The central pattern generator for vomiting may exist in the reticular area dorsomedial to the retrofacial nucleus in dogs

Experimental Brain Research

Volumn 118, Issue 2, 1998, Pages 139-147

  Koga, Tomoshige ^a   Qu, Rui Yao ^a,b   Fukuda, Hiroyuki ^a  

^a KAWASAKI MEDICAL SCHOOL   (Japan)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Kainic acid; Retrofacial nucleus; Vomiting

Indexed keywords

KAINIC ACID;

ABDOMINAL WALL MUSCULATURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTONOMIC NERVE; CONTROLLED STUDY; DOG; FEMALE; MALE; MEDULLA OBLONGATA; MUSCLE CONTRACTION; NERVE CELL; NONHUMAN; PATTERN GENERATOR; PHRENIC NERVE; PRIORITY JOURNAL; RETICULAR FORMATION; RETROFACIAL NUCLEUS; SALIVATION; VAGUS NERVE STIMULATION; VOMITING;

ANIMALS; DECEREBRATE STATE; DOGS; ELECTRIC STIMULATION; FEMALE; INJECTIONS; KAINIC ACID; MALE; MEDULLA OBLONGATA; RETICULAR FORMATION; SALIVA; SECRETORY RATE; VOMITING;

EID: 0031962819     PISSN: 00144819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002210050265     Document Type: Article

References (44)

1. Andrews PLR, Hawthorn J (1988) The neurophysiology of vomiting. Baillieres Clin Gastroenterol 21:141-168
2. Barnes JH (1984) The physiology and pharmacology of emesis. Mol Aspects Med 7:397-508
3. Berger AJ (1979) Distribution of carotid sinus nerve afferent fibers to solitary tract nuclei of the cat using transganglionic transport of horseradish peroxidase. Neurosci Lett 14:153-158
4. Bianchi AL, Grélot L (1989) Converse motor output of inspiratory bulbospinal premotoneurones during vomiting. Neurosci Lett 104:298-302
5. Borison HL, Wang SC (1949) Functional localization of central coordinating mechanism for emesis in cat. J Neurophysiol 12:305-313
6. Borison HL, Wang SC (1953) Physiology and pharmacology of vomiting. Pharmacol Rev 5:193-230
7. Davis CJ, Harding RK, Leslie RA, Andrews PLR (1986) The organization of vomiting as a protective reflex: a commentary on the first day's discussions. In: Davis CJ, Lake-Bakaar GV, Grahame-Smith DG (eds) Nausea and vomiting: mechanisms and treatment. Springer, Berlin Heidelberg New York, pp 65-75
8. Davis RO, Edwards MW Jr (1973) Distribution of carotid body chemoreceptor afferents in the medulla of the cat. Brain Res 64:451-454
9. Duffin J, Douse MA (1993) Bötzinger expiratory neurones inhibit propriobulbar decrementing inspiratory neurones. Neuroreport 4:1215-1218
10. Ezure K (1990) Synaptic connections between medullary respiratory neurons and considerations on the genesis of respiratory rhythm. Prog Neurobiol 35:429-450
11. Fukuda H, Koga T (1991) The Bötzinger complex as the pattern generator for retching and vomiting in the dog. Neurosci Res 12:471-485
12. Fukuda H, Koga T (1992) Non-respiratory neurons in the Bötzinger complex exhibiting appropriate tiring patterns to generate the emetic act in dogs. Neurosci Res 14:180-194
13. Fukuda H, Koga T (1993) Hypercapnia and hypoxia which develop during retching participate in the transition from retching to expulsion in dogs. Neurosci Res 17:205-215
14. Fukuda H, Koga T (1995a) Activation of peripheral and/or central chemoreceptors changes retching activities of Bötzinger complex neurons and induces expulsion in decerebrate doss. Neurosci Res 23:171-183
15. Fukuda H, Koga T (1995b) Stimulation of glossopharyngeal and laryngeal nerve afferents induces expulsion only when it is applied during retching in paralyzed decerebrate dogs. Neurosci Lett 193:117-120
16. Fukuda H, Koga T (1997) Neuronal gagging activity patterns may be generated by neurons in the reticular area dorsomedial to the retrofacial nucleus in dogs. Exp Brain Res 113:394-401
17. Furukawa N, Okada H (1994) Canine salivary secretion from the submaxillary glands before and during retching. Am J Physiol 267:G810-G817
18. Grélot L, Bianchi AL (1992) Activities of cranial and spinal respiratory-related motoneurons during vomiting. In: Bianchi AL, Grélot L, Miller AD, King GL (eds) Mechanisms and control of emesis. John Libbey Eurotext, France, pp 29-39
19. Grélot L, Barillot JC, Bianchi AL (1990) Activity of respiratory-related oropharyngeal and laryngeal motoneurones during fictive vomiting in the decerebrate cat. Brain Res 513:101-105
20. Hukuhara T, Okada H, Yamagami M (1957) On the behavior of the respiratory muscles during vomiting. Acta Med Okayama 11:117-125
21. Ikeda M, Yamanaka Y (1967) Electrical stimulation study on localization of the vomiting center (in Japanese). J Physiol Soc Jpn 29:129-130
22. Iwase Y, Ikeda M, Yoshikawa H (1967) Induction of emesis by electrical stimulation of the surface of the medulla oblongata. J Physiol Soc Jpn 29:712-713
23. Jiang C, Lipski J (1990) Extensive monosynaptic inhibition of ventral respiratory group neurons by augmenting neurons in the Bötzinger complex in the cat. Exp Brain Res 81:639-648
24. Koga T (1991) Discharge patterns of bulbar respiratory neurons during retching and vomiting in decerebrate dogs. Jpn J Physiol 41:233-249
25. Koga T, Fukuda H (1990) Characteristic behavior of the respiratory muscles, esophagus, and external anal and urethral sphincters during straining, retching, and vomiting in the decerebrate dog. Jpn J Physiol 40:789-807
26. Koga T, Fukuda H (1992) Neurons in the nucleus of the solitary tract mediating inputs from emetic vagal afferents and the area postrema to the pattern generator for the emetic act in dogs. Neurosci Res 14:166-179
27. Koga T, Fukuda H (1994a) Bulbospinal augmenting inspiratory neurons may participate in contractions of the diaphragm during vomiting in decerebrate dogs. Neurosci Lett 180:257-260
28. Koga T, Fukuda H (1994b) Descending pathways from the pattern generator of emesis to motor neurons of the diaphragm and abdominal muscles in decerebrate dogs. Jpn J Physiol [Suppl] 44:S107
29. Kuru M, Sugihara S (1955) Contributions to the knowledge of bulbar autonomie centres. II. Relationship of the vagal nuclei to the gastrojejunal motility. Jpn J Physiol 5:21-36
30. Lang IM, Marvig J, Sarna SK, Condon RE (1986) Gastrointestinal myoelectric correlates of vomiting in the dog. Am J Physiol 251:G830-G838
31. Lang IM, Marvig J, Sarna SK (1988) Comparison of gastrointestinal responses to CCK-8 and association with vomiting. Am J Physiol 254:G254-G263
32. Lang IM, Sarna SK, Dodds W (1993) Pharyngeal, esophageal, and proximal gastric responses associated with vomiting. Am J Physiol 265:G963-G972
33. Miller AD, Ruggiero DA (1994) Emetic reflex arc revealed by expression of the immediate-early gene c-fos in the cat. J Neurosci 14:871-888
34. Miller AD, Wilson VJ (1983) "Vomiting center" reanalyzed: an electrical stimulation study. Brain Res 270:154-158
35. Miller AD, Ezure K, Suzuki I (1985) Control of abdominal muscles by brainstem respiratory neurons in the cat. J Neurophysiol 54:155-167
36. Miller AD, Tan LK, Suzuki I (1987) Control of abdominal and expiratory intercostal muscle activity during vomiting: role of ventral respiratory group expiratory neurons. J Neurophysiol 57:1854-1866
37. Miller AD, Nonaka S, Jakus J (1994) Brain areas essential or nonessential for emesis. Brain Res 647:255-264
38. Miller AD, Nonaka S, Siniaia MS, Jakus J (1995) Multifunctional ventral respiratory group: bulbospinal expiratory neurons play a role in pudendal discharge during vomiting. J Auton Nerv Syst 54:253-260
39. Monges H, Salducci J, Naudy B (1978) Dissociation between the electrical activity of the diaphragmatic dome and crura muscular fibers during esophageal distension, vomiting and eructation. An electromyographic study in the dog. J Physiol (Paris) 74:541-554
40. Panneton WM, Loewy AD (1980) Projections of the carotid sinus nerve to the nucleus of the solitary tract in the cat. Brain Res 191:239-244
41. St John WM (1990) Neurogenesis, control and functional significance of gasping. J Appl Physiol 68:1305-1315
42. Tan LK, Miller AD (1986) Innervation of periesophageal region of cat's diaphragm: implication for studies of control of vomiting. Neurosci Lett 68:339-344
43. Wang SC, Borison HL (1951) The vomiting centre: its destruction by radon implantation in dog medulla oblongata. Am J Physiol 164:520-526
44. Wang SC, Borison HL (1952) A new concept of organization of the central emetic mechanism: recent studies on the sites of action of apomorphine, copper sulfate and cardiac glycosides. Gastroenterology 22:1-12