Does total antioxidant status relate to outcome in very preterm infants?

Clinical Science

Volumn 94, Issue 2, 1998, Pages 197-201

  Drury, Josephine A ^a   Nycyk, Julie A ^a   Baines, Malcolm ^a   Cooke, Richard W I ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Chronic lung disease; Intraventricular haemorrhage; Lipid peroxidation; Malondialdehyde; Oxygen derived free radicals; Preterm infant; Retinopathy of prematurity; Total antioxidant status

Indexed keywords

ANTIOXIDANT; BILIRUBIN; FREE RADICAL; MALONALDEHYDE; URATE;

ANTIOXIDANT ACTIVITY; ARTICLE; BILIRUBIN BLOOD LEVEL; BLOOD LEVEL; BRAIN HEMORRHAGE; CHRONIC LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; LIPID PEROXIDATION; NEWBORN; NEWBORN DEATH; PREMATURITY; PRIORITY JOURNAL; RETROLENTAL FIBROPLASIA; TREATMENT OUTCOME; URIC ACID BLOOD LEVEL;

EID: 0031962386     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/cs0940197     Document Type: Article

References (27)

1. Fardy C, Silverman M. Antioxidants in neonatal lung disease. Arch Dis Child 1995; 73: F112-17.
2. Saugstad O. Oxygen toxicity in the neonatal period. Acta Paediatr Scand 1990; 79: 881-92.
3. Kelly FJ. Free radical disorders of preterm infants. Br Med Bull 1993; 49: 668-78.
4. Rosenfeld W, Concepcion L, Evans H. Serial trypsin inhibitory capacity and caeruloplasmin levels in prematures at risk of BPD. Am Rev Respir Dis 1986; 134: 1229-32.
5. Lindeman JHN. Limited protection against iron induced lipid peroxidation by cord blood plasma. Free Rad Res Commun 1992; 16: 285-94.
6. Gopinathan V, Miller NJ, Milner AD, Rice-Evans CA. Bilirubin and ascorbate antioxidant activity in neonatal plasma. FEBS Lett 1994; 349: 197-200.
7. Moyer WT. Vitamin E levels in term and premature newborn infants. Pediatrics 1950; 6: 893-6.
8. Lindeman JHN, van Zoeren-Grobben D, Schrijver J, Speek AJ, Poorthuis BHJM, Berger HM. The total free radical trapping ability of cord blood plasma in preterm and term babies. Pediatr Res 1989; 26: 20-4.
9. Scott PH, Berger HM, Keward C, Scott P, Wharton BA. Effect of gestational age and intrauterine nutrition on plasma transferrin and iron in the newborn. Arch Dis Child 1975; 50: 796-8.
10. Stocker R, Yamamoto Y, McDonagh A. Bilirubin as an antioxidant of possible physiological importance. Science (Washington DC) 1987; 235: 1043-6.
11. Stocker R, Glazer AN, Ames BN. Antioxidant activity of albumin-bound bilirubin. Proc Natl Acad Sci 1987; 84: 5918-22.
12. Fauchere J, Meier-Gibbons F, Koerner F, Bossi E. Retinopathy of prematurity and bilirubin - no clinical evidence for a beneficial role of bilirubin as a physiological antioxidant. Eur J Pediatr 1994; 153: 358-62.
13. Gaton D, Gold J, Axer-Segel A. Evaluation of bilirubin as a possible protective factor in the prevention of retinopathy of prematurity. Br J Ophthalmol 1991; 75: 532-4.
14. Heyman E, Ohlsson A, Girschek P. Retinopathy of prematurity and bilirubin. N Engl J Med 1989; 320: 256.
15. Boynton B, Boynton C. Retinopathy of prematurity and bilirubin. N Engl J Med 1989; 321: 193-4.
16. Hegyi T, Goldie E, Hiatt M. The protective role of bilirubin in oxygen-radical diseases of the preterm infant. J Perinatol 1994; 14: 296-300.
17. Ehrenkranz RA, Mercurio MR. Bronchopulmonary dysplasia. In: Sinclair JC, Bracken MB, eds. Effective care of the newborn infant. Oxford: Oxford University Press, 1992: 399-424.
18. Chiswick ML, Johnson M, Woodhall C. Protective effect of vitamin E against intraventricular haemorrhage in premature babies. Br Med J 1983; 287: 81-4.
19. Sinha S, Davies J, Toner N. Vitamin E supplementation reduces frequency of periventricular haemorrhage in very premature babies. Lancet 1987; 1: 466-70.
20. Shenai JP, Kennedy KA, Chytil F, Stahlman MT. Clinical trial of vitamin A supplementation in infants susceptible to bronchopulmonary dysplasia. J Pediatr 1987; 111: 269-77.
21. Papagaroufalis C, Cairis M, Pantazatou E, Megreli CH, Xanthou M. A trial of vitamin A supplementation for the prevention of bronchopulmonary dysplasia in very low birthweight infants. Pediatr Res 1988; 23: 518A.
22. Inder TE, Graham P, Sanderson K, Taylor BJ. Lipid peroxidation as a measure of oxygen free radical damage in the very low birthweight infant. Arch Dis Child 1994; 70: F107-11.
23. Schlenzig JS, Bervoets K, von Loewenich V, Bohles H. Urinary malondialdehyde concentration in preterm neonates: is there a relationship to disease entities of neonatal intensive care. Acta Paediatr 1993; 82: 202-5.
24. Drury JA, Nycyk JA, Cooke RWI. Comparison of urinary and plasma malondialdehyde in preterm infants. Clin Chim Acta 1997; 263: 177-85.
25. Miller NJ, Rice-Evans C, Davies MJ, Gopinathan V, Milner A. A novel method for measuring antioxidant capacity and its application to monitoring the antioxidant status in premature neonates. Clin Sci 1993; 84: 407-12.
26. Gutteridge JMC. Free-radical damage to lipids, amino acids, carbohydrates and nucleic acids determined by thiobarbituric acid reactivity. Int J Biochem 1982; 14: 649-53.
27. Rice-Evans C, Miller NJ. Total antioxidant status in plasma and body fluids. Methods Enzymol 1994; 234: 279-93.