Streptavidin in antibody pretargeting. Comparison of a recombinant streptavidin with two streptavidin mutant proteins and two commercially available streptavidin proteins

Bioconjugate Chemistry

Volumn 9, Issue 1, 1998, Pages 100-107

  Wilbur, D Scott ^a   Stayton, Patrick S ^a   To, Richard ^a   Buhler, Kent R ^b   Klumb, Lisa A ^a   Hamlin, Donald K ^a   Stray, James E ^b   Vessella, Robert L ^b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT PROTEINS; SIZE EXCLUSION CHROMATOGRAPHY; SPECTRUM ANALYSIS; SULFUR COMPOUNDS;

COMMERCIAL SOURCES; ELECTROSPRAYS; IN-VITRO; IN-VIVO; MASS-SPECTRAL ANALYSIS; MUTANT PROTEINS; SDS-PAGE; STREPTAVIDIN; VITRO CHARACTERIZATION; WILD TYPES;

AMINO ACIDS;

ANIMALIA; MUS MUSCULUS;

EID: 0031962102     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc970152s     Document Type: Article

References (51)

1. Hnatowich, D. J., Virzi, F., and Rusckowski, M. (1987) Investigations of Avidin and Biotin for Imaging Applications. J. Nucl. Med. 28, 1294-1302.
2. Goodwin, D. A. (1995) Tumor Pretargeting: Almost the Bottom Line. J. Nucl. Med. 36, 876-879.
3. Paganelli, G., Malcovati, M., and Fazio, F. (1991) Monoclonal Antibody pretargetting techniques for tumour localization: the avidin-biotin system. Nucl. Med. Commun. 12, 211-234.
4. 90Y Radioimmunotherapy in a Mouse Xenograft Model. J. Immunother. 16, 158.
5. del Rosario, R. B., and Wahl, R. L. (1993) Biotinylated Iodo-Polylysine for Pretargeted Radiation Delivery. J. Nucl. Med. 34, 1147-1151.
6. Jeong, J. M., Kinuya, S., Paik, C. H., Saga, T., Sood, V. K., Carrasquillo, J. A., Neumann, R. D., and Reynolds, J. C. (1994) Application of High Affinity Binding Concept to Radiolabel Avidin with Tc-99m Labeled Biotin and the Effect of pI on Biodistribution. Nucl. Med. Biol. 21, 935-940.
7. Oehr, P., Westermann, J., and Biersack, H. J. (1988) Streptavidin and Biotin as Potential Tumor Imaging Agents J. Nucl. Med. 29, 728-729.
8. Pimm, M. V., Fells, H. F., Perkins, A. C., and Baldwin, R. W. (1988) Iodine-131 and indium-111 labelled avidin and Streptavidin for pre-targetted immunoscintigraphy with biotinylated anti-tumour monoclonal antibody. Nucl. Med Commun. 9, 931-941.
9. 67GA Deferoxamineacetyl-Cysteinylbiotin. Drug Metab. Dispos. 23, 1362-1367.
10. Shoup, T. M., Fischman, A. J., Jaywook, S., Babich, J. W., Strauss, H. W., and Elmaleh, D. R. (1994) Synthesis of Fluorine-18-Labeled Biotin Derivatives: Biodistribution and Infection Localization. J. Nucl. Med. 35, 1685-1690.
11. Yao, Z., Zhang, M., Kobayashi, H., Sakahara, H., Nakada, H., Yamashina, I., and Konishi, J. (1995) Improved Targeting of Radiolabeled Streptavidin in Tumors Pretargeted with Biotinylated Monoclonal Antibodies through an Avidin Chase. J. Nucl. Med. 36, 837-841.
12. Khawli, L. A., Alauddin, M. M., Miller, G. K., and Epstein, A. L. (1993) Improved Immunotargeting of Tumors with Biotinylated Monoclonal Antibodies and Radiolabeled Streptavidin. Antibody, Immunoconjugates, Radiopharm. 6, 13-27.
13. Kassis, A. I., Jones, P. L., Matalka, K. Z., and Adelstein, S. J. (1996) Antibody-Dependent Signal Amplification in Tumor Xenografts after Pretreatment with Biotinylated Monoclonal Antibody and Avidin or Streptavidin. J. Nucl. Med. 37, 343-352.
14. Wilbur, D. S., Hamlin, D. K., Vessella, R. L., Stray, J., Buhler, K. R., Stayton, P., Klumb, L., Pathare, P. M., and Weerawarna, S. A. (1996) Antibody Fragments in Tumor Pretargeting. Evaluation of Biotinylated Fab'Co-localization with Recombinant Streptavidin and Avidin. Bioconjugate Chem. 7, 689-702.
15. Green, N. M. (1975) Avidin. Adv. Protein Chem. 29, 85-133.
16. Green, N. M. (1990) Avidin and Streptavidin. Methods Enzymol. 184, 51-67.
17. Schechter, B., Silberman, R., Arnon, R., and Wilchek, M. (1990) Tissue distribution of avidin and steptavidin injected to mice. Effect of avidin, carbohydrate, Streptavidin truncation and exogenous biotin. Eur. J. Biochem. 189, 327-331.
18. Rosebrough, S. F. (1993) Pharmacokinetics and Biodistribution of Radiolabeled Avidin, Streptavidin and Biotin. Nucl. Med. Biol. 20, 663-668.
19. Rosebrough, S. F., and Hartley, D. F. (1996) Biochemical Modification of Streptavidin and Avidin: In Vitro and In Vivo Analysis. J. Nucl. Med. 37, 1380-1384.
20. 2 Fragments of an Anti-Tumour Antibody. Br. J. Cancer 71, 18-24.
21. Chilkoti, A., Tan, P. H., and Stayton, P. S. (1995) Site-directed mutagenesis studies of the high-affinity streptavidin-biotin complex: contributions of tyrosine residues 79, 108, and 120. Proc. Natl. Acad. Sci. U.S.A. 92, 1754-1758.
22. Wilchek, M., and Bayer, E. A. (1990) Introduction to Avidin-Biotin Technology. Methods Enzymol. 184, 5-45.
23. Diamandis, E. P., and Christopoulos, T. K. (1991) The Biotin-(Strept)Avidin System: Principles and Applications in Biotechnology. Clin. Chem. 37, 625-636.
24. Wilchek, M., and Bayer, E. A. (1988) The Avidin-Biotin Complex in Bioanalytical Applications. Anal. Biochem. 171, 1-32.
25. del Rosario, R. B., and Wahl, R. L. (1990) Disulfide Bond-targeted Radiolabeling: Tumor Specificity of a Streptavidin-biotinylated Monoclonal Antibody Complex. Cancer Res. 50, 804-808.
26. 111In-Labeled Biotin. Antibody, Immunoconjugates, Radiopharm. 6, 97-109.
27. Paganelli, G., Pervez, S., Siccardi, A. G., Rowlinson, G., Deleide, G., Chiolerio, F., Malcovati, M., Scassellati, G. A., and Epenetos, A. A. (1990) Intraperitoneal Radio-Localization of Tumors Pre-Targeted by Biotinylated Monoclonal Antibodies. Int. J. Cancer 45, 1184-1189.
28. Saga, T., Weinstein, J. N., Jeong, J. M., Heya, T., Lee, J. T., Le, N., Paik, C. H., Sung, C., and Neumann, R. D. (1994) Two-Step Targeting of Experimental Lung Metastases with Biotinylated Antibody and Radiolabeled Streptavidin. Cancer Res. 54, 2160-2165.
29. Chilkoti, A., Schwartz, B. L., Smith, R. D., Long, C. J., and Stayton, P. S. (1995) Engineered Chimeric Streptavidin Tetramers as Novel Tools for Bioseparations and Drug Delivery. Bio/Technology 13, 1198-1204.
30. Wilbur, D. S., Hadley, S. W., Hylarides, M. D., Abrams, P. G., Beaumier, P. A., Morgan, A. C., Reno, J. M., and Fritzberg, A. R. (1989) Development of a Stable Radioiodinating Reagent to Label Monoclonal Antibodies for Radiotherapy of Cancer. J. Nucl. Med. 30, 216-226.
31. Fritzberg, A. R., Beaumier, P. L., Bottino, B. J., and Reno, J. M. (1994) Approaches to improved antibody-and peptide-mediated targeting for imaging and therapy of cancer. J. Controlled Release 28, 167-173.
32. Sano, T., Pandori, M. W., Chen, X., Smith, C. L., and Cantor, C. R. (1995) Recombinant Core Streptavidins. A Minimum-Sized Core Streptavidin Has Enhanced Structural Stability and Higher Accessibility to Biotinylated Macromolecules. J. Biol. Chem. 270, 28204-28209.
33. Gitlin, G., Bayer, E. A., and Wilchek, M. (1989) Studies on the Biotin-Binding Sites of Avidin and Streptavidin. Tyrosine residues are involved in the binding site. Biochem. J. 269, 527-530.
34. Gitlin, G., Khait, I., Bayer, E. A., Wilchek, M., and Muszkat, K. A. (1989) Studies on the Biotin-Binding Sites of Avidin and Streptavidin. A Chemically Induced Dynamic Nuclear Polarization Investigation of the Status of Tyrosine Residues. Biochem. J. 259, 493-498.
35. Hiller, Y., Bayer, E. A., and Wilchek, M. (1991) Studies on the Biotin-Binding Site of Avidin. Biochem. J. 278, 573-585.
36. Savage, M. D., Mattson, G., Desai, S., Nielander, G. W., Morgensen, S., and Conklin, E. J. (1992) Avidin-Biotin Chemistry: A Handbook, Pierce Chemical Co., Rockford, IL.
37. Morag, E., Bayer, E. A., and Wilchek, M. (1996) Reversibility of Biotin-Binding by Selective Modification of Tyrosine in Avidin. Biochem. J. 316, 193-199.
38. Rusckowski, M., Fogarasi, M., Virzi, F., and Hnatowich, D. J. (1995) Influence of endogenous biotin on the biodistribution of labelled biotin derivatives in mice. Nucl. Med. Commun. 16, 38-46.
39. Ngai, W. M., Reilly, R. M., Polihronis, J., and Shptiz, B. (1995) In Vitro and In Vivo Evaluation of Streptavidin Immunoconjugates of the Second Generation TAG-72 Monoclonal Antibody CC49. Nucl. Med. Biol. 22, 77-86.
40. Schechter, B., Arnon, R., Colas, C., Burakova, T., and Wilcheck, M. (1995) Renal accumulation of streptavidin: Potential use for targeted therapy of the kidney. Kidney Int. 47, 1327-1335.
41. Zhang, M., Sakahara, H., Yao, Z., Saga, T., Nakamoto, Y., Sato, N., Nakada, H., Yamashina, I., and Konishi, J. (1997) Intravenous Avidin Chase Improved Localization of Radiolabeled Streptavidin in Intraperitoneal Xenograft Pretargeted with Biotinylated Antibody. Nucl. Med. Biol. 24, 61-64.
42. Bayer, E. A., Ben-Hur, H., Gitlin, G., and Wilchek, M. (1986) An improved method for the single-step purification of streptavidin. J. Biochem. Biophys. Methods 13, 103-112.
43. Argarana, C. E., Kuntz, I. D., Birken, S., Axel, R., and Cantor, C. R. (1986) Molecular cloning and nucleotide sequence of the streptavidin gene. Nucleic Acids Res. 14, 1871-1882.
44. Pahler, A., Hendrickson, W. A., Kolks, M. A. G., Argarana, C. E., and Cantor, C. R. (1987) Characterization and Crystallization of Core Streptavidin. J. Biol. Chem. 262, 13933-13937.
45. Bayer, E. A., Hen-Hur, H., Hiller, Y., and Wilchek, M. (1989) Postsecretory modifications of streptavidin. Biochem. J. 259, 369-376.
46. Dittmer, J., Dittmer, A., Bruna, R. D., and Kasche, V. (1989) A native, affinity-based protein blot for the analysis of streptavidin heterogeneity: Consequences for the specificity of streptavidin mediated binding assays. Electrophoresis 10, 762-765.
47. 3H]Biotin Bound to Different Avidin Analogues. J. Drug Targeting 3, 159-165.
48. Pharmacia (1982) Isoelectric Focusing: Principles and Methods, Ljungföretagen AB, Örebro, Uppsala, Sweden.
49. Reznik, G. O., Vajda, S., Smith, C. L., Cantor, C. R., and Sano, T. (1996) Streptavidins with intersubunit crosslinks have enhanced stability. Nat. Biotechnol. 14, 1007-1011.
50. Sano, T., Smith, C. L., and Cantor, C. R. (1993) A Streptavidin Mutant Containing a Cysteine Stretch That Facilitates Production of a Variety of Specific Streptavidin Conjugates. Bio/Technology 11, 201-206.
51. Wilbur, D. S., Hamlin, D. K., Pathare, P. M., and Weerawarna, S. A. (1997) Biotin Reagents for Antibody Pretargeting. Synthesis, Radioiodination and In Vitro Evaluation of Water Soluble, Biotinidase Resistant Biotin Derivatives. Bioconjugate Chem. 8, 572-584.