copy number derivative of pUC8 for cloning and expression. Plasmid 18: 172-181.
30. Tötemeyer, S., Booth, N.A., Nichols, W.W., Dunbar, B., and Booth, I.R. (1998) From famine to feast: the role of methylglyoxal production in Escherichia coli. Mol Microbiol 27: 553-562.
31. Uotila, L. (1973) Purification and characterization of S-2-hydroxyacylglutathione hydrolase glyoxalase II from human liver. Biochemistry 12: 3944-3951.