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Volumn 133, Issue 1, 1998, Pages 94-100

Effect of pentoxifylline in severe sepsis: Results of a randomized, double-blind, placebo-controlled study

Author keywords

[No Author keywords available]

Indexed keywords

PENTOXIFYLLINE;

EID: 0031962714     PISSN: 00040010     EISSN: None     Source Type: Journal    
DOI: 10.1001/archsurg.133.1.94     Document Type: Article
Times cited : (130)

References (41)
  • 1
    • 0022257240 scopus 로고
    • SCCM's new horizons conference on sepsis and septic shock
    • Ayres SM. SCCM's new horizons conference on sepsis and septic shock. Crit Care Med. 1985;13:864-866.
    • (1985) Crit Care Med , vol.13 , pp. 864-866
    • Ayres, S.M.1
  • 2
    • 0025234981 scopus 로고
    • Tumor necrosis factor in the pathophysiology of infection and sepsis
    • Fong Y, Lowry SF. Tumor necrosis factor in the pathophysiology of infection and sepsis. Clin Immunol Immunopathol. 1990;55:157-170.
    • (1990) Clin Immunol Immunopathol , vol.55 , pp. 157-170
    • Fong, Y.1    Lowry, S.F.2
  • 3
    • 0029067708 scopus 로고
    • Strategies for blocking the systemic effects of cytokines in the sepsis syndrome
    • Christman JW, Holden EP, Blackwell TS. Strategies for blocking the systemic effects of cytokines in the sepsis syndrome. Crit Care Med. 1995;23:955-963.
    • (1995) Crit Care Med , vol.23 , pp. 955-963
    • Christman, J.W.1    Holden, E.P.2    Blackwell, T.S.3
  • 4
    • 0029835023 scopus 로고    scopus 로고
    • Intersept: An international, multicenter, placebo-controlled trial of monoclonal antibody to human tumor necrosis factor-α in patients with sepsis
    • Cohen J, Carlet J. Intersept: an international, multicenter, placebo-controlled trial of monoclonal antibody to human tumor necrosis factor-α in patients with sepsis. Crit Care Med. 1996;24:1431-1440.
    • (1996) Crit Care Med , vol.24 , pp. 1431-1440
    • Cohen, J.1    Carlet, J.2
  • 5
    • 0029900294 scopus 로고    scopus 로고
    • Treatment of septic shock with the tumor necrosis receptor: Fc fusion protein
    • Fisher CJ, Agosti JM, Opal SM, et al. Treatment of septic shock with the tumor necrosis receptor: Fc fusion protein. N Engl J Med. 1996;334:1697-1702.
    • (1996) N Engl J Med , vol.334 , pp. 1697-1702
    • Fisher, C.J.1    Agosti, J.M.2    Opal, S.M.3
  • 6
    • 0027411960 scopus 로고
    • Monoclonal antibodies to tumor necrosis factor in sepsis: Help or harm?
    • Bone RC. Monoclonal antibodies to tumor necrosis factor in sepsis: help or harm? Crit Care Med. 1993;21:311-312.
    • (1993) Crit Care Med , vol.21 , pp. 311-312
    • Bone, R.C.1
  • 7
    • 0023912576 scopus 로고
    • Inhibition of the inflammatory action of interleukin-1 and tumor necrosis factor alpha on neutrophil function by pentoxifylline
    • Sullivan GW, Carper HT, Novick WJ, Mandell GL. Inhibition of the inflammatory action of interleukin-1 and tumor necrosis factor alpha on neutrophil function by pentoxifylline. Infect Immun. 1988;56:1722-1729.
    • (1988) Infect Immun , vol.56 , pp. 1722-1729
    • Sullivan, G.W.1    Carper, H.T.2    Novick, W.J.3    Mandell, G.L.4
  • 8
    • 0021960666 scopus 로고
    • Clinical pharmacology of pentoxifylline with special reference to its hemorrheologic effect for the treatment of intermittent claudication
    • Dettelbach HR, Aviado DM. Clinical pharmacology of pentoxifylline with special reference to its hemorrheologic effect for the treatment of intermittent claudication. J Clin Pharmacol. 1985;25:8-26.
    • (1985) J Clin Pharmacol , vol.25 , pp. 8-26
    • Dettelbach, H.R.1    Aviado, D.M.2
  • 10
    • 0025059497 scopus 로고
    • Pentoxifylline inhibits lipopolysaccharideinduced serum tumor necrosis factor and mortality
    • Noel P, Nelson S, Bokulie R, et al. Pentoxifylline inhibits lipopolysaccharideinduced serum tumor necrosis factor and mortality. Life Sci. 1990;47:1023-1029.
    • (1990) Life Sci , vol.47 , pp. 1023-1029
    • Noel, P.1    Nelson, S.2    Bokulie, R.3
  • 12
    • 0022374931 scopus 로고
    • Pentoxifylline treatment in patients with occlusive peripheral arterial disease: Circulatory changes and effects on prostaglandin synthesis
    • Poggesi L, Scarti L, Boddi M, Masotti G, Serneri GGN. Pentoxifylline treatment in patients with occlusive peripheral arterial disease: circulatory changes and effects on prostaglandin synthesis. Angiology. 1985;36:628-637.
    • (1985) Angiology , vol.36 , pp. 628-637
    • Poggesi, L.1    Scarti, L.2    Boddi, M.3    Masotti, G.4    Serneri, G.G.N.5
  • 13
    • 0025162668 scopus 로고
    • Attenuation of tumor necrosis factorinduced endothelial cell cytotoxicity and neutrophil chemoluminescence
    • Zheng J, Crowly J, Chang JH, et al. Attenuation of tumor necrosis factorinduced endothelial cell cytotoxicity and neutrophil chemoluminescence. Am Rev Respir Dis. 1990;142:1073-1078.
    • (1990) Am Rev Respir Dis , vol.142 , pp. 1073-1078
    • Zheng, J.1    Crowly, J.2    Chang, J.H.3
  • 14
    • 0022349212 scopus 로고
    • Pentoxifylline in the treatment of experimental peritonitis in rats
    • Chalkiadakis GE, Kostakis A, Karayannacos PE, et al. Pentoxifylline in the treatment of experimental peritonitis in rats. Arch Surg. 1985;120:1141-1144.
    • (1985) Arch Surg , vol.120 , pp. 1141-1144
    • Chalkiadakis, G.E.1    Kostakis, A.2    Karayannacos, P.E.3
  • 15
    • 0024467641 scopus 로고
    • The effects of aminophylline and pentoxifylline on multiple organ damage after Escherichia coli sepsis
    • Harada H, Ishizaka A, Yonemaru M, et al. The effects of aminophylline and pentoxifylline on multiple organ damage after Escherichia coli sepsis. Am Rev Respir Dis. 1989;140:974-980.
    • (1989) Am Rev Respir Dis , vol.140 , pp. 974-980
    • Harada, H.1    Ishizaka, A.2    Yonemaru, M.3
  • 16
    • 0024327280 scopus 로고
    • Pentoxifylline prevents tumor necrosis factor-induced lung injury
    • Lilly CM, Sandhu JS, Ishizaka A, et al. Pentoxifylline prevents tumor necrosis factor-induced lung injury. Am Rev Respir Dis. 1989;139:1358-1361.
    • (1989) Am Rev Respir Dis , vol.139 , pp. 1358-1361
    • Lilly, C.M.1    Sandhu, J.S.2    Ishizaka, A.3
  • 17
    • 0025276776 scopus 로고
    • Pentoxifylline increases survival in murine endotoxin shock and decreases formation of tumor necrosis factor
    • Schade UF. Pentoxifylline increases survival in murine endotoxin shock and decreases formation of tumor necrosis factor. Circ Shock. 1990;31:171-181.
    • (1990) Circ Shock , vol.31 , pp. 171-181
    • Schade, U.F.1
  • 18
    • 0030006971 scopus 로고    scopus 로고
    • Influence of long-term continuous intravenous administration of pentoxifylline on endothelial-related coagulation in critically ill patients
    • Boldt J, Müller M, Heyn S, Welters I, Hempelmann G. Influence of long-term continuous intravenous administration of pentoxifylline on endothelial-related coagulation in critically ill patients. Crit Care Med. 1996;24:940-946.
    • (1996) Crit Care Med , vol.24 , pp. 940-946
    • Boldt, J.1    Müller, M.2    Heyn, S.3    Welters, I.4    Hempelmann, G.5
  • 19
    • 0027456529 scopus 로고
    • Pilot study of cardiopulmonary risk from pentoxifylline in adult respiratory distress syndrome
    • Montravers P, Fagon JY, Gilber C, Blanchet F, Novara A, Chastre J. Pilot study of cardiopulmonary risk from pentoxifylline in adult respiratory distress syndrome. Chest. 1993;103:1017-1022.
    • (1993) Chest , vol.103 , pp. 1017-1022
    • Montravers, P.1    Fagon, J.Y.2    Gilber, C.3    Blanchet, F.4    Novara, A.5    Chastre, J.6
  • 20
    • 9044224023 scopus 로고    scopus 로고
    • Effects of pentoxifylline on circulating cytokine concentrations and hemodynamics in patients with septic shock: Results from a double-blind, randomized, placebo-controlled study
    • Zeni F, Pain P, Vindimian M, et al. Effects of pentoxifylline on circulating cytokine concentrations and hemodynamics in patients with septic shock: results from a double-blind, randomized, placebo-controlled study. Crit Care Med. 1996;24: 207-214.
    • (1996) Crit Care Med , vol.24 , pp. 207-214
    • Zeni, F.1    Pain, P.2    Vindimian, M.3
  • 23
    • 0022256529 scopus 로고
    • APACHE II: A severity of disease classification system
    • Knaus WA, Draper EA, Wagner DP, et al. APACHE II: a severity of disease classification system. Crit Care Med. 1985;13:818-829.
    • (1985) Crit Care Med. , vol.13 , pp. 818-829
    • Knaus, W.A.1    Draper, E.A.2    Wagner, D.P.3
  • 25
    • 0022972464 scopus 로고
    • A highly sensitive cell line, WEHI 164 subclone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes
    • Espevik T, Nissen-Meyer J. A highly sensitive cell line, WEHI 164 subclone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes. J Immunol Methods. 1986;95:99-105.
    • (1986) J Immunol Methods , vol.95 , pp. 99-105
    • Espevik, T.1    Nissen-Meyer, J.2
  • 27
    • 0019223424 scopus 로고
    • Determination of oxpentifylline and a metabolite, 1-(5′hydroxyhexyl)-3-7-dimethylxanthine, by gas-liquid chromatography using a nitrogen-selective detector
    • Bryce TA, Burrows JL. Determination of oxpentifylline and a metabolite, 1-(5′hydroxyhexyl)-3-7-dimethylxanthine, by gas-liquid chromatography using a nitrogen-selective detector. J Chromatogr. 1980;181:355-361.
    • (1980) J Chromatogr , vol.181 , pp. 355-361
    • Bryce, T.A.1    Burrows, J.L.2
  • 28
    • 0029986796 scopus 로고    scopus 로고
    • Potential strategies for inflammatory mediator manipulation: Retrospect and prospect
    • Fisher CJ, Zheng Y. Potential strategies for inflammatory mediator manipulation: retrospect and prospect. World J Surg. 1996;20:447-453.
    • (1996) World J Surg , vol.20 , pp. 447-453
    • Fisher, C.J.1    Zheng, Y.2
  • 29
    • 0028850811 scopus 로고
    • Round table conference on clinical trials for the treatment of sepsis
    • Sibbald WJ, Vincent JL. Round table conference on clinical trials for the treatment of sepsis. Grit Care Med. 1995;23:394-399.
    • (1995) Grit Care Med , vol.23 , pp. 394-399
    • Sibbald, W.J.1    Vincent, J.L.2
  • 30
    • 0026876699 scopus 로고
    • Definitions for sepsis and organ failure and guidelines for the use of innovative therapy in sepsis
    • Bone RC, Sprung CL, Sibbald WJ. Definitions for sepsis and organ failure and guidelines for the use of innovative therapy in sepsis. Crit Care Med. 1992;20: 724-726.
    • (1992) Crit Care Med , vol.20 , pp. 724-726
    • Bone, R.C.1    Sprung, C.L.2    Sibbald, W.J.3
  • 31
    • 0029922017 scopus 로고    scopus 로고
    • A genomic polymorphism within tumor necrosis factor locus influences plasma tumor necrosis factor-a concentrations and outcome of patients with severe sepsis
    • Stüber F, Petersen M, Bokelmann F, Schade FU. A genomic polymorphism within tumor necrosis factor locus influences plasma tumor necrosis factor-a concentrations and outcome of patients with severe sepsis. Crit Care Med. 1996;24:381-384.
    • (1996) Crit Care Med , vol.24 , pp. 381-384
    • Stüber, F.1    Petersen, M.2    Bokelmann, F.3    Schade, F.U.4
  • 32
    • 0025903905 scopus 로고
    • Tumor necrosis factor alpha mediates lethal activity of killed gram-negative and gram-positive bacteria in D-galactosamine-treated mice
    • Freudenberg MA, Galanos C. Tumor necrosis factor alpha mediates lethal activity of killed gram-negative and gram-positive bacteria in D-galactosamine-treated mice. Infect Immun. 1991;59:2110-2115.
    • (1991) Infect Immun , vol.59 , pp. 2110-2115
    • Freudenberg, M.A.1    Galanos, C.2
  • 33
    • 0026069467 scopus 로고
    • Early post-treatment with pentoxifylline or dibutryl cAMP attenuates Escherichia coli-induced acute lung injury in guinea pigs
    • Hoffmann H, Hatherill JR, Crowley J, et al. Early post-treatment with pentoxifylline or dibutryl cAMP attenuates Escherichia coli-induced acute lung injury in guinea pigs. Am Rev Respir Dis. 1991;143:289-293.
    • (1991) Am Rev Respir Dis , vol.143 , pp. 289-293
    • Hoffmann, H.1    Hatherill, J.R.2    Crowley, J.3
  • 34
    • 0023893831 scopus 로고
    • Detection of circulating tumor necrosis factor after endotoxin administration
    • Michie HR, Manogue KR, Spriggs DR, et al. Detection of circulating tumor necrosis factor after endotoxin administration. N Engl J Med. 1988;318:1481-1486.
    • (1988) N Engl J Med , vol.318 , pp. 1481-1486
    • Michie, H.R.1    Manogue, K.R.2    Spriggs, D.R.3
  • 36
    • 0025284616 scopus 로고
    • The biological characteristics of cytokines and their implications in surgical injury
    • Fong Y, Moldawer LL, Shires GT, Lowry SF. The biological characteristics of cytokines and their implications in surgical injury. Surg Gynecol Obstet. 1990;170: 363-378.
    • (1990) Surg Gynecol Obstet , vol.170 , pp. 363-378
    • Fong, Y.1    Moldawer, L.L.2    Shires, G.T.3    Lowry, S.F.4
  • 37
    • 0028343142 scopus 로고
    • Current prospects for the treatment of clinical sepsis
    • Suffredini AF. Current prospects for the treatment of clinical sepsis. Crit Care Med. 1994;20(suppl):S12-S18.
    • (1994) Crit Care Med. , vol.20 , Issue.SUPPL.
    • Suffredini, A.F.1
  • 38
    • 0027943614 scopus 로고
    • Beneficial cardiopulmonary effects of pentoxifylline in experimental sepsis are lost once septic shock is established
    • Ridings PC, Windsor ACJ, Sugerman HJ, et al. Beneficial cardiopulmonary effects of pentoxifylline in experimental sepsis are lost once septic shock is established. Arch Surg. 1994;129:1144-1152.
    • (1994) Arch Surg , vol.129 , pp. 1144-1152
    • Ridings, P.C.1    Windsor, A.C.J.2    Sugerman, H.J.3
  • 39
    • 0028354622 scopus 로고
    • The effects of oral pentoxifylline on the cytokine release syndrome during inductive OKT3
    • DeVault GA, Kohan DE, Nelson EW, Holman JM. The effects of oral pentoxifylline on the cytokine release syndrome during inductive OKT3. Transplantation. 1994;57:532-540.
    • (1994) Transplantation , vol.57 , pp. 532-540
    • DeVault, G.A.1    Kohan, D.E.2    Nelson, E.W.3    Holman, J.M.4
  • 40
    • 0028895086 scopus 로고
    • Pentoxifylline attenuates pulmonary macromolecular leakage after intestinal ischemia-reperfusion
    • Carter MB, Wilson MA, Wead WB, Garrison RN. Pentoxifylline attenuates pulmonary macromolecular leakage after intestinal ischemia-reperfusion. Arch Surg. 1995;130:1337-1344.
    • (1995) Arch Surg , vol.130 , pp. 1337-1344
    • Carter, M.B.1    Wilson, M.A.2    Wead, W.B.3    Garrison, R.N.4
  • 41
    • 0027319851 scopus 로고
    • Pentoxifylline restores cardiac output and tissue perfusion after trauma-hemorrhage and decreases susceptibility to sepsis
    • Wang P, Ba ZF, Zhou M, Tait SM, Chaudry IH. Pentoxifylline restores cardiac output and tissue perfusion after trauma-hemorrhage and decreases susceptibility to sepsis. Surgery. 1993;114:352-359.
    • (1993) Surgery , vol.114 , pp. 352-359
    • Wang, P.1    Ba, Z.F.2    Zhou, M.3    Tait, S.M.4    Chaudry, I.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.