The adsorption of cellulose ethers in aqueous suspensions of pyrantel pamoate: Effects on zeta potential and stability

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 45, Issue 2, 1998, Pages 181-188

  Duro, Roberto ^a   Alvarez, Carmen ^a   Martínez Pacheco, Ramón ^a   Gómez Amoza, José Luis ^a   Concheiro, Angel ^a   Souto, Consuelo ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

Aqueous suspensions; Hydroxypropylmethylcellulose; Interfacial adsorption; Physical stability; Pyrantel pamoate; Sodium carboxymethylcellulose; Zeta potential

Indexed keywords

CARBOXYMETHYLCELLULOSE; HYDROXYPROPYLMETHYLCELLULOSE; POLYMER; PYRANTEL EMBONATE;

ADSORPTION; AQUEOUS SOLUTION; ARTICLE; DRUG STABILITY; PHYSICAL CHEMISTRY; SUSPENSION; ZETA POTENTIAL;

CARBOXYMETHYLCELLULOSE; CHEMISTRY, PHARMACEUTICAL; DRUG STABILITY; METHYLCELLULOSE; PHARMACEUTIC AIDS; PYRANTEL PAMOATE;

EID: 0031960741     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0939-6411(97)00103-3     Document Type: Article

References (37)

1. C.M. Ofner, R.L. Schnaare, J.B. Schwartz, Oral aqueous suspensions, in: H.A. Lieberman, M.M. Rieger, G.S. Banker (Eds.), Pharmaceutical Dosage Forms. Disperse Systems, Vol. 2, Marcel Dekker, New York, 1988.
2. H. Napper, in: R.H. Ottewil, R.L. Rowell (Eds.), Polymeric-stabilization of Colloidal Dispersions, Academic Press, London, 1989.
3. Lochhead R.Y. Water soluble polymers Solution adsorption and interaction characteristics. Cosmet. Toilet. 107:1992;131-156.
4. Vaslin-Reimann S., Lafuma F., Audebert R. Reversible flocculation of silica suspensions by water-soluble polymers. Colloid Polym. Sci. 268:1990;476-483.
5. Law S.L. The microelectrophoretic properties of solid particles in the presence of nonionic water-soluble cellulose polymers. Pharm. Acta Helv. 59:1984;298-300.
6. Fritz A., Riehl J. Stabilization of suspensions by simultaneous addition of polymers and peptizing salts. Pharm. Ind. 51:1989;1150-1156.
7. Rawlins D.A., Kayes J.B. Steric stabilization of suspensions. Drug Dev. Ind. Pharm. 6:1980;427-440.
8. Tunçel T., Gürek F. Studies on formulation of loperamide hydrochloride suspensions. Eur. J. Pharm. Biopharm. 38:1992;82-88.
9. Duro R., Vázquez M.J., Martínez-Pacheco R., Gómez-Amoza J.L., Concheiro A., Souto C. Stabilization of mebendazole suspensions with cellulose ethers. Pharmazie. 48:1993;602-605.
10. Law S.L., Kayes J.B. Adsorption of non-ionic water-soluble cellulose polymers at the solid-water interface and their effect on suspension stability. Int. J. Pharm. 15:1983;251-260.
11. C.T. Rhodes, Disperse systems, in: G.S. Banker, C.T. Rhodes (Eds.), Drugs and the Pharmaceutical Sciences, Vol. 40, Modern Pharmaceutics, 2nd edn., Marcel Decker, New York, 1989.
12. Martindale, The Extra Pharmacopoeia, 30th edn., The Pharmaceutical Press, London, 1993.
13. I.S. Snyder, R.G. Finch, Anthelmintic drugs, in: C.R. Craig, R.E. Stitzel (Eds.), Modern Pharmacology, 2nd edn., Little, Brown, Boston, MA, 1986.
14. N.G. Stanley-Wood, Particle characterization by size, shape and surface for contacted particles, in: N.G. Stanley-Wood (Ed.), Enlargement and Compaction of Particulate Solids, Butterworths, London, 1983.
15. Rowe R.C. The molecular weight of methylcellulose used in pharmaceutical formulation. Int. J. Pharm. 11:1982;175-179.
16. G.V. Vinogradov, J.K. Malkin, Rheology of Polymers. Viscoelasticy and Flow of Polymers, Springer, Berlin, 1980.
17. Vázquez M.J., Gómez-Amoza J.L., Martinez-Pacheco R., Souto C., Concheiro A. Relationships between drug dissolution profile and gelling agent viscosity in tablets prepared with hydroxypropylmethylcellulose (HPMC) and sodium carboxymethylcellulose (NaCMC) mixtures. Drug Dev. Ind. Pharm. 21:1995;1859-1874.
18. Simha R. The influence of molecular flexibility on the intrinsic viscosity, sedimentation and diffusion of high polymers. J. Chem. Phys. 13:1945;188-195.
19. Kraëmer E.O. The determination of average molecular weights or particle sizes for polydispersed systems. J. Franklin Inst. 231:1941;1-21.
20. Chauveau C., Maillols H., Delonca H., Fortune R. Natrosol 250 H.I. Caractérisation du comportement rhéologique. Pharm. Acta Helv. 61:1986;292-297.
21. Mildwisky B.M. The rapid determination of carboxymethylcellulose and allied materials in detergents. Tenside Detergents. 10:1973;14-16.
22. D.J. Shaw, Introduction to Colloid and Surface Chemistry, 4th edn., Butterworth-Heinemann, London, 1980.
23. Nash R.A., Haeger B.E. Zeta potential in the development of pharmaceutical suspensions. J. Pharm. Sci. 55:1966;829-837.
24. Zetasizer 3, Instruction manual, Malvern Instruments.
25. A.B. Savage, Ethers, in: N.M. Bikales, L. Segal (Eds.), Cellulose and Cellulose Derivatives, Wiley-Interscience, New York, 1971.
26. C.H. Giles, T.H. MacEwan, S.N. Nakhwa, D. Smith, Studies in adsorption. Part XI. A system of classification of solution adsorption isotherms, and its use in diagnosis of adsorption mechanisms and in measurement of specific surface areas of solids, J. Chem. Soc. (1960) 3973-3993.
27. Perkell R., Ullman R. Adsorption of poly(dimethylsiloxanes) from solutions. J. Polymer Sci. 54:1961;127-148.
28. S. Ross, I.D. Morrison, Colloidal Systems and Interfaces, Wiley-Interscience, New York, 1988.
29. Kellaway I.W., Najib N.M. The adsorption of hydrophilic polymers at the polystyrene-water interface. Int. J. Pharm. 6:1980;285-294.
30. Denoyel R., Rouquerol J. Thermodynamic (including microcalorimetry) study of the adsorption of nonionic and ionic surfactants onto silica, kaolin and alumina. J. Colloid Interface Sci. 143:1991;555-572.
31. Dalgleish D.G. The sizes and conformations of the proteins in adsorbed layers of individual caseins on latices and in oil-in-water emulsions. Colloid Surf. B. 1:1993;1-8.
32. Lucks J.S., Müller B.W., Müller R.H. Inorganic suspensions-interaction with salts and ionic surfactants. Int. J. Pharm. 58:1990;229-235.
33. Law S.L. The effect of nonionic water soluble cellulose polymers on the settling of drug particles. Drug Dev. Ind. Pharm. 11:1985;2137-2142.
34. Sperry P.R., Hopfenbreg H.B., Thomas N.L. Flocculation of latex by water-soluble polymers: Experimental confirmation of a nonbridging, nonadsorptive, volume restriction mechanism. J. Colloid Interface Sci. 82:1981;62-76.
35. Milling A., Biggs S. Direct measurement of the depletion force using an atomic force microscopic. J. Colloid Interface Sci. 170:1995;604-606.
36. Liang W., Tadros Th.F., Luckham P. F Effect of volume fraction and particle size on depletion flocculation of a sterically stabilized latex dispersion induced by addition of poly(ethylene oxide). J. Colloid Interface Sci. 155:1993;156-164.
37. Zatz J.L. Physical stability of suspensions. J. Cosmet. Chem. 36:1985;393-411.