-
1
-
-
0015919581
-
Molecular and catalytic properties of cytosolic acetoacetyl coenzyme A thiolase from avian liver
-
1 Clinkenbeard KD, Sugiyama T, Moss J, Reed WD, Lane MD. Molecular and catalytic properties of cytosolic acetoacetyl coenzyme A thiolase from avian liver. J Biol Chem 1973 ; 248: 2275–2284. MEDLINE
-
(1973)
J Biol Chem
, vol.248
, pp. 2275-2284
-
-
Clinkenbeard, KD1
Sugiyama, T2
Moss, J3
Reed, WD4
Lane, MD5
-
2
-
-
0001139449
-
Cytoplasmic 3‐hydroxy‐3‐methylglutaryl coenzyme A synthase from liver
-
2 Clinkenbeard KD, Sugiyama T, Reed WD, Lane MD. Cytoplasmic 3‐hydroxy‐3‐methylglutaryl coenzyme A synthase from liver. J Biol Chem 1975 ; 250: 3124–3135. MEDLINE
-
(1975)
J Biol Chem
, vol.250
, pp. 3124-3135
-
-
Clinkenbeard, KD1
Sugiyama, T2
Reed, WD3
Lane, MD4
-
4
-
-
0016861491
-
Molecular and catalytic properties of mitochondrial (ketogenic) 3‐hydroxy‐3‐methylglutaryl coenzyme A synthase of liver
-
4 Reed WD, Clinkenbeard KD, Lane MD. Molecular and catalytic properties of mitochondrial (ketogenic) 3‐hydroxy‐3‐methylglutaryl coenzyme A synthase of liver. J Biol Chem 1975 ; 250: 3117–3123. MEDLINE
-
(1975)
J Biol Chem
, vol.250
, pp. 3117-3123
-
-
Reed, WD1
Clinkenbeard, KD2
Lane, MD3
-
5
-
-
0025120211
-
Regulation of the mevalonate pathway
-
5 Goldstein JL, Brown MS. Regulation of the mevalonate pathway. Nature 1990 ; 343: 425–430. MEDLINE
-
(1990)
Nature
, vol.343
, pp. 425-430
-
-
Goldstein, JL1
Brown, MS2
-
6
-
-
0022970291
-
Cytoplasmic 3‐hydroxy‐3‐methylglutaryl coenzyme A synthase from the hamster
-
6 Gil G, Goldstein JL, Slaughter CA, Brown MS. Cytoplasmic 3‐hydroxy‐3‐methylglutaryl coenzyme A synthase from the hamster. J Biol Chem 1986 ; 261: 3710–3716. MEDLINE
-
(1986)
J Biol Chem
, vol.261
, pp. 3710-3716
-
-
Gil, G1
Goldstein, JL2
Slaughter, CA3
Brown, MS4
-
7
-
-
0028225462
-
SREBP‐1, a membrane‐bound transcription factor released by sterol‐regulated proteolysis
-
7 Wang X, Sato R, Brown MS, Hua X, Goldstein JL. SREBP‐1, a membrane‐bound transcription factor released by sterol‐regulated proteolysis. Cell 1994 ; 77: 53–62. MEDLINE
-
(1994)
Cell
, vol.77
, pp. 53-62
-
-
Wang, X1
Sato, R2
Brown, MS3
Hua, X4
Goldstein, JL5
-
8
-
-
0029797604
-
Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP‐1a
-
8 Shimano H, Horton JD, Hammer RE, Shimomura I, Brown MS, Goldstein JL. Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP‐1a. J Clin Invest 1996 ; 98: 1575–1584. MEDLINE
-
(1996)
J Clin Invest
, vol.98
, pp. 1575-1584
-
-
Shimano, H1
Horton, JD2
Hammer, RE3
Shimomura, I4
Brown, MS5
Goldstein, JL6
-
9
-
-
0021716702
-
The regulation of acetoacetyl‐CoA synthetase activity by modulators of cholesterol synthesis in vivo and the utilization of acetoacetate for cholesterogenesis
-
9 Bergstrom JD, Wong GA, Edwards PA, Edmond J. The regulation of acetoacetyl‐CoA synthetase activity by modulators of cholesterol synthesis in vivo and the utilization of acetoacetate for cholesterogenesis. J Biol Chem 1984 ; 259: 14548–14553. MEDLINE
-
(1984)
J Biol Chem
, vol.259
, pp. 14548-14553
-
-
Bergstrom, JD1
Wong, GA2
Edwards, PA3
Edmond, J4
-
10
-
-
0028963963
-
A novel assay for cytosolic 3‐hydroxy‐3‐methylglutaryl‐coenzyme A synthase activity using reversed‐phase ion‐pair chromatography: demonstration that Lifibrol (K12.148) modulates the enzyme activity
-
10 Scharnagl H, März W, Schliack M, Löser R, Gross W. A novel assay for cytosolic 3‐hydroxy‐3‐methylglutaryl‐coenzyme A synthase activity using reversed‐phase ion‐pair chromatography: demonstration that Lifibrol (K12.148) modulates the enzyme activity. J Lipid Res 1995 ; 36: 622–627. MEDLINE
-
(1995)
J Lipid Res
, vol.36
, pp. 622-627
-
-
Scharnagl, H1
März, W2
Schliack, M3
Löser, R4
Gross, W5
-
11
-
-
0018939225
-
Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl‐coenzyme A reductase and cholesterol‐lowering agent
-
11 Alberts AW, Chen J, Kuron G, Hunt V, Huff J, Hoffman C, Rothrock J, et al. Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl‐coenzyme A reductase and cholesterol‐lowering agent. Proc Natl Acad Sci U S A 1980 ; 77: 3957–3961. MEDLINE
-
(1980)
Proc Natl Acad Sci U S A
, vol.77
, pp. 3957-3961
-
-
Alberts, AW1
Chen, J2
Kuron, G3
Hunt, V4
Huff, J5
Hoffman, C6
Rothrock, J7
-
13
-
-
0022545008
-
The effects of BM 15.766, an inhibitor of D7‐dehydrocholesterol Δ7‐reductase, on cholesterol biosynthesis in primary rat hepatocytes
-
13 Aufenanger J, Pill J, Schmidt FH, Stegmeier K. The effects of BM 15.766, an inhibitor of D 7 ‐dehydrocholesterol Δ 7 ‐reductase, on cholesterol biosynthesis in primary rat hepatocytes. Biochem Pharmacol 1986 ; 35: 911–916. MEDLINE
-
(1986)
Biochem Pharmacol
, vol.35
, pp. 911-916
-
-
Aufenanger, J1
Pill, J2
Schmidt, FH3
Stegmeier, K4
-
14
-
-
0028200779
-
The effect of increased hepatic sitosterol on the regulation of 3‐hydroxy‐3‐methylglutaryl‐coenzyme A reductase and cholesterol 7α‐hydroxylase in the rat and sitosterolemic homozygotes
-
14 Shefer S, Salen G, Bullock J, Nguyen LB, Ness GC, Vhao Z, Belamarich PF, et al. The effect of increased hepatic sitosterol on the regulation of 3‐hydroxy‐3‐methylglutaryl‐coenzyme A reductase and cholesterol 7α‐hydroxylase in the rat and sitosterolemic homozygotes. Hepatology 1994 ; 20: 213–219. MEDLINE
-
(1994)
Hepatology
, vol.20
, pp. 213-219
-
-
Shefer, S1
Salen, G2
Bullock, J3
Nguyen, LB4
Ness, GC5
Vhao, Z6
Belamarich, PF7
-
15
-
-
0028884255
-
Markedly inhibited Δ7‐dehydrocholesterol Δ7‐reductase activity in liver microsomes from Smith‐Lemli‐Opitz homozygotes
-
15 Shefer S, Salen G, Batta AK, Honda A, Tint GS, Irons M, Elias ER, et al. Markedly inhibited Δ 7 ‐dehydrocholesterol Δ 7 ‐reductase activity in liver microsomes from Smith‐Lemli‐Opitz homozygotes. J Clin Invest 1995 ; 96: 1779–1785. MEDLINE
-
(1995)
J Clin Invest
, vol.96
, pp. 1779-1785
-
-
Shefer, S1
Salen, G2
Batta, AK3
Honda, A4
Tint, GS5
Irons, M6
Elias, ER7
-
16
-
-
0016861431
-
Intracellular localization of the 3‐hydroxy‐3‐methylglutaryl coenzyme A cycle enzymes in liver
-
16 Clinkenbeard KD, Reed WD, Mooney RA, Lane MD. Intracellular localization of the 3‐hydroxy‐3‐methylglutaryl coenzyme A cycle enzymes in liver. J Biol Chem 1975 ; 250: 3108–3116. MEDLINE
-
(1975)
J Biol Chem
, vol.250
, pp. 3108-3116
-
-
Clinkenbeard, KD1
Reed, WD2
Mooney, RA3
Lane, MD4
-
17
-
-
71849104860
-
Protein measurement with the Folin phenol reagent
-
17 Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951 ; 193: 265–275.
-
(1951)
J Biol Chem
, vol.193
, pp. 265-275
-
-
Lowry, OH1
Rosebrough, NJ2
Farr, AL3
Randall, RJ4
-
18
-
-
0019763101
-
Separation of S‐acyl‐CoA thioesters and related compounds by reversed‐phase ion‐pair chromatography
-
18 Baker FC, Schooley DA. Separation of S‐acyl‐CoA thioesters and related compounds by reversed‐phase ion‐pair chromatography. Methods Enzymol 1981 ; 72: 41–52. MEDLINE
-
(1981)
Methods Enzymol
, vol.72
, pp. 41-52
-
-
Baker, FC1
Schooley, DA2
-
19
-
-
0017357697
-
Regulation of cholesterol synthesis in rat adrenal gland through coordinate control of 3‐hydroxy‐3‐methylglutaryl coenzyme A synthase and reductase activities
-
19 Balasubramaniam S, Goldstein JL, Brown MS. Regulation of cholesterol synthesis in rat adrenal gland through coordinate control of 3‐hydroxy‐3‐methylglutaryl coenzyme A synthase and reductase activities. Proc Natl Acad Sci U S A 1977 ; 74: 1421–1425. MEDLINE
-
(1977)
Proc Natl Acad Sci U S A
, vol.74
, pp. 1421-1425
-
-
Balasubramaniam, S1
Goldstein, JL2
Brown, MS3
-
20
-
-
0025132445
-
A molecular defect in hepatic cholesterol biosynthesis in sitosterolemia with xanthomatosis
-
20 Nguyen LB, Shefer S, Salen G, Ness GC, Tint GS, Zaki FG, Rani I. A molecular defect in hepatic cholesterol biosynthesis in sitosterolemia with xanthomatosis. J Clin Invest 1990 ; 86: 923–931. MEDLINE
-
(1990)
J Clin Invest
, vol.86
, pp. 923-931
-
-
Nguyen, LB1
Shefer, S2
Salen, G3
Ness, GC4
Tint, GS5
Zaki, FG6
Rani, I7
-
21
-
-
0023409390
-
Molecular cloning and sequence of a cholesterol‐repressible enzyme related to prenyltransferase in the isoprene biosynthetic pathway
-
21 Clarke CF, Tanaka RD, Svenson K, Wamsley M, Fogelman AM, Edwards PA. Molecular cloning and sequence of a cholesterol‐repressible enzyme related to prenyltransferase in the isoprene biosynthetic pathway. Mol Cell Biol 1987 ; 7: 3138–3146. MEDLINE
-
(1987)
Mol Cell Biol
, vol.7
, pp. 3138-3146
-
-
Clarke, CF1
Tanaka, RD2
Svenson, K3
Wamsley, M4
Fogelman, AM5
Edwards, PA6
-
22
-
-
0342662303
-
Squalene synthetase activity in human fibroblasts: regulation via the low density lipoprotein receptor
-
22 Faust JR, Goldstein JL, Brown MS. Squalene synthetase activity in human fibroblasts: regulation via the low density lipoprotein receptor. Proc Natl Acad Sci U S A 1979 ; 76: 5018–5022. MEDLINE
-
(1979)
Proc Natl Acad Sci U S A
, vol.76
, pp. 5018-5022
-
-
Faust, JR1
Goldstein, JL2
Brown, MS3
-
23
-
-
0029783409
-
Regulation of the last two enzymatic reactions in cholesterol biosynthesis in rats: effects of BM 15.766, cholesterol, cholic acid, lovastatin, and their combinations
-
23 Honda A, Shefer S, Salen G, Xu G, Batta AK, Tint GS, Honda M, et al. Regulation of the last two enzymatic reactions in cholesterol biosynthesis in rats: effects of BM 15.766, cholesterol, cholic acid, lovastatin, and their combinations. Hepatology 1996 ; 24: 435–439. MEDLINE
-
(1996)
Hepatology
, vol.24
, pp. 435-439
-
-
Honda, A1
Shefer, S2
Salen, G3
Xu, G4
Batta, AK5
Tint, GS6
Honda, M7
-
24
-
-
0022995878
-
Regulation of rat liver 3‐hydroxy‐3‐methylglutaryl coenzyme A synthase and the chromosomal localization of the human gene
-
24 Mehrabian M, Callaway KA, Clarke CF, Tanaka RD, Greenspan M, Lusis AJ, Sparkes RS, et al. Regulation of rat liver 3‐hydroxy‐3‐methylglutaryl coenzyme A synthase and the chromosomal localization of the human gene. J Biol Chem 1986 ; 261: 16249–16255. MEDLINE
-
(1986)
J Biol Chem
, vol.261
, pp. 16249-16255
-
-
Mehrabian, M1
Callaway, KA2
Clarke, CF3
Tanaka, RD4
Greenspan, M5
Lusis, AJ6
Sparkes, RS7
-
25
-
-
0025279341
-
Inhibition of 3‐hydroxy‐3‐methylglutaryl coenzyme A synthase by antibiotic 1233A and other β‐lactones
-
25 Mayer RJ, Louis‐Flamberg P, Elliott JD, Fisher M, Leber J. Inhibition of 3‐hydroxy‐3‐methylglutaryl coenzyme A synthase by antibiotic 1233A and other β‐lactones. Biochem Biophys Res Commun 1990 ; 169: 610–616. MEDLINE
-
(1990)
Biochem Biophys Res Commun
, vol.169
, pp. 610-616
-
-
Mayer, RJ1
Louis‐Flamberg, P2
Elliott, JD3
Fisher, M4
Leber, J5
-
26
-
-
0020044109
-
Isolation and characterization of a mammalian cell mutant defective in 3‐hydroxy‐3‐methylglutaryl coenzyme A synthase
-
26 Schnitzer‐Polokoff R, von Gunten C, Logel J, Torget R, Sinensky M. Isolation and characterization of a mammalian cell mutant defective in 3‐hydroxy‐3‐methylglutaryl coenzyme A synthase. J Biol Chem 1982 ; 257: 472–476. MEDLINE
-
(1982)
J Biol Chem
, vol.257
, pp. 472-476
-
-
Schnitzer‐Polokoff, R1
von Gunten, C2
Logel, J3
Torget, R4
Sinensky, M5
-
27
-
-
0000716338
-
Mevinolin and colestipol stimulate receptor‐mediated clearance of low density lipoprotein from plasma in familial hypercholesterolemia heterozygotes
-
27 Bilheimer DW, Grundy SM, Brown MS, Goldstein JL. Mevinolin and colestipol stimulate receptor‐mediated clearance of low density lipoprotein from plasma in familial hypercholesterolemia heterozygotes. Proc Natl Acad Sci U S A 1983 ; 80: 4124–4128. MEDLINE
-
(1983)
Proc Natl Acad Sci U S A
, vol.80
, pp. 4124-4128
-
-
Bilheimer, DW1
Grundy, SM2
Brown, MS3
Goldstein, JL4
-
28
-
-
0028245959
-
Effect of squalene synthase inhibition on the expression of hepatic cholesterol biosynthetic enzymes, LDL receptor, and cholesterol 7α‐hydroxylase
-
28 Ness GC, Zhao Z, Keller RK. Effect of squalene synthase inhibition on the expression of hepatic cholesterol biosynthetic enzymes, LDL receptor, and cholesterol 7α‐hydroxylase. Arch Biochem Biophys 1994 ; 311: 277–285. MEDLINE
-
(1994)
Arch Biochem Biophys
, vol.311
, pp. 277-285
-
-
Ness, GC1
Zhao, Z2
Keller, RK3
-
29
-
-
0016366624
-
β‐Sitosterolemia and xanthomatosis
-
29 Bhattacharyya AK, Connor WE. β‐Sitosterolemia and xanthomatosis. J Clin Invest 1974 ; 53: 1033–1043. MEDLINE
-
(1974)
J Clin Invest
, vol.53
, pp. 1033-1043
-
-
Bhattacharyya, AK1
Connor, WE2
-
30
-
-
0026639212
-
Sitosterolemia
-
30 Salen G, Shefer S, Nguyen L, Ness GC, Tint GS, Shore V. Sitosterolemia. J Lipid Res 1992 ; 33: 945–955. MEDLINE
-
(1992)
J Lipid Res
, vol.33
, pp. 945-955
-
-
Salen, G1
Shefer, S2
Nguyen, L3
Ness, GC4
Tint, GS5
Shore, V6
-
31
-
-
0024587373
-
Effect of sitosterol on the rate‐limiting enzymes in cholesterol synthesis and degradation
-
31 Boberg KM, Åkerlund JE, Björkhem I. Effect of sitosterol on the rate‐limiting enzymes in cholesterol synthesis and degradation. Lipids 1989 ; 24: 9–12. MEDLINE
-
(1989)
Lipids
, vol.24
, pp. 9-12
-
-
Boberg, KM1
Åkerlund, JE2
Björkhem, I3
|