Potassium-induced release of endogenous morphine from rat brain slices

Journal of Neurochemistry

Volumn 70, Issue 1, 1998, Pages 147-152

  Guarna, M ^a   Neri, C ^b   Petrioli, F ^a   Bianchi, E ^a  

^a UNIVERSITY OF SIENA   (Italy)

^b UNIVERSITY OF VERONA   (Italy)

Author keywords

Endogenous morphine; Gas chromatography mass spectrometry; In vitro release; Membrane depolarization

Indexed keywords

MORPHINE; NALORPHINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; DRUG BRAIN LEVEL; GAS CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MORPHINE ADDICTION; NEUROMODULATION; NEUROTRANSMISSION; NONHUMAN; POTASSIUM TRANSPORT; PRIORITY JOURNAL; RAT;

ANIMALIA; MAMMALIA;

EID: 0031961830     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.70010147.x     Document Type: Article

References (32)

1. Bianchi E., Alessandrini C., Guarna M., and Tagliamonte A. (1993) Endogenous codeine and morphine are stored in specific brain neurons. Brain Res. 627, 210-215.
2. Bianchi E., Guarna M., and Tagliamonte A. (1994) Immunocytochemical localization of endogenous codeine and morphine. Adv. Neuroimmunol. 4, 83-92.
3. Birks R. I. and McIntosh F. C. (1961) Acetylcholine metabolism of sympathetic ganglion. Can. J. Biochem. Physiol. 39, 787-827.
4. Cardinale G., Donnerer J., Finck A. D., Kantrowitz J. D., Oka K., and Spector S. (1987) Morphine and codeine are endogenous components of human cerebrospinal fluid. Life Sci. 40, 301-306.
5. Don-Liang L., Hwang L., and Chau-Yang C. (1995) Storage temperature effect on the stability of morphine and codeine in urine. J. Anal. Toxicol. 19, 275-280.
6. Donnerer J., Oka K., Brossi A., Rice K. C., and Spector S. (1986) Presence and formation of codeine and morphine in the rat. Proc. Natl. Acad. Sci. USA 83, 4566-4567.
7. Donnerer J., Cardinale G., Coffey J., Lisek C. A., Jardine I., and Spector S. (1987) Chemical characterization and regulation of endogenous morphine and codeine in the rat. J. Pharmacol. Exp. Ther. 242, 583-587.
8. Epple A., Navarro I., Horak P., and Spector S. (1993) Endogenous morphine and codeine release by the chromaffin cells of the eel. Life Sci. 52, 117-121.
9. Felby S., Christensen H., and Lund A. (1974) Morphine concentration in blood and organs in case of fatal poisoning. J. Forensic Sci. 3, 77-81.
10. Gintzler A. R., Levy A., and Spector S. (1976) Antibodies as a means of isolating and characterizing biologically active substances: presence of a non-peptide, morphine-like compound in the central nervous system. Proc. Natl. Acad. Sci. USA 73, 2132-2136.
11. Gintzler A. R., Gershon M. D., and Spector S. (1978) A nonpeptide morphine-like compound: immunocytochemical localization in the mouse brain. Science 199, 447-448.
12. Goldstein A., Barrett R. W., James I. F., Lowney L. I., Weits C. J., Knipmeyer L. L., and Rapaport H. (1985) Morphine and other opiates from beef brain and adrenals. Proc. Natl. Acad. Sci. USA 82, 5203-5207.
13. Hazum E., Sabatka J. J., Chang K. J., Findlay J. W. A., and Cuatrecasa P. (1981) Morphine in cow and human milk: could dietary morphine constitute a ligand for specific morphine (μ) receptors? Science 213, 1010-1012.
14. Horak P., Haberman F., and Specter S. (1993) Endogenous morphine and codeine in mice - effect on muramyl dipeptide. Life Sci. 52, 255-260.
15. Killian A. K., Schuster C. R., House J. T., Shell S., Connors V. A., and Waener B. H. (1981) A non-peptide morphine-like compound from brain. Life Sci. 28, 811-817.
16. Knapp D. R. (1979) Drugs, in Handbook of Analytical Derivatization Reactions, pp. 621-627. Wiley, New York.
17. Kodaira H. and Spector S. (1988) Transformation of thebaine to oripavine, codeine and morphine by rat liver, kidney and brain microsomes. Proc. Natl. Acad. Sci. USA 85, 1267-1271.
18. Lee C. S. and Spector S. (1991) Changes of endogenous morphine and codeine in the fasting rat. J. Pharmacol. Exp. Ther. 257, 647-650.
19. Liu Y., Bilfinger T. V., and Stefano G. B. (1997) A rapid and sensitive quantitation method of endogenous morphine in human plasma. Life Sci. 60, 237-243.
20. Lubli G., Neri C., Chiminazzo S., Bonizzato L., and Mango M. (1990) Solid phase extraction of whole blood samples for general unknown investigations, in Proceedings of the 27th International Meeting of the International Association of Forensic Toxicologists, pp. 258-274. International Association of Forensic Toxicologists, Perth, Australia.
21. Matsubara K., Fukushima S., Akane H., Kobayashi S., and Shiono H. (1992) Increased urinary morphine, codeine and tetrahydropapaveroline in parkinsonian patients undergoing 1-3,3-dihydrophenylalanine therapy; a possible biosynthetic pathway of morphine from 1-3,4-dihydroxyphenylalanine in humans. J. Pharmacol. Exp. Ther. 260, 974-978.
22. Molina P. E., Hashiguchi Y., Meijerink W. J. H. J., Naukam R. J., Boxer R., and Abumrad N. N. (1995) Modulation of endogenous opiate production: effect of fasting. Biochem. Biophys. Res. Commun. 207, 312-317.
23. Oka K., Kantrowitz J. D., and Spector S. (1985) Isolation of morphine from toad skin. Proc. Natl. Acad. Sci. USA 82, 1852-1854.
24. Osborne H., Hollt V., and Herz A. (1978a) Potassium induced release of enkephalin from rat striatal slices. Eur. J. Pharmacol. 48, 219-221.
25. Osborne H., Hollt V., and Herz A. (1978b) Subcellular distribution of enkephalin and endogenous opioid activity in rat brain. Life Sci. 22, 611-618.
26. Pacak K., Palkovits M., Kvetnansky R., Yadid G., Kopin I. J., and Goldstein D. S. (1996) Effect of various stressors on in vivo norepinephrine release in the hypothalamic paraventricular nucleus and on the pituitary-adrenocortical axis. Ann. NY Acad. Sci. 771, 115-130.
27. Pfleger K., Maurer H. H., and Weber A. (1992) Mass Spectral and GC Data of Drugs, Poisons, Pesticides, Pollutants and Their Metabolites, p. 1985. WHC, Weinheim.
28. + stimulated release of methionine-enkephalin from slices of rat corpus striatum. Brain Res. 189, 483-493.
29. Stefano G. B., Digenis A., Spector S., Leung M. K., Bilfinger T. V., Makman M. H., Scharrer B., and Abumrad N. N. (1993) Opiate-like substances in an invertebrate. An opiate receptor on invertebrate and human immunocyte, and a role in immunosuppression. Proc. Natl. Acad. Sci. USA 90, 11099-11103.
30. Tagliamonte A., Guarna M., and Bianchi E. (1995) Endogenous morphine and codeine as possible physiological ligands of μ-opiate receptors, in Drug Addiction and Related Clinical Problems (Maremmani I. and Tagliamonte A., eds). pp. 27-35. Springer-Verlag, Vienna.
31. Weitz C., Lowney L. I., Faull K. F., Feister G., and Goldstein A. (1986) Morphine and codeine from mammalian brain. Proc. Natl. Acad. Sci. USA 83, 9784-9788.
32. Weitz C. J., Faull K., and Goldstein A. (1987) Synthesis of the skeleton of the morphine molecule by mammalian liver. Nature 330, 674-677.