The activity of Drosophila Hairless is required in pupae but not in embryos to inhibit Notch signal transduction

Development Genes and Evolution

Volumn 208, Issue 1, 1998, Pages 19-27

  Schweisguth, François ^a,b   Lecourtois, Magalie ^a  

^a INSTITUT JACQUES MONOD   (France)

^b ECOLE NORMALE SUPÉRIEURE   (France)

Author keywords

Cell fate determination; Nervous system development; Signal transduction; Suppressor of hairless

Indexed keywords

GENE PRODUCT;

ALLELE; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DROSOPHILA; EMBRYO; EMBRYO DEVELOPMENT; FORELIMB; GENE ACTIVITY; GENE DELETION; GENE FUNCTION; IMAGINAL DISC; INSECT; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; REGULATOR GENE; SIGNAL TRANSDUCTION;

ANIMALS; CELL DIFFERENTIATION; DROSOPHILA; DROSOPHILA PROTEINS; EMBRYO, NONMAMMALIAN; FEMALE; INSECT PROTEINS; MALE; MEMBRANE PROTEINS; MUTATION; PUPA; RECEPTORS, NOTCH; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; STEM CELLS; TRANSCRIPTION FACTORS; WING;

EID: 0031960772     PISSN: 0949944X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004270050149     Document Type: Article

References (38)

1. Artavanis-Tsakonas S, Matsuno K, Fortini ME (1995) Notch signalling. Science 268: 225-232
2. Ashburner M (1982) The genetics of a small autosomal region of Drosophila melanogaster containing the structural gene for alcohol dehydrogenase. III. Hypomorphic mutations affecting the expression of Hairless. Genetics 101: 447-459
3. Bailey AM, Posakony JW (1995) Suppressor of Hairless directly activates transcription of Enhancer of split Complex genes in response to Notch receptor activity. Genes Dev 9: 2609-2622
4. Bang AG, Posakony JW (1992) The Drosophila gene Hairless encodes a novel basic protein that controls alternative cell fates in adult sensory organ development [published erratum appears in Genes Dev 1992 Nov;6(11):2233]. Genes Dev 6: 1752-1769
5. Bang AG, Hartenstein V, Posakony JW (1991) Hairless is required for the development of adult sensory organ precursor cells in Drosophila. Development 111: 89-104
6. Bang AG, Bailey AM, Posakony JW (1995) Hairless promotes stable commitment to the sensory organ precursor cell fate by negatively regulating the activity of the Notch signalling pathway. Dev Biol 172: 479-494
7. Brou C, Logeat F, Lecourtois M, Vandekerckhove J, Kourilsky P, Schweisguth F, Israël A (1994) Inhibition of the DNA-binding activity of Drosophila Suppressor of Hairless and of its human homolog, KBF2/RBP-Jκ, by direct protein-protein interaction with Drosophila Hairless. Genes Dev. 8: 2491-2503
8. Campos-Ortega JA (1993) Early neurogenesis in Drosophila melanogaster. In: Bate M, Martinez-Arias A (eds) The development of Drosophila melanogaster, vol 2. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp 1091-1129
9. Campos-Ortega JA, Hartenstein V (1985) The embryonic development of Drosophila inelanogaster. Springer, Berlin Heidelberg New York
10. Celis JF de, Bray S, Garcia-Bellido A (1997) Notch signalling regulates veinlet expression and establishes boundaries between veins and interveins in the Drosophila wing. Development 124: 1919-1928
11. Chou T-B, Perrimon N (1992) Use of a yeast site-specific recombinase to produce female germline chimeras in Drosophila. Genetics 131: 643-653
12. Chou T-B, Perrimon N (1996) The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster. Genetics 144: 1673-1679
13. Concha A de la, Dietrich U, Weigel D, Campos-Ortega JA (1988) Functional interactions of neurogenic genes of Drosophila melanogaster. Genetics 118: 499-508
14. Cubas P, Celis J-F de, Campuzano S, Modolell J (1991) Proneural clusters of achaete-scute expression and the generation of sensory organs in the Drosophila imaginal wing disc. Genes Dev 5: 996-1008
15. Fortini ME, Artavanis-Tsakonas S (1994) The Suppressor of Hairless protein participates in Notch receptor signalling. Cell 79: 273-282
16. Furukawa T, Kobayakawa Y, Tamura K, Kimura K-I, Kawaichi M, Tanimura T, Honjo T (1995) Suppressor of Hairless, the Drosophila homologue of RBP-Jk, transactivates the neurogenic gene E(spl)m8. Jpn J Genet 70: 505-524
17. Gho M, Lecourtois M, Géraud G, Posakony JW, Schweisguth F (1996) Subcellular localization of Suppressor of Hairless in Drosophila sense organ cells during Notch signalling. Development 122: 1673-1682
18. Heitzler P, Simpson P (1991) The choice of cell fate in the epidermis of Drosophila. Cell 64: 1083-1092
19. Heitzler P, Simpson P (1993) Altered Epidermal Growth Factor-like sequences provide evidence for a role of Notch as a receptor in cell fate decisions. Development 117: 1113-1123
20. Heitzler P, Bourouis M, Ruel L, Carteret C, Simpson P (1996) Genes of the Enhancer of split and achaete-scute complexes are required for a regulatory loop between Notch and Delta during lateral signalling in Drosophila. Development 122: 161-171
21. Huang F, Dambly-Chaudière C, Ghysen A (1991) The emergence of sense organs in the wing disc of Drosophila. Development 111: 1087-1095
22. Jennings B, Preiss A, Delidakis C, Bray S (1994) The Notch signalling pathway is required for Enhancer of split bHLH protein expression during neurogenesis in the Drosophila embryo. Development 120: 3537-3548
23. Kunish M, Haenlin M, Campos-Ortega J (1994) Lateral inhibition mediated by the Drosophila neurogenic gene Delta is enhanced by proneural proteins. Proc Natl Acad Sci USA 91: 10139-10143
24. Lecourtois M, Schweisguth F (1995) The neurogenic Suppressor of Hairless DNA-binding protein mediates the transcriptional activation of the Enhancer of split Complex genes triggered by Notch signalling. Genes Dev 9: 2598-2608
25. Lieber T, Kidd S, Alcamo E, Corbin V, Young MW (1993) Anti-neurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei. Genes Dev 7: 1949-1965
26. Lindsley DL, Zimm GG (1992) The genome of Drosophila melanogaster. Academic Press, San Diego
27. Maier D, Stumm G, Kuhn K, Preiss A (1992) Hairless, a Drosophila gene involved in neural development, encodes a novel, serine rich protein. Mech Dev 38: 143-156
28. O'Hare K, Murphy C, Lewis R, Rubi GM (1984) DNA sequence of the white locus of Drosophila melanogaster. J Mol Biol 180: 437-455
29. Schweisguth F (1995) Suppressor of Hairless is required for signal reception during lateral inhibition in the Drosophila pupal notum. Development 121: 1875-1884
30. Schweisguth F, Posakony JW (1992) Suppressor of Hairless, the Drosophila homolog of the mouse recombination signal-binding protein gene, controls sensory organ cell fates. Cell 69: 1199-1212
31. Schweisguth F, Posakony JW (1994) Antagonistic activities of Suppressor of Hairlessand Hairless control alternative cell fates in the Drosophilaadult epidermis. Development 120: 1433-1441
32. Schweisguth F, Gho M, Lecourtois M (1996) Control of cell fate choices by lateral signalling in the adult peripheral nervous system of Drosophila melanogaster. Dev Genet 1: 28-39
33. Seugnet L, Simpson P, Haenlin M (1997) Transcriptional regulation of Notch and Delta: requirement for neuroblast segregation in Drosophila. Development 124: 2015-2025
34. Skeath JB, Doe CQ (1996) The achaete-scute complex proneural genes contribute to neural precursor specification in the Drosophila CNS. Curr Biol 6: 1146-1152
35. Spana EP, Kopczynski C, Goodman CS, Doe CQ (1995) Asymmetric localization of numb autonomously determines sibling neuron identity in the Drosophila CNS. Development 121: 3489-3494
36. Struhl G, Fitzgerald K, Greenwald I (1993) Intrinsic activity of the Lin-12 and Notch intracellular domains in vivo. Cell 74: 331-345
37. Sturtevant MA, Bier E (1995) Analysis of the genetic hierarchy guiding wing vein development in Drosophila. Development 121: 785-801
38. Usui K, Kimura K (1993) Sequential emergence of the evenly spaced microchaetes on the notum of Drosophila. Roux's Arch Dev Biol 203: 151-158